Page 79 - JSOM Fall 2018
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the tourniquet, return of arterial flow was assessed by leaving   TABLE 3  Tourniquet Results: Median Scores for Pain and
              the probe in situ and monitoring Doppler waveform.  Application Time
                                                                          Variable          C-A-T        TMT
              End Point                                          Pain score,  median (IQR)  5 (4–7)     6 (3–8)
                                                                         a
              The application was considered successful if (1) ultrasound   Application time, median
              showed total occlusion of the popliteal artery; (2) the wind­  (IQR), seconds  37.5 (27–52)  35 (29–42)
              lass mechanism was locked into the plastic gate; (3) the study   C­A­T,  Combat  Application  Tourniquet;  IQR,  interquartile  range;
              participant deemed discomfort to be tolerable; and (4) arterial   TMT, Tactical Mechanical Tourniquet.
              flow resumed at tourniquet release.                a Pain was scored according to a numeric pain rating scale.
                                                                 TABLE 4  2 × 2 Contingency Table of Tourniquet Success or Failure
              Data Collection
                                                                                              Pain Not
              Demographic data on age and sex were collected. The time   Tourniquet  Pain Tolerated  Tolerated  Total
              taken to successfully apply each tourniquet (from first receiv­
              ing the tourniquet to arterial occlusion) and maximum pain   C­A­T   22            2         24
              scores on a 0 to 10 verbal numeric pain rating scale (0 = no   TMT   17            7         24
              pain, 10 = worst pain ever experienced) were also collected.   Total  39           9         48
              An answer (either C­A­T or TMT or same) was requested   C­A­T,  Combat  Application  Tourniquet;  TMT,  Tactical  Mechanical
              to two questions: “Which tourniquet is easiest to use?” and   Tourniquet.
              “Which tourniquet is the most painful?”
                                                                 The TMT was rated most painful by 11 volunteers, 10 vol­
              Non­normally distributed data are represented as a median   unteers rated the C­A­T most painful, and 3 volunteers rated
              and interquartile range (IQR). The Kruskal­Wallis test was   them equally painful. Thirteen volunteers rated the C­A­T
              used to compare medians of continuous, non­normally distrib­  easier to use, seven rated the TMT easier, and four thought
              uted, independent variables. P < .05 is considered significant.   they were equally easy to apply. A histogram of pain scores for
              Kurtosis calculations were performed to analyze for skewness.   each tourniquet system is shown in Figure 3. The pain scores
              Fisher exact test was used analyze 2 × 2 contingency tables   for the C­A­T were more tightly grouped around the median
              with two­tailed  p values for significance testing. Data were   score than were the TMT pain scores, which were more widely
              processed in Excel (Microsoft, www.microsoft.com).  distributed around the median of 6 out of 10.

                                                                 FIGURE 3  Pain score histogram for each tourniquet model.
              Results
              The 24 volunteers allowed testing on their collective total of
              48 lower limbs (Table 2). Times to application were positively
              skewed (kurtosis = 3.52). Pain scores were negatively skewed
              (kurtosis = 2.59).

              TABLE 2  Demographic Data for 24 Volunteers (N = 48 Limbs)
                         Volunteers              No. (%) a
              Demographics
                Male                              20 (83)
                Female                             4 (17)
                Age, median, IQR, years         34.5 (27–48)
              Tourniquets
                C­A­T tolerated                   22 (92)
                TMT tolerated                     17 (71)
              C­A­T,  Combat  Application  Tourniquet;  IQR,  interquartile  range;
              TMT, Tactical Mechanical Tourniquet.
              a Unless otherwise indicated.                      Pain description
                                                                 Volunteers described the pain from application of the TMT
              The C­A­T was applied successfully to 22 volunteers (92%),   during the study, although it was not a metric formally ex­
              and the TMT was successfully applied to 17 (71%). The time   plored in the methodology. Pain was experienced where the
              to reach complete arterial occlusion was a median of 37.5   circumferential  hook­and­loop strap met the plastic back
              (IQR, 27–52) seconds with the C­A­T, and 35 (IQR, 29–42)   plate. As tightening occurred, the strap was drawn across the
              seconds with the TMT. The 2.5­second difference in median   backplate nonuniformly, and the skin was pinched in this area.
              times was not significant (p = .589). The 1­in­10 difference in
              median pain score also was not significant (p = .656). Pain and   Discussion
              application time results are presented in Table 3.
                                                                 Efficacy
              When analyzed by a 2 × 2 contingency table (Table 4) consid­  In our study, the TMT was less effective during self­applica­
              ering success or failure of the tourniquet based on the toler­  tion at the mid thigh than was the C­A­T in healthy serving
              ance or intolerance of pain, the C­A­T was better tolerated.   military volunteers. This difference was not statistically signif­
              The difference, however, again failed to reach statistical signif­  icant either in terms of application time, median pain scores,
              icance (two­tailed p = 0.137).                     or success/failure scores. Furthermore, the contingency table

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