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Discussion                                         Limitations
                                                             Our study has several limitations. There are ethical issues with
          Surgical Teams Can Rapidly Learn How to            performing training and validation testing on humans, so we
          Cannulate and Manage VV ECMO                       used an animal model as a substitute. There are similarities in
          We developed a VV ECMO training course that combined   anatomy between human and swine anatomy; however, the
          didactic, skills station, and model training to teach SOSTs to   femoral anatomy is more tortuous in swine.  Given the ana-
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          cannulate and manage VV ECMO. Our course was unique   tomical differences in the femoral anatomy in swine, bifemo-
          in that SOST personnel may not have access to perfusionists   ral VV ECMO cannulation is likely more challenging than in
          or ECMO specialists and may be required to independently   humans. Second, validation testing occurred immediately after
          manage both the patient and the  VV ECMO equipment.   didactic training, so sustainment and retention of training was
          In addition, SOSTs operate in austere conditions and may   not studied. Follow-on studies will examine length of time of
          need to perform advanced procedures in low light condi-  skills retention and adjuncts that can be used to refresh knowl-
          tions. Though no participants had formal ECMO training   edge. Third, we did train participants to manage and perform
          prior to this course, surgical teams consist of personnel with   procedural interventions on  VV ECMO; however, only 2
          extensive  medical  expertise  and  experience.  Course  partic-  hours per scenario was allocated. PCC tuations may require
          ipants were able to understand the physiology and man-  longer holding of patients on VV ECMO prior to transfer to
          agement of VV ECMO in addition to the technical aspects   experienced ECMO management teams. Use of operational
          of the procedure. They were then able to independently set   VV ECMO SMEs and further prolonged management train-
          up and prime the VV ECMO circuit and cannulate models   ing through didactics and exercises will be important in im-
          for VV ECMO. Prior to the course, no participants met the   plementation of  VV ECMO in forward locations. Fourth,
          80%  standard  of  knowledge to perform VV ECMO. After   given operational and training requirements, obtaining two
          completing  training,  75% met this standard.  In addition,   6-person teams with each AFSC represented was not feasible
          participants were able to perform ECMO circuit set-up and   so substitutions to the usual team composition was necessary
          cannulation at or below previously established times. Finally,   for this study. This could limit broader applicability to SOST
          participants successfully managed all alarms and emergency   implementation of VV ECMO. Fifth, 6 participants had spe-
          scenarios. Our study demonstrates similar findings to a pre-  cialized training in advanced vascular access courses which
          vious ECMO training study demonstrating that military   may skew our results. However, attendance at these courses
          medical personnel can be trained to perform ECMO.  Our   offered to SOST personnel may also be representative of the
                                                     16
          study expands on the literature by demonstrating that surgi-  skillsets of these medical providers. Sixth, given that the same
          cal teams can meet validation metrics and perform procedures   knowledge assessment was used before and after the course,
          on models on VV ECMO. Through knowledge assessments,   this learning effect and targeted retention of material could
          self- assessments, and validation testing of skills learned, this   be observed in the improvement in scores. Finally, we trained
          course demonstrates that SOSTs can be trained to safely and   12 SOST-qualified personnel; however, our training platform
          effectively cannulate for and manage VV ECMO. This study   may not be applicable to other surgical teams or non-surgical
          is a first step toward demonstrating that forward surgical   medical personnel. Validation of our course in other military
          teams possess the expertise to successfully accomplish initial     medical personnel is needed.
          training.

          Special Operations Forces (SOF)                    Conclusions
          Application of VV ECMO                             In a cohort of United States Air Force SOST personnel, using a
          VV ECMO is increasingly used to stabilize patients with se-  modified training curriculum and a 2-hour, hands-on validation
          vere thoracic injury with good results.  There is benefit to early   testing improved self-assessment and knowledge assessment
                                       9
          initiation of VV ECMO in trauma as part of a resuscitation   scores in performing VV ECMO. Given the rise of extracor-
          strategy to improve hypoxemia and hypercarbia and forward   poreal support use in the care of medical and trauma patients
          surgical teams can rapidly learn to employ VV ECMO in aus-  and possibility of PCC in the military population, forward VV
          tere  environments.   Thoracic  injuries  are  common  in both   ECMO training and sustainment should be studied further.
                         9
          blunt and penetrating trauma with survival rates as low as
          4.6%. 31,32  Blast injuries and penetrating thoracic trauma put   Author Contributions
          patients at particular risk of requiring operative intervention.    EKP performed literature review, study design, data collection
                                                         33
          Severe pulmonary injury and hemorrhage may require pneu-  and analysis, data interpretation, and writing. TR, JKW, SJ,
          monectomy or removal of the lung for hemorrhage control as   AEM, and DA performed study design and critical revision,
          part of a damage control strategy. 34,35  VV ECMO can provide   BST, RK, MK, and TMS performed data interpretation, writ-
          stabilization of these patients, allowing for transportation out   ing, and critical revision, SMG performed study design, data
          of theater. Future conflicts requiring PCC and multidomain   analysis, data interpretation, and critical revision.
          transports could use expanded extracorporeal support to im-
          prove patient survival. SOF are at particular risk for severe   Disclosures
          injury and delayed transport given austere operational envi-  The authors have no potential competing interests to disclose.
          ronments. Medical personnel that support these personnel can   This work was presented at the 34th Extracorporeal Life Sup-
          improve outcomes through research and clinical innovation.   port Organization Conference Seattle,  WA Sept 28–Oct 1,
          In addition to device innovation and study of novel clinical ap-  2023.
          plications, clinician training is an important part of expanded
          VV ECMO implementation. Our study is the first step in this   Disclaimer
          development and demonstrates that SOSTs that support SOF   The views expressed in this material are the views of the au-
          can be trained in VV ECMO.
                                                             thors, and do not reflect the official policy or position of the

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