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TABLE 10  PCC Role-based Guideline for Pain Management (Analgesia and Sedation)
                                      PCC Role-based Guideline for Pain Management (Analgesia and Sedation)
              TCCC - TCCC - TCCC - TCCC -  Complete Basic TCCC Communication Plan for Pain Management then:
               ASM    CLS  CMC    CPP  •  Administer meloxicam and acetaminophen (pain medications in Joint First Aid Kit [JFAK]) per TCCC guidelines if
                                         not already given.
                                       •  Identify painful conditions that can be treated without the use of medications.
                                            o Fractures – apply splint per TCCC guidelines.
                                            o Exposed burns – burn care per TCCC guidelines.
                                            o Tourniquets will cause significant pain – DO NOT remove a tourniquet in an attempt to alleviate pain unless
                                           directed to do so by a higher medical authority.
                                       Drug/Interactions/Dose           Onset    Duration        Side Effects
                                       Acetaminophen                   <1 hr when   4–6 hr  •  Allergic Reaction (rare)
                                       •  Mild-moderate pain, able to fight  given by    •  Liver damage: limit daily dose
                                       •  Use with meloxicam             mouth             of acetaminophen and
                                       •  1g every 6 hr                                    acetaminophen-containing
                                                                                           products (e.g., Percocet) to
                                                                                           4,000mg/day
                                       Meloxicam                       <1 hr when   24 hr  •  Reflux
                                       •  Mild-moderate pain, able to fight  given by    •  Abdominal pain
                                       •  Use with acetaminophen         mouth           •  Nausea/vomiting
                                       •  15mg daily                                     •  Diarrhea and/or constipation
                                       Administer meloxicam and acetaminophen (in JFAK) per TCCC guidelines if not already given.
                                       •  Pain medications should be given when feasible after injury or as soon as possible after the management of MARCH
                                         and appropriately documented (medication administered, dose, route and time).
                                       •  Pain meds initiated in TCCC can often be continued in the PCC environment for both ongoing analgesia and sedation,
                                         as long as the duration and cumulative side effects are well understood and mitigated.
                                       OTFC (Oral Transmucosal Fentanyl Citrate)  5 min when   20–40 min  •  Respiratory/cardiac/mental
                                       •  Moderate to severe pain, unable to fight   given by mouth  status depression
                                         without hemorrhagic shock or respiratory          •  Nausea/vomiting
                                         distress                                          •  Pruritus (itching)
                                       •  800mcg every 30 min                              •  Constipation
                                       Ketamine                         30 sec IV or    10–15 min  •  Cataleptic-like state
                                       •  Moderate to severe pain, unable to fight with   1–5 min IM  IV or 20–30   (dissociated from the
                                         hemorrhagic shock or respiratory distress  min IM   surrounding environment)
                                       •  30mg (or 0.3mg/kg) slow IV or IO push every      •  Respiratory depression at
                                         20 min                                              higher doses (>1mg/kg),
                                       •  May repeat                                         especially with fast
                                       •  Ketamine 50–100mg (or 0.5–1mg/kg) IM or            administration IV/IO
                                         IN every 20–30 min                                •  Hypersalivation (can be
                                       •  May repeat                                         problematic in an austere
                                       For Sedation                                          setting)
                                       •  1–2mg/kg slow IV push initial dose               •  Increased blood pressure and
                                       •  300mg IM (or 2–3mg/kg IM) initial dose             heart rate
                                       •  May repeat                                       •  Nausea/vomiting
                                       Ondansetron (Zofran)             30 min – hr   3–6 hr  •  Drowsiness
                                       •  For nausea/vomiting          when given PO       •  Fatigue
                                       •  1–2 tabs PO/SL every 4–6 hr PRN  or SL, 5–10 min   •  Anxiety
                                       •  4mg IV, may repeat 1 time in 2 hr if    when given IV
                                         N/V returns
                                       Naloxone (Narcan)               1–2 min IV or   30–90 min  •  Abrupt withdrawal reaction
                                       •  For complete or partial reversal of opioid   2–5 min IM/IO  Note: some   from opioid depression
                                         depression (respiratory/cardiac/mental)    opioids   should be anticipated and
                                       •  0.4–2mg IV/IM/IO                        have longer   preparations should be made.
                                       •  May repeat every 2–3 min (MAX dose 10mg)  duration so  •  This reaction may include
                                                                                   naloxone   vomiting, sweating,
                                                                                  may need to   tachycardia, increased blood
                                                                                  be repeated  pressure, agitation.
                                       •  Pain medications should be given when feasible after injury or as soon as possible after the management of MARCH
                                         and appropriately documented (medication administered, dose, route and time).
                                       •  Pain meds that are initiated in TCCC can often be continued in the PCC environment for both ongoing analgesia and
                                         sedation, as long as the duration and cumulative side effects are well understood and mitigated.
                                       Fentanyl                        1–2 min when   30–60 min  •  Respiratory/cardiac/mental
                                       •  Moderate to severe pain, unable to fight   given IV  status depression
                                         without hemorrhagic shock or respiratory          •  Nausea/vomiting
                                         distress                                          •  Pruritus (itching)
                                       •  50mcg IV (0.5–1mcg/kg) or 100mcg IN, may         •  Constipation
                                         repeat every 1–2 hr
                                                                                                          (continues)
              If a continuous drip is selected, use only a ketamine drip in most situa-  consider dilution of 0.4mg of naloxone in 9mL saline (40mcg/mL)
              tions, augmented by push doses of opioid and/or midazolam if needed.   and administer 40mcg IV/IO PRN to increase respiratory rate, but still
              Multiple drips are difficult to manage and should only be undertaken   maintaining pain control.
              with assistance from a Teleconsultation with critical care experience.   The PCC Pain Management Guideline Tables
              Multiple drips are most likely to be helpful in patients who remain   These tables are intended to be a quick reference guide but are not
              difficult to sedate with ketamine drip alone and can “smooth out” the   standalone: you must know the information in the rest of the guide-
              sedation (e.g., fewer peaks and troughs of sedation with correspond-  line. The tables are arranged according to anticipated clinical con-
              ing deep sedation mixed with periods of acute agitation).
                                                                 ditions, corresponding goals of care, and the capabilities needed to
              Other medications that should be available when providing narcotic   provide effective analgesia and sedation according to the minimum
              pain control is Naloxone. If the patient receives too much medication,   standard, a better option when mission and equipment support (all

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