Page 32 - 2022 Spring JSOM
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TABLE 10  Continued
                                  PCC Role-based Guideline for Pain Management (Analgesia and Sedation)
           TCCC - Drug/Interactions/Dose           Onset      Duration                Side Effects
            CPP  Ketamine                         30 sec IV or    10–15 min IV or  •  Cataleptic-like state (dissociated from the surrounding
                 •  Moderate to severe pain, unable to fight with   1–5 min IM  20–30 min IM  environment)
                   hemorrhagic shock or respiratory distress            •  Respiratory depression at higher doses (>1mg/kg),
                 •  30mg (or 0.3mg/kg) slow IV or IO push every          especially with fast administration IV/IO
                   20 min                                               •  Hypersalivation (can be problematic in an austere setting)
                 •  May repeat                                          •  Increased blood pressure and heart rate.
                 •  Ketamine 50–100mg (or 0.5–1 mg/kg) IM or            •  Nausea/vomiting
                   IN every 20–30 min
                 •  May repeat
                 For sedation
                 •  1–2mg/kg slow IV push initial dose
                 •  300mg IM (or 2–3mg/kg IM) initial dose
                 For longer duration analgesia
                 •  Slow IV infusion 0.3mg/kg in 100mL 0.9%
                   sodium chloride over 5–15 min every 45 min
                   prn for IV or IO
                 •  When available and applicable, other medications can be considered.
                 •  These medications should be used based on local protocols and policies put in place by your medical director or through direct teleconsultation
                   guidance.
                 Midazolam (Versed)               15–20 mins   1–6 hrs when   •  Drowsiness
                 •  For sedation and anxiolysis; will also cause   when given IM,    given IM,    •  Respiratory depression ESPECIALLY when used with any
                   anterograde amnesia           2 mins when   15 min–   narcotic
                 •  2–4mg IM                       given IV  6 hrs (HIGH   •  Nausea/vomiting
                 •  0.5–1mg IV (push slowly over 1–2 min)     variability)
                 Acetaminophen/Hydrocodone (Norco)  10–20 minutes  3–4 hours  •  Drowsiness
                 •  For moderate-severe pain                            •  Respiratory depression
                 •  Comes in multiple strengths of hydrocodone –        •  Sedation
                   5/7.5.10mg                                           •  Nausea/vomiting
                 •  1–2 tabs PO every 4–6 hours PRN for 5mg             •  Itching
                   hydrocodone strength                                 Note: contains acetaminophen. Be aware of total dose when
                                                                        given with other drugs that contain acetaminophen.
                 Acetaminophen/Oxycodone (Percocet)                     •  Drowsiness
                 •  For moderate-severe pain                            •  Respiratory depression
                 •  Comes in multiple strengths of oxycodone –          •  Sedation
                   5/7.5/10mg                                           •  Nausea/vomiting
                 •  1–2 tabs PO every 4–6 hours PRN for 5mg             •  Itching
                   oxycodone dose                                       Note: contains acetaminophen. Be aware of total dose when
                                                                        given with other drugs that contain acetaminophen.
                 Hydromorphone (Dilaudid)                               •  Drowsiness
                 •  For severe pain                                     •  Respiratory depression
                 •  1–2 mg IM                                           •  Sedation
                 •  0.5–1mg IV                                          •  Nausea/vomiting
                                                                        •  Itching
                 Morphine                                               •  Drowsiness
                 •  For severe pain                                     •  Respiratory depression
                 •  5–0mg IM                                            •  Sedation
                 •  2–4mg IV                                            •  Nausea/vomiting
                                                                        •  Itching
                 Tramadol (Ultram)                                      •  Drowsiness
                 •  For moderate-severe pain                            •  Respiratory depression
                 •  1–2 tabs PO every 4–6 hours PRN                     •  Sedation
                   (DO NOT exceed 400mg tramadol/day)                   •  Nausea/vomiting
                                                                        •  CNS stimulation including seizures at high doses
                                                                        Note: Some preparations (i.e., Ultram) contain
                                                                        acetaminophen. Be aware of total dose when given with
                                                                        other drugs that contain acetaminophen.
                 Codeine/acetaminophen           30 minutes –    4–6 hours  •  Drowsiness
                 •  For moderate-severe pain       1 hour               •  Respiratory depression
                 •  1–2 tabs PO every 4–6 hours PRN                     •  Sedation
                   (for tabs with 15mg Codeine)                         •  Nausea/vomiting
                                                                        •  Itching
                                                                        Note: Contains acetaminophen. Be aware of total dose when
                                                                        given with other drugs that contain acetaminophen.
                 •  In some cases, local anesthetics or even limited regional anesthesia is the best option for pain control (For more information, see Military Analgesia
                   Regional Anesthesia Guidelines.)
                 •  While side effects are real and toxic levels of these drugs must be understood and avoided, the benefit can often be achieved without sedation when
                   appropriate for the tactical environment.


          medics should be trained to this standard), and the best option that   Use these steps when referencing the tables:
          may only be available in the event a medic has had additional training,   Step 1.  Identify the clinical condition
          experience, and/or available equipment.            ■   Standard analgesia is for most patients. The therapies used here
                                                               are the foundation for pain management during PCC. Expertise
          Medications in the table are presented as either give or consider:  in dosing fentanyl (OTFC or IV) and ketamine IV or IO is a must.
          ■   Give: Strongly recommended.                      Intramuscular and intranasal dosing of medications isn’t recom-
          ■   Consider: Requires a complete assessment of patient condition, en-  mended in a PCC setting.
            vironment, risks, benefits, equipment, and provider training.


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