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Ertapenem Lactation Yes Trade Name: Invanz
Class / Mechanism of Action
Antibiotic (Carbapenem),
Biacteriocidal – broad spectrum, Inhibits bacterial cell wall synthesis by binding to one or more of
penicillin-binding proteins which inhibits cell wall biosynthesis, causing bacteria to eventually lyse.
Labeled Indications: Used for infection control prophylaxis for traumatic open injuries and surgical
prophylaxis.
Contraindications
• Hypersensitivity to cefazolin, other cephalosporin antibiotics, other beta-lactams, or any component of
the formulation
Adverse Reactions / Precautions
• Superinfection – prolonged use may result in fungal or bacterial superinfection (including C.Difficile)
Dose and Administration: ADULT PEDIATRIC
Infection Control: Infection Control: Children <12 years & ≥12 years
Give 1g in 250mL NS IV over 5min, provides 24
hours of coverage.
IV:
IV: Pediatrics:
Adults: • <12years old: 15mg/kg IV q12hr
• 1g IV q24hr o Max daily dose: 100mg/kg/day
o Max daily dose: 12g/day
• ≥12 years old: 20mg/kg IV or IM once daily
o Max daily dose: 1g/day

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