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Blood Product Administration During Transport

                     Throughout the US Africa Command Theater of Operation


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                 Steven G. Schauer, DO, MS *; Jason F. Naylor, DSc, PA-C ; Andrew D. Fisher, MD, LP ;
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                    Darren G. Hyams, MD ; Brandon M. Carius, DSc, PA-C ; Mireya A. Escandon, BS ;
                              Carlissa D. Linscomb, BS ; Harry McDonald, PhD, MS, SBB ;
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                                    Andrew P. Cap, MD, PhD ; James Bynum, PhD    10
          ABSTRACT
          Background: United States Africa Command (US AFRICOM)   Introduction
          is one of six US Defense Department’s geographic combatant   During the recent wars in Iraq and Afghanistan, approximately
          commands and is responsible to the Secretary of Defense for   90% of US military Servicemembers’ deaths occurred in the
          military relations with African nations, the African Union,   prehospital setting, and nearly 25% of deaths were second-
          and African regional security organizations. A full-spectrum   ary to potentially survivable injury, among which >90% was
          combatant command, US AFRICOM is responsible for all   related to hemorrhage.  The deployed US military medical
                                                                               1–3
          US Department of Defense operations, exercises, and security   system implemented strategies for rapid casualty evacuation to
          cooperation on the African continent, its island nations, and   surgical facilities and early hemostatic resuscitation of severely
          surrounding  waters.  We  seek  to characterize  blood product   injured patients to optimize survival.  Published data demon-
                                                                                         4–7
          administration within AFRICOM using the in-transit visibility   strate prehospital administration of blood products, and early
          tracking tool known as TRAC2ES (TRANSCOM Regulating   surgical intervention improved combat casualty outcomes. 8–12
          and Command & Control Evacuation System). Methods: We   The “Golden Hour” evacuation policy and damage control re-
          performed a retrospective review of TRAC2ES medical evac-  suscitation (DCR) paradigm, however, owes its success in part
          uations from the AFRICOM theater of operations conducted   to a military trauma system supported by established medical
          between  1  January  2008  and  31  December  2018.  Results:   and logistical infrastructure. 13,14
          During this time, there were 963 cases recorded in TRAC2ES
          originating within AFRICOM, of which 10 (1%) cases re-  The US Africa Command (AFRICOM) manages military op-
          ceived blood products. All patients were males. One was a   erations across a continent that is 3 times larger than the con-
          Department of State employee, one was a military working   tinental United States with immature medical and logistical
          dog, and the remainder were military personnel. Of the ten   systems. 15,16  Increasing numbers of US military forces deploy
          humans, seven were the result of trauma, most by way of gun-  to AFRICOM and published data demonstrate few battle in-
          shot wound, and three were due to medical causes. Among   juries. However, such injuries are predominantly from pene-
          human subjects receiving blood products for traumatic inju-  trating trauma and require evacuation out of theater to the
          ries, a total of 5 units of type O negative whole blood, 29   US military hospital in Landstuhl, Germany. 17,18  Adherence
          units of packed red blood cells (pRBCs), and 9 units of fresh   to the “Golden Hour” standard is not feasible throughout
          frozen plasma (FFP) were transfused. No subjects underwent   all of AFRICOM, which should prompt emphasis of remote
          massive transfusion of blood products, and only one subject   DCR principles to optimize outcomes. 19–21  It is unclear if he-
          received pRBCs and FFP in 1:1 fashion. All subjects survived   mostatic resuscitation is possible given the sheer geography
          until evacuation.  Conclusions: Within the TRAC2ES data-  of   AFRICOM and limited resources. However, freeze-dried
          base, blood product administration within AFRICOM was   plasma (FDP), warm fresh whole blood (WFWB), stored whole
          infrequent, with some cases highlighting lack of access to ade-  blood (SWB), and cold-stored low-titer group O whole blood
          quate blood products. Furthermore, the limitations within this   (CS-LTOWB) may be potential options. 22–27  To date, there a
          database highlight the need for systems designed to capture   little published data on hemostatic resuscitation of casualties
          medical care performance improvement, as this database is   within AFRICOM.
          not designed to support such analyses. A mandate for perfor-
          mance improvement within AFRICOM that is similar to that
          of the US Central Command would be beneficial if major im-  Goal of This Investigation
          provements are to occur.
                                                             We are seeking to describe blood product administration
          Keywords: prehospital; blood; Africa; prolonged field care;   throughout the AFRICOM theater of operations within the
          AFRICOM                                            TRAC2ES data repository.

          *Correspondence to 3698 Chambers Pass, JBSA Fort Sam Houston, TX 78234; or Steven.G.Schauer.mil@mail.mil
          1 MAJ Steven G. Schauer is affiliated with the US Army Institute of Surgical Research and the Brooke Army Medical Center of JBSA of Fort Sam
          Houston, TX, and the Uniformed Services University of the Health Sciences, in Bethesda, MD.  LTC Jason F. Naylor is affiliated with Madigan
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          Army Medical Center, Joint Base Lewis McChord, WA.  MAJ Andrew Fisher is affiliated with the Department of Surgery, University of New Mex-
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          ico School of Medicine, Albuquerque, NM, and the Medical Command, Texas Army National Guard, Austin, TX.  MAJ Darren G. Hyams and
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          5 Brandon M. Carius are affiliated with the Brooke Army Medical Center, JBSA Fort Sam Houston, TX.  Mireya A. Escandon,  Carlissa D.
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            Linscomb,  LTC Harry McDonald,  COL Andrew P. Cap, and  Dr James Bynum are affiliated with the US Army Institute of Surgical Research,
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          JBSA Fort Sam Houston, TX.
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