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A Systematic Review of
                                    Prehospital Combat Airway Management



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                                          Shane Smith, MD, MSc *; Michael Liu, MD ;
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                            Ian Ball, MD, MSc ; Bethann Meunier, MD ; Richard Hilsden, MD, MBA   5
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              ABSTRACT
              Medical leadership must decide how prehospital airways will   Methods
              be managed in a combat environment, and airway skills can be   We conducted a search in Medline and EMBASE databases.
              complicated and difficult to learn. Evidence informed airway   The search terms included combinations of the following
              strategies are essential. A search was conducted in Medline   subject headings and keywords: airway, prehospital, crico-
              and EMBASE databases for prehospital combat airway use.   thyroidotomy, endotracheal intubation, nasopharyngeal, oro-
              The  primary  data  of  interest  was  what  type  of  airway  was   pharyngeal, supraglottic, combat, military medicine, warfare,
              used. Other data reviewed included: who performed the in-  armed conflict, and battlefield. Searches were restricted to hu-
              tervention and the success rate of the intervention. The search   mans and adults. No language restrictions were applied. Stud-
              strategy produced 2,624 results, of which 18 were included   ies of airway techniques performed in the prehospital combat
              in the final analysis. Endotracheal intubation, cricothyroidot-  environment were included. Studies were excluded if the pa-
              omy, supraglottic airways, and nasopharyngeal airways have   tients were less than 18 years old, if it was an animal study,
              all been used in the prehospital combat environment.  This   or if it was a case report or review article. Our focus was on
              review summarizes the entirety of the available combat lit-  the types of airways that were used, the provider type, and
              erature such that commanders may make an evidence-based   the success rates. Note that for provider type, the language in
              informed decision with respect to their airway management     each original reference was replicated, with the understanding
              policies.                                          the definitions and training requirements for such positions as
                                                                 paramedic, medic, and combat medic may not be comparable
              Keywords: endotracheal intubation; airway; cricothyroidot-  between  studies.  No publication time  restrictions  were im-
              omy; supraglottic airways; and nasopharyngeal airways  posed. All studies were uploaded into Cochrane’s Covidence.
                                                                 org reference management system. This review was registered
                                                                 on the PROSPERO Registry (2018CRD42018102976).  All
              Introduction                                       studies were subject to a title and abstract review by two in-
                                                                 dependent examiners (RH, ML). A third party was used to re-
              Military medical leaders must decide how prehospital com-  solve any conflicts (SS). Remaining studies were subject to full
              bat airways will be managed and what training is required for   text screening, in which studies failing the inclusion/exclusion
              prehospital providers. As with most wartime medical research,   criteria were discarded using the same three-reviewer system.
              this area is difficult to study with the same level of method-
              ological rigour that  is achievable in a civilian environment.   Results
              Despite  the available  research  being  heterogeneous  and of   The search strategy produced 2,624 results, of which 728 du-
              variable quality, it is important to summarize lessons learned   plicates were removed. This resulted in 1,896 papers which
              during conflicts.                                  were subject to title and abstract review. Of these, 1,825 were
                                                                 excluded for not meeting inclusion criteria. Seventy-one studies
              Airway skills are difficult to learn and maintain.  Moreover,   underwent full text review. Fifty-two were removed for the fol-
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              managing an airway while wearing personal protective equip-  lowing reasons: 33 had the incorrect study design, 11 had the
              ment in an austere environment poses different challenges than   incorrect patient population, three were duplicate studies, four
              the civilian prehospital experience. Inadequate training may   were the incorrect intervention, and two where the full text was
              lead to significant patient morbidity and mortality, as well as   unavailable. Eighteen studies were included in the final review,
              mental health sequelae to providers. Military decision- makers   which ranged in publication date from 2008 to 2018.
              need an evidence base upon which to provide policy with re-
              spect to training, resources, and in-theatre decision-making.
              The purpose of this document is to summarize the available   Endotracheal Intubation
              prehospital combat airway literature in order to better inform   Thirteen studies reported on endotracheal intubation. Seven
              mission planning and decision-making.              from the war in Afghanistan, three from the war in Iraq, two

              *Correspondence to shane.smith@lhsc.on.ca
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              1 Shane Smith and  Richard Hilsden are affiliated with the Royal Canadian Medical Service, Ottawa, ON, Canada and the Department of Surgery,
              University of Western Ontario, London, ON, Canada.  Bethann Meunier is affiliated with the Royal Canadian Medical Service, Ottawa, ON,
                                                    4
              Canada and with the Department of Anesthesia and Perioperative Medicine, Queen’s University, Kingston, ON, Canada.  Michael Liu is affiliated
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              with the Royal Canadian Medical Service, Ottawa, ON, Canada.  Ian Ball is affiliated with the Royal Canadian Medical Service, Ottawa, ON,
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              Canada, and the Departments of Medicine, Epidemiology and Biostatistics at the University of Western Ontario, London, ON, Canada.
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