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Methods                                            affiliations, similar mechanisms of injury, similar theaters of
                                                             operations and similar composite injury severity scores (ISS),
          Data Acquisition                                   but less severe scores for the thorax body region (Table 1).
          We identified subjects as part of a larger descriptive study of   There was a trend toward worse AIS for the face region in
          ED interventions for trauma patients in Iraq and Afghanistan   the cricothyrotomy group but, conversely, a trend toward less
          using predefined search codes.  This is a retrospective review   severe scores for the abdomen. Survival to hospital discharge
                                  12
          of prospectively collected data within the registry. We searched   rates were similar (Table 1). When using a binary cutoff of AIS
          our data set for all subjects who had a documented SGA de-  3 or greater (serious) for the head, the cricothyrotomy group
          vice or cricothyrotomy performed as the sole documented   had a higher rate of serious head injuries (67.5%, n = 131
          airway intervention before reaching the ED at a combat sup-  versus 45.5%, n = 10, p = .0393). When applying the same
          port hospital (CSH) or forward surgical team (FST). We ex-  binary measurement to the face, we were unable to detect a
          cluded subjects if they had more than one airway intervention   significant difference (4.6%, n = 9 versus 4.6%, n = 1, p =
          documented.                                        .984). When documented in the prehospital setting, median
                                                             GCS scores were similar for the two groups (median 3 [IQR
          The US Army Institute of Surgical Research regulatory office   3–6], n = 95 versus median 3 [IQR 3–7.5], n = 20, p = .591).
          reviewed protocol H-16-005 and determined it was exempt   We also found no difference for emergency department arrival
          from institutional review board oversight. We obtained only   GCS (3 [3–5.5], n = 188 versus 3 [3–5.25], n = 21, p = .469).
          deidentified data.
                                                             Regression Analyses
          Department of Defense Trauma Registry Description  On univariable analysis, the odds ratio of survival was similar
          The Department of Defense Trauma Registry (DODTR), for-  for SGA versus cricothyrotomy (1.20, 95% CI 0.49–2.94). We
          merly known as the Joint Theater Trauma Registry (JTTR), is   then performed a series of multivariable analyses controlling
          the data repository for DoD trauma-related injuries. 13,14  The   for confounders comparing SGA versus cricothyrotomy. When
          DODTR includes documentation regarding demographics,   controlling for injury scores by body region, the odds ratio
          injury-producing incidents, diagnoses, treatments, and out-  was not significant (OR 1.14, 0.42–3.10). When controlling
          comes of injuries sustained by US/non-US military and US/  for the presence of a serious head injury (AISBR1 3 or greater,
          non-US civilian personnel in wartime and peacetime from the   binary), the odds ratio was not significant (OR 1.06, 0.43–
          point of injury to final disposition. The DODTR comprises   2.65). No significant difference was noted when controlling
          all patients admitted to a Role 3 (fixed-facility) or FST with   for the mechanism of injury (OR 1.12, 0.45–2.76), patient cat-
          an  injury diagnosis  using  the  International  Classification  of   egory (OR 1.17, 0.47–2.90), or ED GCS (OR 1.64 0.62–4.30).
          Disease, Ninth Edition (ICD-9) between 800 and 959.9, near-
          drowning/drowning with associated injury (ICD-9 994.1) or
          inhalational injury (ICD-9 987.9) and trauma occurring within   Discussion
          72 hours from presentation. The registry defines the prehospi-  We evaluated combat casualties undergoing either cricothy-
          tal setting as any location prior to reaching an FST or a CSH   rotomy or SGA for advanced airway management in the pre-
          to include the Role 1 (point of injury, casualty collection point,   hospital setting. We found no difference in survival between
          battalion aid station) and Role 2 (temporary limited-capability   these two groups. This finding persisted on multiple regression
          forward-positioned hospital inside combat zone without sur-  analyses controlling for several factors, including injury scores
          gical support). The registry categorization scheme considers a   by body region.
          Role 2+ (or variant with surgical support) to be the ED.
                                                             Survival among patients undergoing either intervention
          Analysis                                           (54.6% for cricothyrotomy and 59.1% for SGA) was higher
          We performed all statistical analyses using Microsoft Excel   than previously published data. Studies on military prehospital
          (version 10, Redmond, WA) and JMP Statistical Discovery   airway interventions during the recent conflicts that reported
          from SAS (version 13, Cary, NC). We compared study vari-  mortality outcomes found a combined survival of 38.5% (15
          ables between subjects undergoing cricothyrotomy versus   of 39) for cricothyrotomy and 7.1% (1 of 14) for SGA. 15–18
          SGA placement using a Student t-test for continuous variables   The higher survival in our study may reflect exclusion from
          expressed as means with standard deviations, Wilcoxon rank   the DODTR of casualties who died before arrival to an FST
          sum test for ordinal variables expressed as medians and in-  or fixed-facility, whereas previous studies included those killed
          terquartile ranges (IQRs), and  χ  test for nominal variables   in action. Likewise, subjects in our study may have undergone
                                    2
          expressed as numbers and percentages. For binary outcomes,   stabilization at a battalion aid station or higher echelon of care,
          we used a logistic regression analysis to report odds ratios.  while previous reports primarily analyzed casualties evacuated
                                                             directly from the point-of-injury to an FST or fixed-facility.
                                                             Additionally, our study captured more exposures by compar-
          Results
                                                             ison: 194 versus 39 cricothyrotomies and 22 versus 14 SGA.
          Overall Analysis                                   Our findings suggest clinically appropriate cricothyrotomy
          During  the  study  period,  there  were  a  total  of  38,769  en-  and SGA may be equally efficacious prehospital advanced air-
          counters in the DODTR. Our predefined ED search codes   way interventions for the combat trauma population.
          captured 28,222 (72.8%) of those subjects. Within this data
          set, there were 194 (0.7%) subjects who underwent cricothy-  Overall, we found low incidence rates for both airway inter-
          rotomy versus 22 (0.1%) who underwent SGA placement as   ventions: 0.7% underwent cricothyrotomy, while 0.1% had a
          the sole documented means of airway intervention. Subjects   SGA inserted. These rates, however, are consistent with pub-
          in the cricothyrotomy group compared with the SGA group   lished military data. Multiple studies on US military prehos-
          had a lower median age, similar gender distribution, similar   pital cricothyrotomy describe incidence rates ranging 0.25%


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