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had pressure losses within 5mmHg of their loss plateaus   3.  Wall PL, Sahr SM, Buising CM. Different width and tightening
          and close to 1mmHg of their loss plateaus within 10   system emergency tourniquets on distal limb segments. J Spec
          minutes on the thigh.                                Oper Med. 2015;15:28–38.
                                                             4.  King DR, van der Wilden G, Kragh JF Jr, Blackbourne LH.
                                                               Forward assessment of 79 prehospital battlefield tourniquets
          This study has the limitation of one tourniquet recipi-  used in the current war. J Spec Op Med. 2012;12:33–38.
          ent. The advantages of one recipient are control of the   5.  Kragh JF Jr, O’Neill ML, Walters TJ, et al. Minor morbidity
          tourniquet-important variables blood pressure, circum-  with emergency tourniquet use to stop bleeding in severe limb
          ference, and tissue composition. Additionally, using one   trauma: research, history, and reconciling advocates and aboli-
                                                               tionists. Mil Med. 2011;176:817–823.
          recipient allowed gel-circumference matching to the   6.  Shackelford SA, Butler FK, Kragh JF Jr, et al. Optimizing the
          thigh, thigh-image matching across applications, and   use of limb tourniquets in tactical combat casualty care: TCCC
          subjecting only one author to 300 second tourniquet   guidelines change 14-02. J Spec Oper Med. 2015;15:17–31.
          durations and tourniquet pressures higher than needed   7.  Biehl WC, Morgan JM, Wagner FW, Gabriel RA. The safety of
                                                               the Esmarch tourniquet. Foot Ankle. 1993;14:278–283.
          for arterial occlusion. The gel cylinders’ limitations are   8.  Schindelin J, Arganda-Carreras I, Frise E, et al. Fiji: an open-
          as follows: the gels do not compositionally match a hu-  source  platform for biological-image  analysis.  Nat Methods.
          man limb; the gel pressure decays are not identical to   2012;9:676–682.
          those of a thigh; and gels suffer some surface tearing   9.  Slaven SE, Wall PL, Rinker JH, et al. Initial tourniquet pressure
          that does not occur with skin. The cylinders’ benefits   does not affect tourniquet arterial occlusion pressure. J Spec
          were a precise and static experimental set-up, the abil-  Oper Med. 2015;15:39–49.
          ity to rule out free fluid movement, use of size-matched
          cylinders with different resistances to distortion in re-
          sponse to mechanical load (Poisson’s ratios), extension   Ms Rometti was an undergraduate research mentor in the
          of tourniquet  durations, and repair  with heat (270°F   Biochemistry, Cell and Molecular Biology Program at Drake
          [132°C] melting temperature).                      University, Des Moines, Iowa, and is now a medical student
                                                             at the University of Kansas School of Medicine, Kansas City,
          Conclusion                                         Kansas.

          Even without tourniquet movement or limb muscle    Dr Wall is a researcher in the Surgery Education Department
          tension changes, pressure losses occur within minutes   of UnityPoint Health Iowa Methodist Medical Center, Des
          under tourniquets. These pressure losses are substantial   Moines, Iowa. E-mail: piperwall@q.com.
          with nonelastic tourniquets. Therefore, proper initial
          tourniquet application does not guarantee maintenance   Dr Buising is a professor of biology and Director of the Bio-
          of arterial occlusion. Given the opportunity, tourniquet   chemistry, Cell and Molecular Biology Program at Drake Uni-
                                                             versity, Des Moines, Iowa.
          applications should be reassessed for continued arterial
          occlusion 5 or 10 minutes after application.       Ms Gildemaster was an undergraduate research mentor
                                                             in the Biochemistry, Cell and Molecular Biology Program at
          Disclosures                                        Drake University, Des Moines, Iowa, and is now a research
                                                             associate at Kemin Food Technology.
          None of the authors have any financial relationships rel-
          evant to this article to disclose, and there was no outside   Dr Hopkins is a retired pediatric surgeon and a researcher in
          funding.                                           the Surgery Education Department of UnityPoint Health Iowa
                                                             Methodist Medical Center, Des Moines, Iowa.
          References                                         Dr Sahr is a trauma surgeon at UnityPoint Health Iowa
          1.  Wall PL, Duevel DC, Hassan MB, et al. Tourniquets and oc-  Methodist Medical Center, Des Moines, Iowa.
            clusion: the pressure of design. Mil Med. 2013;178:578–587.
          2.  Wall PL, Coughlin O, Rometti M, et al. Tourniquet pressures:
            strap width and tensioning system widths. J Spec Oper Med.
            2014;14:19–29.
















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