Page 42 - JSOM Winter 2025
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Low-Tech Solutions for
                  Military Prehospital Medication Storage in Arctic Circumstances

                                                 A Feasibility Study



                                   Casper Matthias Fransen ; Benjamin Leslie Turner ;
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                    Thijs Theodorus Cornelis Franciscus van Dongen, MD, PhD ; René Joosten, MD ;
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                                           Beau ; Rigo Hoencamp, MD, PhD    6
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          ABSTRACT
          Introduction: Preventing temperature stress on medication   Introduction
          for prehospital medical care is a challenge, especially in re-
          source-limited environments like the Arctic. Most medication   Preventing temperature stress on medications for prehospital
          used by military prehospital providers is intended for storage   medical care is a major challenge. Within civilian prehospital
          between 15 and 25°C—defined as “controlled temperature.”   emergency medical services, maintaining temperature control
          The primary objective of this study was to demonstrate the   seems challenging to achieve, even under mild climatic con-
                                                                   1,2
          feasibility of storing medication within controlled parameters   ditions.  Multiday storage of medication and medical con-
          by a lightweight, highly mobile, and self-supporting Role 1   sumables during prehospital medical support to arctic military
          Medical Treatment Facility during cold weather operations.   operations is even more challenging. Currently, there is very
          Methods: Within a standard cooling container, we placed three   little literature on evidence based best practices for storing
          1L water bottles filled with boiling water, which were reheated   medication under such conditions. Low-tech, easy-to-deploy
          every morning. Over a period of 264 hours, we measured the   solutions should be researched in order to help austere mil-
          inside and outside temperatures of the container and analyzed   itary prehospital providers be and stay effective on the artic
          whether the inside temperature remained within the speci-  battlefield. The primary objective of this study was to demon-
          fied parameters using two TempTale  4 temperature loggers.   strate that it is feasible to store medications within controlled
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            Results: We collected a total of 264 hours of data. The ambi-  parameters by a lightweight, highly mobile and self- supporting
          ent temperature was outside the controlled temperature range   Role  1 Medical Treatment  Facility while  delivering  medical
          94.5% of the time (248.5 hours). We recorded a minimum   support in northern Norway.
          temperature of –12.5°C (9.5°F) and a maximum temperature
          of 27.3°C (81.1°F). The temperature measured inside the cool-  The Dutch Department of Defense pharmaceutical service (De-
          ing container was within the controlled temperature range for   fensie Farmaceutische Dienst – DFD) oversees and is responsi- 3
          67.8% of the time (178.3 hours), with a minimum tempera-  ble for the packaging, storage, and distribution of medications,
          ture of 6.2°C (43.2°F) and a maximum temperature of 36.7°C   which should be done in accordance with the guideline “Dis-
          (98.1°F). Conclusion: The shift in focus to arctic military op-  tribution practices” (“Goede distributiepraktijken” [GDP)] and
          erations must be accompanied by efforts to optimize military   Dutch Pharmacy requirements (Standaard Nederlandse Apoth-
          arctic medical preparedness. During arctic warfare one of the   eek Norm [NAN]).
          biggest challenges is the low and uncontrollable temperature
          which can create significant stress on medical equipment. The   Most medications commonly used by military prehospital pro-
          demonstrated low-tech, easy-to-deploy solution is a first step   viders are intended for storage at a “controlled temperature,”
          to keep medication within controlled parameters in a mini-  which is between 15 and 25°C (59–77°F), according to DFD’s
          mally equipped Role 1 Medical  Treatment Facility without   definition. The arctic military out-of-hospital environment is
          reliance on running vehicles or electric/fuel-powered heating.   notoriously “uncontrolled” with temperature being one of the
          This method not only lowered the team’s logistical load but   biggest challenging factors.
          also reduced their thermal signature. This study paves the way
          for more research toward robust medical readiness in arctic   Cold environments with temperatures below the freezing
          military operations.                               point (0°C/32°F) present challenges for certain medications,
                                                             especially those in aqueous solutions. In the past, this was
          Keywords: arctic warfare; temperature stress; prehospital   mitigated by keeping medication within constantly running
          medical care; resource-limited environments; cold weather   vehicles or by using electric or fuel-powered heating. How-
          operations; medication storage; low tech; deep ops; Role 1  ever, these options consume a significant amount of electricity
          1 Casper Matthias Fransen is affiliated with the Ministry of Defense, The Netherlands.  Benjamin Leslie Turner is affiliated with the Ministry
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          of Defense, The Netherlands.  Dr. Thijs Theodorus Cornelis Franciscus van Dongen is affiliated with the Ministry of Defense, The Netherlands
          and the Defense Healthcare Organisation, Ministry of Defense, Utrecht, The Netherlands.  Dr. René Joosten is affiliated with the Ministry of
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          Defense, The Netherlands and the Defense Healthcare Organisation, Ministry of Defense, Utrecht, The Netherlands.  LCpl Beau is affiliated with
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          the Ministry of Defense, The Netherlands.  Dr. Rigo Hoencamp is affiliated with the Ministry of Defense, The Netherlands, the Department of
          Surgery, Alrijne Hospital, Leiderdorp, The Netherlands, the Defense Healthcare Organisation, Ministry of Defense, Utrecht, The Netherlands, and
          the Trauma Research Unit, Department of Surgery, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, the Netherlands.
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