Page 139 - 2023 SMOG Digital

ETOMIDATE Lactation? (Caution) Trade Name: Amidate
Class / Mechanism of Action
General Anesthetic
Very short acting non-barbiturate sedative/hypnotic used for induction of anesthesia with little
cardiovascular effects. Onset of action: 30-60 seconds, Duration 5-10 minutes
Indications
Labeled Indications:
• Rapid Sequence Induction
Contraindications
• Hypersensitivity to etomidate or any component of the formulation
Adverse Reactions / Precautions
• NO Analgesic properties!
• Safety in children less than 10 years has not been established
• Inhibits adrenal steroid production; may increase mortality if repeat dosing is required
Dose and Administration: ADULT PEDIATRIC Always Reference BROSELOW Tape
RSI: RSI:
IV: IV:
• 0.3mg/kg over 30-60 seconds for induction of Children <10
anesthesia; • Despite dosing on Broselow tape, not the
preferred induction agent for this group due to
Note: Limit to single dose for anesthesia/induction. limited safety information
Repeat dosing and continuous infusion Children >10:
(maintenance dosing) may increase patient • 0.3mg/kg over 30-60 seconds will produce
mortality due to adrenal suppression and inability to rapid sedation lasting 10-15 minutes.
respond to stress.
o Max dose: 20mg
Note: Limit to single dose for anesthesia/induction.
Repeat dosing and continuous infusion
(maintenance dosing) may increase patient
mortality due to adrenal suppression and inability to
respond to stress.

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