Page 124 - JSOM Winter 2017
P. 124

segment of the eye will be affected, leading to irreversible
                                                               vision loss. The aqueous drain system can become blocked
                                                               owing to anatomic variations, changes in lens size, inflam-
                                                               mation, and trauma (Figure 20).



                                       Figure 18  Advanced
                                       corneal ulcer. (©2017
                                       American Academy of
                                       Ophthalmology, reprinted
                                       with permission.)     Figure 20  Angle-closure
                                                             glaucoma. (©2017
                                                             American Academy of
                  o Initiate pain control as needed. DO NOT use topical   Ophthalmology, reprinted
                 anesthetics for pain control; they significantly impair   with permission.)
                 corneal healing.                            ➤   Goals: Prompt diagnosis and identification, lowering of IOP.
                  Initiate teleconsultation with photographs.  ■   Minimum
                  o Activate evacuation (goal is ophthalmic care within     o Diagnosis
                 24 hours if lesion is large, central, or affects vision).  •  Pain (often described as a deep pain, similar to
            ■   Better                                                 tooth pain)
                  o Obtain  a  culture  before  beginning  treatment  for   •  Decrease in or loss of visual acuity
                 sight-threatening  or severe  keratitis with suspected   •  Photophobia
                 infection, such as large central corneal infiltrate that   •  Dull or cloudy appearance of the cornea due to
                 extends to the middle to deep stroma. 20              corneal edema
                  o Provide intense loading dose of moxifloxacin 0.5%   •  Fixed, mid-dilated pupil (usually occurs after IOP
                 eye drops 1 drop every 5–15 minutes for the first     reaches 30–40mmHg)
                 30–60 minutes (patient can self-administer loading   •  Increased IOP by palpation
                 dose if reliable) after culture obtained.           o Acetazolamide 500mg PO initial dose, then 250mg
                  o Treatment dose: 1 drop every 30–60 minutes around   PO every 4 hours to decrease IOP.
                 the clock until epithelial defect is closed. 20  (Note: contrain dicated in patients with sickle cell trait.)
                  o Cycloplegic eye drop (cyclopentolate 1%), 1 drop     Initiate teleconsultation with photographs.
                   every 8 hours for photophobia.                    o Activate evacuation with goal of evaluation by an
            ■   Best                                                eye surgeon within 24 hours.
                  Real-time video telemedicine consultation    ■   Better
                  o Collagen  corneal  shield  (national  stock  no.  [NSN]     o Oral acetazolamide  plus topical  IOP-lowering eye
                 6515-01-482-9391) soaked in moxifloxacin drops     drops (timolol 0.5%, 1 drop twice a day in the af-
                 for transport (generally 5–10 drops) and placed over   fected eye).
                 the corneal infiltrate. This enables release of the med-    o Administer antiemetics as required by patient symp-
                 ication to the ocular surface during transport, rather   toms (ondansetron 4mg ODT/IV/IO/IM every 8 hours
                 than administering repeated dosing. 21             as needed).
                  o No altitude restrictions for flight        ■   Best
            NOTE: Topical steroid drops may be useful to reduce in-    o Topical corticosteroids (prednisolone acetate 1%) 1
            flammation after the infection is controlled with topical   drop every hour after consultation with ophthalmol-
            antibiotics. Initiation of topical steroid drops should only   ogy or optometry.
            be done under the direction of an eye care specialist after     o 3% hypertonic saline 250mL IV or mannitol 1g/kg
            teleconsultation.                                       over 30–60 minutes can be used to decease IOP if the
            Herpes simplex virus (HSV) keratitis is an additional form   aforementioned interventions are not effective. 9
            of keratitis that usually occurs in patients with a history of   10.  Eye care in the multitrauma/thermal burn patient. Pa-
            previous episodes. HSV keratitis may demonstrate a spe-  tients with multisystem trauma who are intubated and se-
            cific dendritic staining pattern with fluorescein (Figure 19).   dated are at risk of developing corneal complications due
            After recognition, treatment can be initiated with oral acy-  to metabolic derangements and impaired ocular protec-
                                                                              22
            clovir (400mg PO 5 times per day).                   tive mechanisms.  The presence of thermal facial burns
          9.  Angle-closure glaucoma. Blockage of the normal flow of   puts  the  patient  at  high  risk  for  exposure  keratopathy.
            aqueous fluid in the anterior chamber of the eye will lead to   Loss of the normal blink reflex, impaired tear produc-
            increased IOP. If left untreated, blood flow to the posterior   tion, abnormal tear film dynamics, and incomplete eye-
                                                                 lid closure, combined with the inability to relay ocular
                                                                 complaints all contribute to the development of exposure
                                                                 keratopathy and increase the risk for infectious keratitis. 23
                                                                 If there is no concern for OGI, ultrasound examination
          Figure 19  Dendrite
          staining with fluorescein                              may be performed if personnel are equipped and trained.
          in herpes simplex keratitis.                           Patients with head and facial burns with eyelid involve-
          (http://EyeRounds.org/                                 ment are especially prone to entropion (with burned
          atlas/pages/HSV-keratitis;                             eyelash stubs abrading the cornea) as well as exposure
          reprinted with permission                              keratopathy from scar-related lid retraction and proptosis
          of The University of Iowa
          and EyeRounds.org.)                                    from orbital congestion (Figures 21 and 22).

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