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filters that do not have heat-and-moisture-exchange properties   6.  GE Healthcare Life Care Solutions Datex-Ohmeda. Topic:
          are available and may be a useful alternative. These types of   COVID-19 – Requests for information regarding the off-label
          viral filters are commonly used on the exhaust port of ICU   use of GE Healthcare anesthesia devices for ICU ventilation. 23
          ventilators and may be available, although they do add nota-  March 2020. https://www.gehealthcare.com/-/jssmedia/3c655c83
                                                                bd6b427e9824994c12be0da5.pdf?la=en-us.
          ble dead space and may not have a sampling port for gas anal-  7.  Asrat S. Mechanical Ventilation Wave Forms. Slide presentation.
          ysis. Note that Draeger, Medtronic, Pall, and others produce   https://www.slideshare.net/sintubeyene/mechanical-ventilation
                                                     5
          quality viral filters with sampling ports for gas analysis.  If the   -wave-forms.
          anesthesia machine has a heated breathing system, some an-  8.  Drägerwerk AG. COVID-19: Usage of Dräger anesthesia devices
          esthesia machine manufacturers recommend that the heating   for long-term ventilation. Letter to customers and healthcare
          remain active for long-term therapy. 6–11             professionals. 19 May 2020.  https://www.draeger.com/Library
                                                                /Content/Draeger-Customer-Letter-Covid19-Usage-Anaesthesia
                                                                -devices-for-long-term-ventilation.pdf.
          Inhalation Therapy Management                       9.  Mindray North America. Mindray A-Series Anesthesia Delivery
                                                                System Consideration for use as a Ventilator. Letter to custom-
          Nebulization of drugs and aerosol therapy are not approved   ers. 23 March 2020. https://www.mindraynorthamerica.com/wp
          with most anesthesia machines. 6–11  If aerosol or other drugs   -content/uploads/2020/03/1658B-Considerations-for-MR
          are given to the airways, malfunctions can occur. Without a   -Anes-Sys-used-for-Ventilators-during-COVID-19-1.pdf.
          mechanical filter between the connection port of the nebulizer   10.  Getinge. COVID-19 Pandemic: Ventilating ICU patients using
                                                                Flow-I, Flow-c and Flow-e anesthesia machines. Customer no-
          and the anesthesia machine, malfunctions are likely to occur   tification letter. 10 April 2020.  https://www.getinge.com/dam
          (e.g., incorrect measurement of the gas analyzer; erroneous   /hospital/documents/english/mcv00103387_reva_covid-19_
          measurement of expiratory flows, tidal and minute volumes).   customer_letter_long_term_ventilation_with_flow-en-us.pdf.
          If no mechanical filter is used on the Y-piece, disconnect the   11.  Mindray North America. Mindray A-Series Anesthesia Delivery
          sampling gas line during nebulization and aerosol therapy.  System: Consideration for use as a Ventilator. Addendum – Proce-
                                                                dures for Converting Drive Gas from Oxygen to Air. 30 March 2020.
                                                                https://www.mindraynorthamerica.com/wp-content/uploads
          Conclusion                                            /2020/03/1659B-Considerations-for-MR-Anes-Sys-used-for
                                                                -Vent-during-COVID-19-Air-Drive-Gas-Addendum.pdf.
          This article is not intended to provide clinical guidance; we   12.  Azami T, Preiss D, Somogyi R, et al. Calculations of O  consump-
                                                                                                     2
          recognize that others have produced recommendations on the   tion during low-flow anesthesia from tidal gas concentrations,
          clinical management of SARS-Cov-2 virus. 13-15  Further, the in-  flowmeter, and minute ventilation. J Clin Monit Comput. 2004;
          tent is not to duplicate high-quality existing advice regarding   18(5–6):325–332.
          mass critical care or crisis surge response. 16–19  We recommend   13.  Aziz S, Arabi YM, Alhazzani W, et al. Managing ICU surge during
                                                                the COVID-19 crisis: rapid guidelines. Intensive Care Med. 2020;
          that important considerations be reviewed prior to using an   46(7):1303–1325.
          anesthesia machine for long-term ventilation in a critical care   14.  World Health Organization. Clinical management of severe acute
          setting. There are significant differences with modes of venti-  respiratory infection  (SARI) when COVID-19  disease is sus-
          lation, fresh gas and flow capabilities, inhalation and carbon   pected: interim guidance. 13 March 2020. https://www.who.int
          dioxide management, alarm notifications and settings, as well   /docs/default-source/coronaviruse/clinical-management-of-novel
          as suction and filter requirements.                   -cov.pdf?sfvrsn=bc7da517_2. Accessed 4 May 2021.
                                                             15.  Alhazzani W, Møller MH, Arabi YM, et al. Surviving Sepsis
                                                                Campaign: guidelines on the management of critically ill adults
          Disclosure                                            with coronavirus disease 2019 (COVID-19). Intensive Care Med.
          The authors have nothing to disclose.                 2020;46(5):854–887.
                                                             16.  Christian MD, Devereaux AV, Dichter JR, et al; Task Force for
                                                                Mass Critical Care. Introduction and executive summary: care
          References
          1.  US Food and Drug Administration. Ventilator Supply Mitiga-  of the critically ill and injured during pandemics and disasters:
            tion Strategies: Letter to Health Care Providers. 22 March 2020.   CHEST consensus statement. Chest. 2014;146(4 Suppl):8S–34S.
            https://www.fda.gov/medical-devices/letters-health-care-providers   17.  Devereaux A, Christian MD, Dichter JR, et al; Task Force for
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            machines-for-ventilators. Updated 7 May 2020.       -health-care-crisis-standards-of-care-and-novel-coronavirus-sars
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            2020;14(7):e01234.                                  ciety of Intensive Care Medicine Task Force for Intensive Care
          4.  American  Society  of Anesthesiologists. 2008  ASA Recommen-  Unit Triage during an Influenza Epidemic or Mass Disaster. Rec-
            dations for Pre Anesthesia Checkout.  https://www.asahq.org   ommendations for intensive care unit and hospital preparations
            /standards-and-guidelines/2008-asa-recommendations-for-pre   for an influenza epidemic or mass disaster: summary report of
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            Use,  Protection,  and  Decontamination  During  the  COVID-19   disaster. Intensive Care Med. 2010;36(3):428–443.
            Pandemic. Updated 19 February 2021.  https://www.apsf.org/faq
            -on-anesthesia-machine-use-protection-and-decontamination
            -during-the-covid-19-pandemic/.







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