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the team’s movement with the BV 206. While driving the BV   Prehospital military medical teams should consider the im-
          206, the internal heating system turns on and blows hot engine   plications of our findings when developing solutions for the
          air inside the vehicle. Because of this the difference between   storage of medication under arctic prehospital circumstances.
          the inner and outer temperatures of the cooling container di-  However, further research is needed to explore the impact of
          minished and the warm water bottles started overheating the   different protocols and technologies and their effectiveness in
          container. Another possible explanation is that the TempTale 4   various operational settings.
          might have been too close to the warm water bottles.
                                                             Recommendation
          Our data indicate that medication storage in this manner is still   Further research should focus on temperature-controlled med-
          not compliant with current regulations concerning the storage   ication storage during arctic deployments. In our opinion this
          of medications by the DFD. However, the temperature had been   can be done by using smaller and better cooling containers
          within the parameters for controlled temperature for almost   and applying a stricter protocol. This protocol should at least
          70% of the time. This indicates that a low-tech, easy-to-maintain     specify when water bottles need to be reheated and where the
          method of prehospital medication storage is within reach of   temperature sensors should be positioned within the cooling
          mandated requirements. Minor adjustments in our proof-of-  container in a way that they are not accidentally heated by
          concept protocol could lead to total thermal range coverage.  the warm bottles. If operational circumstances allow, water
                                                             should be warmed twice a day and, if not possible, prefera-
          A review of literature has shown the difficulties of keeping   bly before night falls. It would also be beneficial to research
          medication within a controlled temperature in civilian emer-  this method when operating on small open mobility platforms
          gency medical services (EMS).  Nevertheless, existing litera-  such as snowmobiles.
                                  4–6
          ture does not document any low-tech solutions for medication
          storage in cold arctic conditions. Our study presents a novel   Conclusion
          way of using a cooling container to keep medication at storage
          temperature without using electricity. Notably, our findings in-  The shift in focus to arctic military operations must be ac-
          dicate that the cooling container maintained a stable internal   companied by efforts to optimize military arctic medical pre-
          temperature for about 70% of the observed time, in a manner   paredness. During arctic warfare, one of the biggest challenges
          not previously reported.                           is the low and uncontrollable temperature which can create
                                                             significant stress on medical equipment.  This demonstrated,
          The main strength of our study resides in the operational con-  low-tech, easy-to-deploy solution is a first step to keeping med-
          text in which the research was conducted. A small medical   ication within controlled parameters in a minimally equipped
          team collected these data while executing a full mission profile   Role 1 Medical Treatment Facility, without reliance on running
          during a large-scale military cold weather exercise. The exten-  vehicles or electric/fuel-powered heating. This method not only
          sive duration of data collection, encompassing 264 hours of   lowered the team’s logistical load but also reduced their ther-
          continuous monitoring and yielding approximately 5,300 data   mal signature. This research paves the way for more research
          points, has resulted in a robust dataset for analysis. Another   towards robust medical readiness in arctic military operations.
          strength of this study lays in the possible application of similar
          storage methods for other purposes, such as batteries used for   Author Contributions
          communication and optical equipment. This could potentially   CMF designed this research, collected, and analyzed the data
          help them stay at full capacity during freezing temperatures.  and drafted the original manuscript. BLT analyzed the data
                                                             and edited the manuscript.  TCFD reviewed and edited the
          Limitations                                        manuscript.  RJ  collected  the  data,  reviewed,  and  edited  the
          There are potential limitations to our methodology. There was   manuscript. LCpl Beau reviewed and edited the manuscript.
          a pragmatic selection of the cooling container, solely based   RH reviewed and edited the manuscript. All authors read and
          on direct availability for the medical team in theater. Cool-  approved the final manuscript.
          ing/warming containers with better isolation specifications
          might exist. No strict protocol dictating the rewarming of the   Disclaimer
          three Nalgene bottles was provided; instead, the team did so   The opinions or assertions contained herein are the private
          according to their battle rhythm every morning while making   views of the authors and are not to be construed as official or
          breakfast. Furthermore, the placement of the cooling container   reflecting the views of the Dutch Department of Defense or
          within one of the BV 206s significantly mitigated its exposure   Dutch government. Five of the authors are employees of the
          to arctic temperatures compared to a less sheltered position,   Dutch government.
          such as when operating on snowmobiles or being man-packed.
          While a BV 206 is optimal, further research should also explore   Disclosures
          the feasibility of this method when operating in a more tem-  The authors have nothing to disclose.
          perature-exposed manner. Additionally, while the TempTale 4
          is a reliable instrument, factors such as sensor calibration and   Funding
          placement (e.g., being too close to the hot water sources) could   This research was supported by the Netherlands Ministry of
          introduce random errors or systemic biases, potentially affect-  Defense.
          ing the accuracy of the recorded temperature data.
                                                             References
          Despite these weaknesses, the strengths of our field-ready ap-  1.  Helm M, Castner T, Lampl L. Environmental temperature stress
          proach include the comprehensive data collection and detailed   on drugs in prehospital emergency medical service. Acta Anaesthe-
          analysis, suggesting that the potential errors are unlikely to   siol Scand. 2003;47(4):425–429. doi:10.1034/j.1399-6576.2003.
          account for any significant discrepancies in our findings.  00062.x

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