Page 127 - 2023 SMOG Digital

DEXTROSE 50% Lactation? Trade Name: Glutose / B-D Glucose
Class / Mechanism of Action
Antidote, Hypoglycemia
Basic source of calories (fuel) for the body and brain, regulated by insulin. Rapidly increases blood
glucose, decreases protein and nitrogen loss, preventing ketosis, and promotes glycogen deposition in
liver.
Onset of action: Treatment of hypoglycemia Oral dose: 10minutes
Maximum effect: Treatment of Hyperkalemia IV: 30minutes
Indications
Labeled Indications: Treatment of:
• Hypoglycemia: Doses may be repeated in severe cases
• Hyperkalemia: (Must be used in combination WITH Insulin)
Contraindications
• Known Hyperglycemia, otherwise None in the Pre-hospital setting
Adverse Reactions / Precautions
Most adverse effects associated with excessive dose or infusion rate
• If evidence of malnutrition or alcohol abuse, thiamine should be given 1 st
• Tissue Necrosis if Extravasation occurs; immediately D/C and change IV site
• Hyperglycemia
• Hypokalemia
• Hyponatremia
Dose and Administration: ADULT PEDIATRIC Always Reference BROSELOW Tape
Hypoglycemia: Hypoglycemia:
Oral: Oral:
• 4-20g as a single dose; may repeat if • 4-20g as a single dose; may repeat if
necessary necessary
IV: IV:
• 10-25g (40-100mL of 25% solution or • Newborns: 5ml/kg D10 (Max 25g/dose)
20-50mL of 50% solution) • Infants and Children: 2ml/kg D25 (Max
25g/dose)
Note: Society of Critical Care Medicine
recommends: Treat blood glucose <70mg/dL • Adolescents: Refer to adult dosing
(<100mg/dL in patients with neurologic injury)
immediately by stopping insulin therapy (if Note:
receiving) and administering 10-20g (20-40mL of • D25=25ml NS + 25ml D50 (12.5g in 50ml's
50% solution) IV; repeat blood glucose solution)
measurement in 15 minutes with repeat dextrose • D10=100ml NS + 25ml D50 (12.5g in 125ml's
as needed; avoiding overcorrection. solution)
or
40ml NS + 10ml D50 (5g in 50ml's solution)

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