Page 103 - JSOM Spring 2018
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canines.  The same investigators reported their findings us-  and hypotension; have naloxone on hand to counter adverse
                    30
              ing this technique in clinical cases of GDV as compared with   effects of the opioid μ-agonist, if needed. In addition, avoid
              the standard GNDC techniques described in the previous sec-  administering over-the-counter nonsteroidal antiinflamma-
              tion.  In clinically affected dogs suffering GDV, the G-catheter   tory drugs developed for humans (e.g., ibuprofen, naproxen,
                 31
              technique did not differ significantly from standard GNDC in   meloxicam, aspirin) or corticosteroids (e.g., dexamethasone,
              regard to safety, time to place, success rate, complications, and   methylprednisolone, prednisone, hydrocortisone).
              decompression rate. The technique may be a viable tool for the
              tactical or SOF medic during situations when surgical delays   A Brief Look Into Surgery
              are unavoidable (e.g., prolonged field care).      Gastric repositioning with gastropexy, to prevent volvulus
                                                                 recurrence, is the surgical treatment of choice. Surgical man-
              Fluid Resuscitation                                agement of GDV involves an open exploratory laparotomy
              Fluid resuscitation to restore circulatory support and improve   via a large, ventral, midline incision while under general an-
              tissue perfusion and oxygenation is best accomplished via IV   esthesia. Minimally invasive techniques discussed previously
              or IO administration. For IV access, placing two large-bore   for performing a prophylactic gastropexy are not applicable
              catheters (14–18-gauge). IMPORTANT: Because of the ab-  for correction of GDV. These techniques make it difficult to
              dominal tourniquet effect of gastric distention, when estab-  appropriately perform gastric repositioning and to visualize
              lishing IV or IO access in a patient with GDV, always choose a   organs and structures within the abdominal cavity to assess
              location in the cranial half of the body (IV: cephalic vein in the   their viability.
              forelimb or external jugular vein; IO: proximal humerus). The
              ideal fluid choice is one or a combination of the following :  When combined with repositioning, gastropexy reduces the
                                                           5,6
                                                                 recurrence rate of GDV from 80% to 5% or lower.  Recur-
                                                                                                          24
                •  Isotonic electrolyte crystalloid solution (e.g., Plasmalyte-  rence rates after surgical correction may range from 0% to
                  A  [Baxter, http://ecatalog.baxter.com], lactated Ringer’s   20% and largely depend on the open gastropexy technique
                    ®
                  solution)                                      used; recurrence rates are lowest with incisional gastropexy
                •  Hypertonic saline solution                    techniques. 24–27  Gastropexy does not prevent simple GD,
                •  Synthetic hydroxyethyl starch solution (e.g. Hextend    only volvulus. The recurrence risk of GD without volvulus is
                                                             ®
                  [Biotime,  http://www.biotimeinc.com], Hespan  [B.   reported to range from 3.3% to 7.0%.  Depending on the
                                                                                                24
                                                         ®
                  Braun Medical, http://www.bbraunusa.com], Voluven    viability of the stomach wall (gastric necrosis) and spleen,
                                                             ®
                  [Fresenius-Kabi Norge, https://www.fresenius-kabi.com],   surgical intervention may also require partial removal of the
                  or VetStarch  [Zoetis Services, https://www.zoetisus.com).  stomach (partial gastrectomy) as well as removal of the spleen.
                            ®
                                                                 A splenectomy is performed if there is splenic torsion causing
              Suggested fluid resuscitation protocol (doses provided are for   strangulation of splenic vasculature and splenic infarction.
              25kg OpK9s):
                                                                 Postsurgical recovery
                •  Isotonic crystalloid: 20mL/kg (500mL)         The recovery time will depend on the severity and extent of
                •  3%–7.5% Hypertonic saline: 5mL/kg (125mL)     surgery as well as development of any postoperative compli-
                   o o Limit hypertonic saline administrations to no more than   cations. Barring any major complications and based on the
                     2 aliquots to prevent clinically relevant hypernatremia  OpK9s assigned mission (e.g., detection versus apprehension),
                •  Colloid only (low-molecular-weight 130/0.4 preferred)  recommended recovery times range from 14 to 21 days. An
                   o o 5–10mL/kg (125–250 mL)                    adequate recovery time is important to help ensure all surgical
                                                                 incisions have formed a tight, stable closure and the suture
              Resuscitative goals in the prehospital or field environment   line at the gastropexy site has formed permanent adhesion
              include acquisition of palpable femoral pulse and improved   to the abdominal wall. Postsurgical complications associated
              mentation, and MAP higher than 65mmHg; systolic blood   with GDV may include cardiac dysrhythmias, delayed stom-
              pressure, 80–90mmHg (if ability to measure blood pressure   ach and intestinal motility and function, vomiting, dehiscence
              is available); reassess perfusion parameters after each fluid   of surgical incisions, gastrointestinal ulceration, postopera-
              bolus; and reassess the casualty frequently to check for recur-  tive infections (sepsis), peritonitis, pancreatitis, disseminated
              rence of shock.                                    intravascular  coagulation, and/or  electrolyte  and acid–base
                                                                 disturbances. 4,6,32,33
              Miscellaneous Prehospital Treatments
              If  available,  provide  oxygen  supplementation  and  analge-  Prognosis
              sia. GDV is an extremely painful condition; therefore, a full
              μ-opioid agonist such as fentanyl and/or morphine is the pre-  GDV mortality rates depend on many perioperative factors.
              ferred analgesic drug. Consider the following dosages (for   Although mortality rates higher than 45% are reported even
              25kg OpK9s):                                       with prompt surgical intervention,  postsurgical mortality
                                                                                             4
                                                                 rates more commonly have been shown to be as low as 10%
                •  Fentanyl: 5μg/kg (125μg) IV/IO or intramuscular (IM)   and survival rates often approach 80%.  Prompt and ap-
                                                                                                 2,9
                  every 30–45 minutes                            propriate treatment is the most important factor influencing
                •  Morphine: 0.2–0.5mg/kg (5–10mg) IV/IO/IM every 1–4   survival. 9,32,33  One study revealed that timely preoperative sta-
                  hours, administered very slowly IV/IO.         bilization (i.e., gastric decompression, hemodynamic resuscita-
                                                                 tion) significantly lowered the mortality rate to 10% overall.
                                                                                                                9
              When administering opioids to a sick or injured OpK9, con-  Postoperatively, negative prognostic indicators include post-
              sider the following: Always start at low end of the dosage   operative cardiac arrhythmia, splenectomy, or splenectomy
              range and titrate to effect; monitor for respiratory depression   with partial gastric  resection. 32,33  The overall  prognosis for

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