Page 55 - JSOM Fall 2022
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              compressive forces on the treated limb.  The general con­  Implications of ST Findings in
              sensus amongst a majority  of leading trauma researchers  is   Context of Wrap-Based Tourniquets
              that the benefits of prehospital tourniquet use far outweigh   The findings of this study demonstrate the functional feasibil­
              the risks of tourniquet­associated sequelae. 2,3,6,35  Nonetheless,   ity of the minimally elastic, wrap­based ST tourniquet design.
              decreasing the risk of those sequelae is desirable for improving   While both ST and Esmarch tourniquets are tightened around
              patient outcomes. The finding that the 10.2­cm­wide, mini­  a limb by successive circumferential wraps while stretched
              mally elastic, adhesive wrap–based ST can deliver quick, effec­  under pull­tension, there are important differences between
              tive arterial occlusion with completion pressures lower than   these devices. Beyond the presence of an adhesive and release
              the windlass­based CAT addresses an important concern asso­  coating on its opposing surfaces, the ST most notably differs
              ciated with emergency­use tourniquets.             from the Esmarch tourniquet in that it is minimally elastic.
                                                                 This structural difference is important as a study on canines
              While  the  10.2­cm­wide  ST  was  found  to  deliver  mid­thigh   of  a 8.5­cm­wide,  shape­stabilized  pneumatic  cuff  and an
              tourniquet completion pressures lower than the 3.8­cm­wide   8­cm­wide Esmarch tourniquet reported that the tissue pres­
              CAT, the data from this study do not provide direct evidence   sure profile decreases from the midpoint outward to the edges
              about the origin(s) of this phenomenon. The characterization   of a tourniquet, but to a substantially greater extent in the
              of the relationship between tourniquet width and delivered   Esmarch device.  Furthermore, the Esmarch tourniquet was
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              limb compression, occlusion pressure, tissue pressure profile,   observed to show pressure concentration at the center of the
              and other parameters has been an active area of research for   limb, and such a pressure concentration is expected to increase
              many years. 15,28,33,36,37  Some progress has been made in this area   risk of tourniquet­associated tissue damage. Thus, while
              through the use of pneumatic tourniquet pressure data, but   a wider, elastic wrap might be presumed to present a lower
              a mathematical relationship which accurately predicts occlu­  risk of tissue injury than a narrower non­elastic tourniquet,
              sion pressures for nonpneumatic designs remains elusive. 28,37    this may not be the case. The laboratory validation of the ST
              For example, a study by Wall et al. reported a 3.8­cm­width,   suggests the feasibility of future studies investigating the lo­
              nonelastic  strap, rachet­based  tourniquet achieving  comple­  cal tissue pressure profiles of similarly sized, minimally elastic
              tion pressures similar to a 10.2­cm­width, elastic, wrap­based   and elastic wrap–based tourniquets. Such studies may provide
              tourniquet in certain cases, while the 3.8­cm­wide, nonelastic   a better understanding of the complex interplay between the
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              strap CAT generally achieved occlusion at higher pressures.    width and elasticity of tourniquets and their resulting capacity
              Therefore, attributing the observed differences between ST   to safely distribute pressure while delivering arterial occlusion.
              and CAT completion pressures specifically to their differing
              widths without additional supporting data is inadvisable. This   Limitations
              is because these two tourniquets also differ meaningfully in   The mid­thigh tourniquet application site was selected based
              their structure and composition as well as how each is tight­  on the expectation that it would require greater pressures to
              ened and secured.                                  achieve arterial occlusion than an alternate site of smaller limb
                                                                 circumference, and thus the mid­thigh was also expected to
              Tourniquet Application and                         allow for  greater  experimental  resolution  of any  differences
              Human Use Factors                                  in occlusion pressures, and by extension, completion pres­
              Despite substantial differences between the design, composi­  sures. However, the pressure required for a given tourniquet
              tion, and application process for the ST and CAT, it is im­  to achieve occlusion is known to be impacted not only by
              portant to note that no statistically significant differences   tourniquet configuration and limb circumference, but also by
              were observed in their times to occlusion and completion or   hemorrhage location, muscle tension, arterial depth, and other
              in their ease­of­use ratings. This finding suggests that the ad­  anatomical characteristics which were not explored in this
              hesive wrap–based design of the ST does not negatively impact   study. 15,28,33,40  Thus, it is unknown if an analogous difference
              its ability to efficiently deliver hands­free hemorrhage control   would be observed between the completion pressures of the
              relative to the CAT.                               CAT and ST if the study were repeated at another limb site.

              While the physical design of a tourniquet can provide a lower   This  study  was  conducted  in  a  controlled  laboratory  setting
              limit for the time and number of steps required for it to be   on perfused cadavers with similar demographics and not on
              effectively deployed, human factors such as intuitiveness of   living patients. While the CAT and ST were applied at an ap­
              design, ease of handling, and the complexity of each appli­  propriate, limb extremity site in a process similar to how each
              cation and adjustment step can critically influence how effi­  might be used on live patients, differences remain between the
              ciently a tourniquet delivers hemostasis for a real­world user.   cardiovascular output and tissue response of a living patient
              This aspect of tourniquet use was highlighted by Baruch et al.   compared with that of a perfused cadaver. As a result, a future
              who reported that a user’s ability to effectively apply a tourni­  study of the pressure required for the CAT and ST to deliver ar­
              quet to a mannequin limb model can be impacted by the user’s   terial occlusion in the limbs of healthy human volunteers would
              level of understanding of a specific tourniquet’s mechanism of   provide valuable context for the findings reported herein.
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              action.  While the CAT and several similar, windlass­based
              tourniquets have been widely used for many years, the same   While the experimental protocol for this study was designed
              cannot be said of the minimally elastic, adhesive wrap­based   to simulate the emergency treatment of serious arterial hem­
              ST tourniquet. Therefore, while the ST somewhat resembles   orrhage, it nonetheless did not fully replicate the real­world
              an Esmarch tourniquet, experienced tourniquet users who are   conditions in which a tourniquet is typically used. As previ­
              unfamiliar with the ST would be expected to require practice   ously noted, the efficacy of a tourniquet is a function of both
              to achieve occlusion times, application speeds, and success   its inherent operational capabilities as well as user­related fac­
              rates at parity with more familiar tourniquets.    tors such as intuitiveness of design, complexity of application,
                                                                 and ease of adjustment. Therefore, a focused investigation of

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