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          location ). The forearm Ratcheting Medical Tourniquet loca-  Dory et al. 2014  for the  TPT2 on the SynDaver ®13  and
                                                                           15
          tion in that study was one fourth of the distance from the el-  HapMed Trainers  correspond with our observations of the
                                  5
          bow crease to the wrist crease,  so not as distal as was TPT2   pressure-induced, transiently red areas on legs immediately
          placement in this study.                           following TPT2 removal (Table 1). Namely, the TPT2 does
                                                             not exert the same pressure across its entire width. 13,15  As
          Regarding the arterial occlusion pressure differences between   the TPT2 is inflated, it rounds and does not exert pressure
          the TPT2 and 3.8cm-wide emergency-use limb tourniquets, the   across  a  full  5.1cm, and  of  the  width  that is  exerting  pres-
          limitations of using a small, inflated bladder under only one   sure, the highest pressure is exerted at the middle, with much
          portion of the 3.8cm-wide tourniquet to provide pressure data   less pressure exerted toward the edges. 13,15  Because the TPT2
          are unlikely to account for the observed pressure differences.   bladder rounds with inflation, differences  in limb or device
          The thigh and forearm comparison pressures were for Ratch-  surface indentation in response to tourniquet pressure appli-
          eting Medical Tourniquet pressures that were one ladder tooth   cation will affect the width over which the TPT2 is exerting
          advance past arterial occlusion and were only for applications   pressure.
          that maintained arterial occlusion for 60 seconds or longer du-
          ration as specified in each study.  Therefore, the pressures at   The  TPT2 was  not  designed  to be  an  emergency-use  limb
                                   4–9
          which arterial occlusion occurred with the 3.8cm-wide Ratch-  tourniquet but rather as a pneumatic tourniquet that might
          eting Medical Tourniquets were even lower than the pressures   be considered for use in an out-of-hospital situation such as a
          presented for comparison with those of the TPT2 in this study.  field aid station replacement of an initial emergency-use limb
                                                             tourniquet with an alternate tourniquet. Considering the 13
          Regarding non-pneumatic emergency-use limb tourniquets of   thighs without occlusion and the high pressures required for
          the same width as the deflated TPT2, thigh arterial occlusion   the successful thigh occlusions, this study indicates the TPT2 is
          was achieved in each of 360 applications with the 5.1cm-wide   a suboptimal choice of tourniquet for such use.
          OMNA Marine emergency-use limb tourniquet (OMNA,
          www.omnainc.com).  Across the 60 subjects in the OMNA   It is possible that filling the bladder of the TPT2 via the hand
                          11
          Marine tourniquet study, the 5th to 95th percentile pressures   bulb rather than via the stopcock system with the pressure
          at which thigh arterial occlusion was achieved were 289–  sensor and the 60mL syringe, might have allowed reaching
          541mmHg with a median of 348mmHg.  The thighs ranged   arterial occlusion on the larger thighs without the difficulties
                                          11
          in circumference from 42.0–76.0cm, and systolic blood pres-  encountered regarding pushing air from the 60mL syringe into
          sures ranged from 84–136mmHg. 11                   the TPT2 at TPT2 pressures over 700mmHg. However, the
                                                             pressures required to reach arterial occlusion on those thighs
          Searches of PubMed and Google Scholar only revealed three   would still have been unacceptably high. 24
          published original research reports involving the  TPT2. 19–21
          Three additional original research reports involving the   Study Limitations
          TPT2 exist as Naval Medical Research Unit San Antonio re-  In addition to the standard laboratory limitations such as no
                                        19
          ports. 13,15,22   Only in the  Beaven  et  al.   study was  the TPT2   actual bleeding, good lighting, limited distractions, and calm
          applied to human subjects. The number of subjects was 12,   subjects, the subjects were a convenience sample recruited
          and all had mid-thigh arterial occlusion with the TPT2, but   from friends; college students, faculty, and staff; and surgical
          no limb circumference, blood pressure, or tourniquet pressure   residents,  medical  students,  and trauma  center  staff.  Addi-
          information was provided. 19                       tionally, 100% side-to-side overlap of each inner and outer
                                                             strap wrap was closely checked in these applications, and that
          In the 2016 report by Dory et al.,  the TPT2 was applied to the   would not be likely in non-laboratory applications.
                                   13
                                        ®
          clothed proximal thigh of a SynDaver  (SynDaver, syndaver.
          com) with a pump circulating water through the vasculature.   Conclusions
          The circumference of the SynDaver thigh was not provided.
          The internal tourniquet pressure was not provided. The aver-  The TPT2 is likely to be useful for developing emergency-use
          age contact pressures for occlusion of the SynDaver thigh with   limb tourniquet certification device pressures, but it is not a
          three non-pneumatic emergency-use limb tourniquets were all   desirable tourniquet for any in- or out-of-hospital clinical use.
          lower than the occlusive pressures reported for those tourni-
          quets on the thighs of live human subjects. 4,6–10  The three other   Acknowledgments
          tourniquets were the Combat Application Tourniquet (C-A-T   The authors thank the following Drake University under-
          Resources, LLC,  http://combattourniquet.com/), 6,10  Tactical   graduates of the Trauma Research Team for their help car-
          Ratcheting  Medical Tourniquet, 4,6–9  and Special Operations   rying out the experiments: Jack Libbesmeier, Justin Akolith,
          Forces Tactical Tourniquet-Wide (Tactical Medical  Solutions,   Abby Minten, Gage Vander Leest, Nia Eberhard-Mattes, Mary
                                                 ®
          www.tacmedsolutions.com). 10                         Jonas, Jordyn Carter, Gillian Galinsky, Nick Mishu, McKenna
                                                             Nelson, Abishag  NiCuai, Tiffani White,  Rylee  Beardsworth,
          The other four reports 15,20–22  involved  TPT2 application to   Adrianna Clark, Ella Kocina, Adaire MacSwain, and Fiona
          HapMed  Tourniquet  Trainers (CHI Systems, Inc., www.   Martin.
          hapmedtraining.com), which are not suitable for determining
          likely tourniquet effectiveness nor occlusive pressures (see Wall   Author Contributions
          et al.  for a discussion of HapMed unsuitability regarding ar-  PW and CB contributed to concept development. PW, CB, DE,
              23
          terial occlusion effectiveness and arterial occlusion pressure).  TR, and CR contributed to project design. All authors con-
                                                             tributed to the acquisition, analysis, and interpretation of data
                         ®
          The Tekscan I-Scan  (Tekscan, Inc., www.tekscan.com) pres-  and the drafting or revising of the article. All authors had final
                                                     13
          sure distribution profiles shown in Dory et al. 2016  and   approval of the manuscript.
          16  |  JSOM   Volume 23, Edition 1 / Spring 2024
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