Page 125 - JSOM Summer 2020
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Fresh Whole Blood Collection and Transfusion at Point of Injury,
                       Prolonged Permissive Hypotension, and Intermittent REBOA


                 Extreme Measures Led to Survival in a Severely Injured Soldier—A Case Report



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                     Clayton J. Lewis, MD *; Matthew Nilan, DO ; Charles Srivilasa, MD ; Ryan Knight, MD ;
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                        Joseph Shevchik, DO ; Brad Bowen, ATP ; Ty Able, ATP ; Peter Kreishman, MD   8
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              ABSTRACT
              We present the case of a severely injured Special Operations   Case Presentation
              Servicemember whose care was remarkable for three unique
              interventions: the first use of a walking blood bank performed   While conducting combat operations in Afghanistan, a 33-
              at the point of injury, prolonged permissive hypotension, and   year-old active duty Ranger sustained a right-sided complex
              intermittent resuscitative endovascular balloon occlusion of   blast injury from an improvised explosive device.
              the aorta (REBOA).
                                                                 The Ranger’s injuries included massive soft tissue injury from
                                                                 the right costal margin to the right knee, right internal iliac
              Keywords: resuscitative endovascular balloon occlusion of   vein injury, right femoral head/neck fractures with significant
              the aorta (REBOA); intermittent REBOA; permissive hypo-  bone loss, right pelvis destruction  (both column right ace-
              tension; walking blood bank; buddy transfusion
                                                                 tabular fractures, comminuted ilium fracture with complete
                                                                 disruption of the sacroiliac joint, superior/inferior pubic rami
                                                                 fractures bilaterally), sigmoid colotomy, bilateral pneumotho-
                                                                 races, and mangled right upper extremity (RUE) with arterial
              Introduction
                                                                 injuries to the brachial, radial, and ulnar arteries. His Injury
              Since 2014, tactical combat casualty care (TCCC) guidelines   Severity Score was 66 (Figure 1).
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              have advocated for early resuscitation with whole blood,  and
              several studies have shown a survival benefit in trauma with   At point of injury, the Ranger medics immediately placed tour-
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              whole blood transfusion.  In 2018, Advanced Resuscitative   niquets on the right upper and lower extremities, while an im-
              Care (ARC) was introduced to supplement TCCC guidelines.   provised pelvic binder with a junctional tourniquet device was
              Based on the mortality associated with noncompressible torso   inflated over the right groin. Constant manual pressure to the
              hemorrhage  and  a  gap  in  prehospital  measures  to  control   casualty’s right groin and abdomen was maintained through-
              this, ARC promotes early whole blood administration and   out the entire treatment process. IV access was established in
              REBOA. 4                                           the left antecubital fossa and 1g of TXA was rapidly admin-
                                                                 istered. Needle decompressions were performed in all four
              Walking blood banks (WBBs), or the emergent collection and   authorized sites with the addition of a right-sided chest tube
              transfusion of fresh warm whole blood, is a well-established   (Figure 2). A total of 4 units of cold stored low-titer O whole
              contingency in current combat operations at established lev-  blood (CSWB) was administered to the casualty with the trans-
              els of care. The most forward recorded WBB was during a   fusion target of a palpable radial pulse. Due to ongoing hemor-
              well-coordinated assault on a small combat outpost where a   rhage, deteriorating mental status, the depletion of all CSWB,
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              provider  orchestrated  a  WBB  at  his  aid  station.   Numerous   and the inability to immediately evacuate the casualty because
              Special Operations organizations have protocols in place for   of ongoing enemy engagements, the Ranger group O low-titer
              far forward WBBs. 6–10  Until recently, there have been no re-  (ROLO) WBB was initiated. Three units of fresh warm group
              corded reports of a WBB performed at the point of injury.  O low-titer blood were collected from prescreened, co-located
                                                                 Rangers while the unit was actively engaged on target. Once
              We will be presenting a case of a severely injured Ranger who   collected, 2 units, along with calcium gluconate, were trans-
              received fresh whole blood at the point of injury. In addition,   fused awaiting medical evacuation. During evacuation to the
              this severely injured Servicemember’s care was remarkable for   forward resuscitative surgical team (FRST), an additional unit
              intermittent  REBOA  and prolonged prehospital  permissive   collected on target was transfused followed by two additional
              hypotension, ultimately leading to the patient’s survival.  units of CSWB from the CASEVAC aircraft.
              *Correspondence to clayton.j.lewis4.mil@mail.mil
              1 MAJ Lewis is affiliated with Evans Army Community Hospital, Fort Carson, CO.  MAJ Nilan is affiliated with Evans Army Community
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                Hospital, Fort Carson, CO.  MAJ Srivilasa is affiliated with C-STARS, St. Louis, MO.  LTC Knight is affiliated with 1/75th Ranger Regiment.
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              5 CPT Shevchik is 1/75th Ranger Regiment Battalion Surgeon.  SSG Brad Bowen is affiliated with 1/75th Ranger Regiment.  SGT Able is affiliated
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              with the 1/75th Ranger Regiment.  LTC Kreishman is affiliated with Madigan Army Medical Center, Joint Base Lewis-McChord, WA.
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