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HETASTARCH Lactation Yes (Caution) Trade Name: Hextend
Class / Mechanism of Action
Plasma Volume Expander, Colloid
Colloidal starch producing plasma volume expansion. Onset of Action: approximately 30 minutes
Indications
Labeled Indications: Volume expander used in treatment of hypovolemic / hemorrhagic shock
Contraindications
• Hypersensitivity to hydroxyethyl starch or any component of the formulation
• Renal failure with oliguria and anuria (not related to Hypovolemia)
• Fluid overload conditions, (pulmonary edema, congestive heart failure
• Pre-existing bleeding or coagulation disorders (eg, von Willebrand’s disease): Use caution in bleeding
disorders; may increase risk of more bleeding
Adverse Reactions / Precautions
• Anaphylactoid reactions (allergies to corn)
Dose and Administration: ADULT PEDIATRIC Always Reference BROSELOW Tape
Plasma volume expansion:
IV
• 250-500mL Bolus. May repeat prn (up to
1500 mL/day). Titrate to individual
hemodynamic needs (Sys BP >90).
Notes:
• May be administered via infusion pump or
pressure infusion.
• Do not administer with blood through the same
line/tubing
• Change tubing or flush extensively with NS
before administering blood through the same
line.
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