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Analgesia and Sedation in the Prehospital Setting

                                             A Critical Care Viewpoint



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                          Taylor T. DesRosiers, MD *; Justin L. Anderson, BHS, SO-ATP, NRP ;
                                        Brit Adams, NRP ; Ryan A. Carver, MD  4
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          ABSTRACT
          Pain is one of the most common complaints of battlefield casu-  only.  Sedation is a drug-induced decreased level of conscious-
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          alties, and unique considerations apply in the tactical environ-  ness, the depth or degree of which ranges from anxiolysis to
          ment when managing the pain of wounded service members.   deep sedation, per the American Society of Anesthesiologists.
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          The resource constraints commonly experienced in an opera-  Relevant to this guideline are moderate sedation, which is a
          tional setting, plus the likelihood of prolonged casualty care   one-time event typically done to assist a procedure; dissocia-
          by medics or corpsmen on future battlefields, necessitates a   tive sedation, which is achieved through the administration
          review of analgesia and sedation in the prehospital setting.   of ketamine; and deep sedation, which is typically performed
          Four clinical scenarios highlight the spectrum of analgesia and   over a prolonged period for critically ill or injured patients. In
          sedation that may be necessary in this prehospital and/or aus-  most cases, sedation does not typically provide analgesia, and
          tere environment.                                  additional pain medication is required.
          Keywords:  pain;  analgesia; sedation;  ketamine;  opioids;  fen-  The  JSOM Critical Care Supplement  is intended to address
          tanyl; guideline; military; operational; deployed; battlefield;   appropriate pain control and sedation in the prehospital/pro-
          prehospital                                        longed casualty care setting across a variety of skill levels and
                                                             severities of injury. This guide is meant to promote treatment
                                                             appropriate to the degree of injury, emphasizing expedient re-
                                                             turn to duty. However, for those too severely wounded to con-
          Introduction
                                                             tribute to the fighting force, aggressive pain control and even
          Pain is one of the most common complaints of battlefield ca-  total sedation might be appropriate. Because the possibility
          sualties, and analgesia (i.e., pain management) has been an   of near-peer conflict arises in situations where air superiority
          integral part of war for thousands of years. From the Romans’   may not be the reality, prolonged care for casualties may be-
          use of cool water, mandrake, and other natural remedies to   come standard in prehospital or Role 1 care. Therefore, this
          the United States’ cutting-edge pharmacologic therapy, multi-  supplement will also address the critical aspects of longer-term
          ple modalities and treatments have accompanied prehospital   pain  control, sedation,  and  necessary  monitoring  across  all
          care.  Adequate pain control decreases deleterious outcomes,   spectrums of injury.
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          such as chronic pain and posttraumatic stress disorder.  An-
                                                     2,3
          algesia should be given when feasible after injury or as soon as
          possible after the management of MARCH (i.e., massive hem-  Cases
          orrhage, airway, respiration, circulation, hypothermia preven-  Four Joint Services casualties are brought to a Role 1 facility.
          tion). This must be appropriately documented, including all   They were injured after an improvised explosive device deto-
          details of the specific medication, dose, route, and time. Also,   nated as they were exiting their vehicle during a joint exercise.
          there may be tactical factors for delaying pain management   The medical team, of which you are part, has the typical Role
          (e.g., the need for the individual to maintain a weapon or se-  1 capabilities, primarily immediate life-saving supplies. As a
          curity). The goal is to provide appropriate pain management   Role 1 provider, you may expect to hold casualties up to 72
          while simultaneously protecting the patient’s hemodynamic   hours. This is particularly likely given that your unit does not
          status, as well as operational safety and feasibility.  always have the ability to undertake expedient evacuations be-
                                                             cause of the near-peer environment in which you are now op-
          A second goal of the practitioner may then be acute or pro-  erating. Additionally, you may be responsible for transporting
          longed sedation. Sedation and analgesia are separate treat-  these casualties when evacuation does arrive, which could take
          ments  with different  therapeutic goals.  Analgesia is  the   more than 16 hours. Your team has had inconsistent commu-
          decreased sensation of pain, and treatment has been simplified   nication over the last few days, and you know there may be
          over time by use of the Tactical Combat Casualty Care (TCCC)   options for air drops (e.g., equipment, medication) that may
          guidelines to allow for the safe administration of medications   include medication outside traditional TCCC guidelines—for
          without the need for advanced monitoring for pain control   example, other parenteral (intramuscular [IM], intranasal
          *Correspondence to taylor.t.desrosiers@gmail.com
          1 Taylor T. DesRosiers is affiliated with Walter Reed National Military Medical Center, Bethesda, MD; Uniformed Services University of the
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          Health Sciences, Bethesda; and the Combat Trauma Research Group, United States Department of the Navy.  Justin L. Anderson is affiliated with
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          US Army Special Operations Command, Fort Bragg, NC.  Brit Adams is affiliated with the Joint Trauma Service, San Antonio, TX.  Dr Carver
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          is affiliated with Eastern Virginia Medical School, Norfolk, VA.
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