Page 158 - 2023 SMOG Digital
P. 158

METHYLPREDNISOLONE        Lactation Yes(Caution)   Trade Name: SoluMedrol
          Class / Mechanism of Action
          Systemic Corticosteroid
          Anti-inflammatory, Immunosuppressant, shock
          Indications
          Labeled Indications: Treatment of a variety of diseases: allergic, inflammatory, hematologic, neoplastic,
          and autoimmune;
          Unlabeled:
          None identified unless added by medical direction.
          Contraindications
          •  Hypersensitivity to methylprednisolone or any component of the formulation
          •  No other in emergency setting
          Adverse Reactions / Precautions
          •  Not for use in treatment of head injury; increased mortality has occurred in head injury patients
            treated with high dose IV methylprednisolone.
          •  No immediate effect will be observed while treating in the pre-hospital environment. Onset of action
            may take several hours
          Dose and Administration: ADULT    PEDIATRIC Always Reference BROSELOW Tape
          Asthma exacerbations, including status   Asthma exacerbations, including status
          asthmaticus                   asthmaticus
          IV:                           IV:
          •  125mg x 1 dose             •  Children <12 years: 1-2mg/kg initial dose;
                                           followed by 0.5-1mg/kg q6hr (maximum:
          Allergic Reaction:               60mg/day)
          IV:
          •  125mg x 1 dose             Allergic Reaction
                                        IV
                                        •  2mg/kg x 1 dose
          Note: Only methylprednisolone sodium succinate
          can be used for IV doses.     Note: Only methylprednisolone sodium succinate
                                        can be used for IV doses.




















        158
   153   154   155   156   157   158   159   160   161   162   163