Page 121 - JSOM Winter 2024
P. 121
38. Staresinic M, Japjec M, Vranes H, et al. Stable gastric pentadeca- Rev Psiquiatr Salud Ment (Engl Ed). 2019;12(3):170–186. doi:
peptide BPC 157 and striated, smooth, and heart muscle. Biomed- 10.1016/j.rpsm.2018.09.002
icines. 2022;10(12):3221. doi:10.3390/biomedicines10123221 58. Chinthapalli K. The billion dollar business of being smart. BMJ.
39. Gwyer D, Wragg NM, Wilson SL. Gastric pentadecapeptide body 2015;351:h4829. doi:10.1136/bmj.h4829
protection compound BPC 157 and its role in accelerating mus- 59. Food and Drug Administration. Tianeptine in dietary supple-
culoskeletal soft tissue healing. Cell Tissue Res. 2019;377(2):153– ments. Accessed November 28, 2023. https://www.fda.gov/food/
159. doi:10.1007/s00441-019-03016-8 dietary-supplement-ingredient-directory/tianeptine-dietary-
40. Kviatkovsky SA, Hickner RC, Ormsbee MJ. Collagen peptide supplements
supplementation for pain and function: is it effective? Curr Opin 60. Food and Drug Administration. FDA warns consumers not to
Clin Nutr Metab Care. 2022;25(6):401–406. doi:10.1097/mco. purchase or use Neptune’s Fix or any tianeptine product due to
0000000000000870 serious risks. Accessed January 22, 2024. https://www.fda.gov/
41. Rustad AM, Nickles MA, McKenney JE, Bilimoria SN, Lio PA. drugs/drug-safety-and-availability/fda-warns-consumers-not-
Myths and media in oral collagen supplementation for the skin, purchase-or-use-neptunes-fix-or-any-tianeptine-product-due-
nails, and hair: a review. J Cosmet Dermatol. 2022;21(2):438– serious-risks
443. doi:10.1111/jocd.14567 61. Department of Justice. Tianeptine. Accessed January 22, 2024.
42. Khatri M, Naughton RJ, Clifford T, Harper LD, Corr L. The ef- https://www.deadiversion.usdoj.gov/drug_chem_info/tianeptine.
fects of collagen peptide supplementation on body composition, pdf
collagen synthesis, and recovery from joint injury and exercise: 62. Food and Drug Administration. FDA takes action on products
a systematic review. Amino Acids. 2021;53(10):1493–1506. doi: marketed as dietary supplements containing tianeptine and
10.1007/s00726-021-03072-x warns consumers. Accessed January 22, 2024. https://www.fda.
43. Kim DU, Chung HC, Choi J, Sakai Y, Lee BY. Oral intake of gov/food/cfsan-constituent-updates/fda-takes-action-products-
low-molecular-weight collagen peptide improves hydration, elas- marketed-dietary-supplements-containing-tianeptine-and-warns
ticity, and wrinkling in human skin: a randomized, double-blind, -consumers
placebo-controlled study. Nutrients. 2018;10(7):826. doi:10.3390/ 63. Food and Drug Administration. Tianeptine products linked to
nu10070826 serious harm, overdoses, death. Accessed November 28, 2023.
44. Mobasheri A, Mahmoudian A, Kalvaityte U, et al. A white paper https://www.fda.gov/consumers/consumer-updates/tianeptine-
on collagen hydrolyzates and ultrahydrolyzates: potential supple- products-linked-serious-harm-overdoses-death
ments to support joint health in osteoarthritis? Curr Rheumatol 64. Food and Drug Administration. 5 things to know about delta-8 tet-
Rep. 2021;23(11):78. doi:10.1007/s11926-021-01042-6 rahydrocannabinol: delta-8 THC. Mo Med. 2022;119(1):21–22.
45. Martínez-Puig D, Costa-Larrión E, Rubio-Rodríguez N, Gálvez- 65. LoParco CR, Rossheim ME, Walters ST, Zhou Z, Olsson S,
Martín P. Collagen supplementation for joint health: the link be- Sussman SY. Delta-8 tetrahydrocannabinol: a scoping review and
tween composition and scientific knowledge. Nutrients. 2023;15 commentary. Addiction. 2023;118(6):1011–1028. doi:10.1111/
(6):1332. doi:10.3390/nu15061332 add.16142
46. Kim J, Lee SG, Lee J, et al. Oral supplementation of low-molecu- 66. Livingston MD, Walker A, Cannell MB, Rossheim ME. Popularity
lar-weight collagen peptides reduces skin wrinkles and improves of delta-8 THC on the internet across US states, 2021. Am J Public
biophysical properties of skin: a randomized, double-blinded, Health. 2022;112(2):296–299. doi:10.2105/ajph.2021.306586
placebo-controlled study. J Med Food. 2022;25(12):1146–1154. 67. Centers for Disease Control and Prevention. CDC health advi-
doi:10.1089/jmf.2022.K.0097 sory: increases in availability of cannabis products containing
47. Walrand S, Chiotelli E, Noirt F, Mwewa S, Lassel T. Consump- delta-8 THC and reported cases of adverse events. Accessed No-
tion of a functional fermented milk containing collagen hydroly- vember 28, 2023. https://emergency.cdc.gov/han/2021/pdf/CDC_
sate improves the concentration of collagen-specific amino acids HAN__451.pdf
in plasma. J Agric Food Chem. 2008;56(17):7790–7795. doi: 68. Nali MC, McMann TJ, Purushothaman V, et al. Assessing char-
10.1021/jf800691f acteristics and compliance of online delta-8 tetrahydrocannabinol
48. Xie Z, Wang X, Yu S, et al. Antioxidant and functional properties product sellers. Cannabis Cannabinoid Res. 2024;9(4):e1132–
of cowhide collagen peptides. J Food Sci. 2021;86(5):1802–1818. e1141. doi:10.1089/can.2022.0341
doi:10.1111/1750-3841.15666 69. Babalonis S, Raup-Konsavage WM, Akpunonu PD, Balla A,
49. Jeong S, Yoon S, Kim S, et al. Anti-wrinkle benefits of peptides Vrana KE. Δ(8)-THC: legal status, widespread availability, and
complex stimulating skin basement membrane proteins expres- safety concerns. Cannabis Cannabinoid Res. 2021;6(5):362–365.
sion. Int J Mol Sci. 2019;21(1):73. doi:10.3390/ijms21010073 doi:10.1089/can.2021.0097
50. Barati M, Jabbari M, Navekar R, et al. Collagen supplementation 70. Ray CL, Bylo MP, Pescaglia J, Gawenis JA, Greenlief CM. Delta-8
for skin health: a mechanistic systematic review. J Cosmet Derma- tetrahydrocannabinol product impurities. Molecules. 2022;27
tol. 2020;19(11):2820–2829. doi:10.1111/jocd.13435 (20):6924. doi:10.3390/molecules27206924
51. Michienzi AE, Borek HA. Emerging agents of substance use/ 71. Meehan-Atrash J, Rahman I. Novel Δ (8)-tetrahydrocannabinol
misuse. Emerg Med Clin North Am. 2022;40(2):265–281. doi: vaporizers contain unlabeled adulterants, unintended byprod-
10.1016/j.emc.2022.01.001 ucts of chemical synthesis, and heavy metals. Chem Res Toxicol.
52. Edinoff AN, Sall S, Beckman SP, et al. Tianeptine, an antidepres- 2022;35(1):73–76. doi:10.1021/acs.chemrestox.1c00388
sant with opioid agonist effects: pharmacology and abuse poten- 72. Eichner AK, Coyles J, Fedoruk M, et al. Essential features of
tial, a narrative review. Pain Ther. 2023;12(5):1121–1134. doi: third-party certification programs for dietary supplements: a con-
10.1007/s40122-023-00539-5 sensus statement. Curr Sports Med Rep. 2019;18(5):178–182.
53. Karim A, Ioannou C. Tianeptine abuse leading to an episode of doi:10.1249/jsr.0000000000000595
psychosis: a case report and literature review. J Psychiatr Pract. 73. Consortium for Health and Military Performance. Check your
2020;26(2):146–148. doi:10.1097/pra.0000000000000448 supplement. Operation Supplement Safety (OPSS). Accessed No-
54. Wilde MI, Benfield P. Tianeptine. A review of its pharmacody- vember 26, 2024. https://www.opss.org/opss-scorecard-check-
namic and pharmacokinetic properties, and therapeutic efficacy your-dietary-supplement
in depression and coexisting anxiety and depression. Drugs. 74. Consortium for Health and Military Performance. Ask the ex-
1995;49(3):411–439. doi:10.2165/00003495-199549030-00007 pert. Operation Supplement Safety (OPSS). Accessed November
55. Wagner ML, Pergolizzi J Jr, LeQuang JAK, Breve F, Varrassi G. 26, 2024. https://www.opss.org/ask-the-expert
From antidepressant tianeptine to street drug zaza: a narrative 75. Consortium for Health and Military Performance. DoD Pro-
review. Cureus. 2023;15(6):e40688. doi:10.7759/cureus.40688 hibited Dietary Supplement Ingredients. Operation Supplement
56. Uzbay TI. Tianeptine: potential influences on neuroplasticity Safety (OPSS). Accessed November 26, 2024. https://www.opss.
and novel pharmacological effects. Prog Neuropsychopharma- org/dod-prohibited-dietary-supplement-ingredients
col Biol Psychiatry. 2008;32(4):915–924. doi:10.1016/j.pnpbp. 76. Consortium for Health and Military Performance. Performance
2007.08.007 enhancing substances. Operation Supplement Safety (OPSS). Ac-
57. Alamo C, García-Garcia P, Lopez-Muñoz F, Zaragozá C. Tianep- cessed November 26, 2024. https://www.opss.org/performance
tine, an atypical pharmacological approach to depression. -enhancing-substances
Tianeptina, un abordaje farmacológico atípico de la depresión. PMID: 39641609; DOI: 10.55460/A580-YJ5A
Dietary Supplements in the Military | 119

