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It is clear that there are many systemic differences at play in the
                                                                 war in Ukraine compared with the GWOT, both in the tactical
                                                                 environment as well as the model of training and protocoliza-
                                                                 tion. It is not known whether there were medical indications
                                                                 in these cases. However, we can hypothetically apply GWOT,
                                                                 Israeli, and other data, and extrapolate from these reports that
                                                                 rates of prolonged application are high. 32,33  It would seem very
                                              FIGURE 1           probable that the number-needed-to-treat per tourniquet ap-
                                              A resuscitation area   plication for mortality benefit in the war in Ukraine war is less
                                              in Ukraine, where   favorable than that of the GWOT.
                                              tourniquets are
                                              routinely washed and
                                              re-used for multiple   More data are necessary to understand the impact of the
                                              patients.          heavily condensed training, based on TCCC/TECC concepts,
                                                                 deployed in rapid fashion to Ukrainian Servicemembers and
                                                                 medical personnel. However, we have identified three major
                                                                 factors impacting tourniquet practices: prolonged evacuation
                                                                 times, rigid protocolization of concepts, and systemic differ-
                                                                 ences in the definition, training, and availability of field med-
                                                                 ics. Understanding how these factors interact with existing
                                                                 TCCC/TECC paradigms is crucial to guide interventions.

              Tourniquet indications can be tactical or medical; tactical   Evacuation Times
              indications are notoriously difficult to analyze in retrospect.   In the war in Ukraine, evacuation time is likely the most signifi-
              Lessons learned from the U.S. SOF community emphasize that   cant factor impacting tourniquet complications. In the absence
              promoting other means to control hemorrhage while under   of air superiority or mobile aid stations, evacuation times are
              immediate danger places both the casualty and responder at   reported to be significantly longer than those in the GWOT,
                         26
              increased risk.  Although TCCC guidelines contemplate tour-  when there was reliance on chains of evacuation composed
              niquet application under fire as an appropriate stopgap to   of multiple echelons of care and air transport, which typically
              manage “life-threatening hemorrhage,” this condition can be   delivered patients to definitive care within 1 hour. 2,14,30,31,34  In
              difficult to diagnose under duress of immediate threat. Studies   near-peer conflicts, evacuation resources are likely to be lim-
              have found that the majority of tourniquets placed at or near   ited by contested airspace, resulting in more prolonged, com-
              the POI are not medically indicated. 27,28         plex, high-risk  ground  evacuation platforms. Unpublished
                                                                 reports and sources on the ground report that current casualty
              A four-year review by Israeli Defense Forces (IDF), also a pro-  evacuation times to the first facility in Ukraine often exceed
              ponent of liberal tourniquet practices, concluded that 54% of   the 4-hour mark and frequently go beyond 12 hours.
              tourniquets had “situational and non-medical” indications.
                                                            27
              In a U.S. study of GWOT casualties, 74% of limbs with   The body of evidence documenting the safety of tourniquets
              tourniquets applied in the field did not have a major vascu-  reports exceedingly low rates of usage over 150 minutes, and
              lar injury, and 83% of tourniquets were venous, meaning the   cases that exceed this duration are outliers with high rates
              placement was tight enough to occlude venous but not arterial   of morbidity.  7,8,10,14,27,31   The mean time of tourniquet dura-
              flow.   While  these tourniquets  may  have initially  been ap-  tion in the IDF study was 78 minutes, and all but one of the
                 28
              plied correctly, tourniquets will loosen over time due to mus-  small number of complications observed were in cases with
                                                                                   27
              cle relaxation, fluid shift, and blood loss.  Without  proper   times over 150 minutes.  Since 2001, there has been only one
                                               29
              re-evaluation and tightening, tourniquets can become venous,   known case of inappropriate limb loss by a U.S. Servicemem-
              which increases the risk of ongoing arterial bleeding. Mis-  ber due to prolonged tourniquet use. During a 2014 combat
              uses such as these are common, even when applied by highly   mission in Africa, a tourniquet placed high and tight on a limb
              trained operators. 7,14,26,27                      was not found by medical personnel until 8 hours after ap-
                                                                 plication. There was ultimately no vascular injury, and med-
              By the end of the GWOT, the tourniquet pendulum had   ical personnel believed that the amputation would have been
              swung to the point where they were routinely applied to mi-  avoided with earlier tourniquet conversion. 14
              nor wounds during Care Under Fire (CUF), usually “high and
              tight.” 14,30  This trend has continued in the war in Ukraine, with   Shackelford et al. anticipated the issue of prolonged evacua-
              tourniquets being liberally applied at the POI for any signs of   tion impacting TCCC paradigms in future conflicts in their
                                                                                             14
              limb trauma. They are then often left on without clear reas-  2014 proposal of guideline changes.  A need for clarification
              sessment until arrival at the first receiving facility. The NGO   and increased training on tourniquet conversion was empha-
              medic from Case 2 observed that in 18 months working in   sized, noting that as a result of the short evacuation times in
              CCP settings, including personal assessments of approximately   GWOT, attempts to convert tourniquet to hemostatic dress-
              25 casualties, they did not see any cases in which conversion   ings had been “de-emphasized in practice by users,” despite
              had been attempted during prolonged evacuation wait times.   the recommendation in guidelines that tourniquets placed in
              Multiple other sources in similar positions reported the same   CUF should be re-evaluated in the Tactical Field Care (TFC)
                                                                           14
              observation—conversion is often first attempted at the receiv-  phase of care.  This trend in GWOT is understandable given
              ing surgical facility. The lack of tourniquet conversion occur-  that casualties arrived in a facility within minutes, and the
              ring in the field is complicated and multifactorial and will be   data analysis by the JTR revealed no complications from this
              addressed further in the discussion.               practice.

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