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of stabilizing and preparing casualties for strategic aero-  academies that provide processes of credentialing (and de-
                  medical evacuation (AE).                       velop certification guidelines). In the United States, the Ameri-
                                                                 can Society of Extracorporeal Technology and the American
                Role 3—Hospital Response Capability. A hospital response   Board of Cardiovascular Perfusion have developed minimal
                capability provides secondary health care at the theater   standards for perfusionists in clinical practice as a checklist,
                level. This role must provide all the capabilities of Role 2   monitoring significant events and parameters of each clinical
                and be able to conduct specialized surgery, care, and ad-  procedure.  The technician and advanced technician levels of
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                ditional services.                               practice can be learned by medics and assistants.

                Role 4—Definitive Hospital Response Capability. A defini-  The use of ECMO/ECLS in prehospital care on the battlefield
                tive hospital response capability offers the full spectrum of   is underestimated in the military theater. Advanced ECMO/
                definitive medical care that cannot be deployed to the the-  ECLS technology allows cardiopulmonary stabilization and
                ater or will be too time-consuming to be conducted in the   aeromedical evacuation for critically ill combatants with lung
                theater. Role 4 normally provides definitive care specialist   injuries.  It also occurs in casualty transportation from Role
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                surgical and medical procedures, reconstructive surgery,   3 to Role 4. The use of this device may be more wide rang-
                and rehabilitation                               ing. The deployment of ECMO/ECLS technology with trained
                                                                 specialists closer to the battlefield is possible and should be
              The organization of tactical field care and enhanced field care   explored in a far more aggressive and rapid fashion.
              rendered by combat lifesavers, combat medics, medics, phy-
              sicians, and their assistants firmly stands on these roles. But   ECMO has been already used to support trauma and burn
              where  would ECMO  fit  within this  paradigm—and  where   patients in hospital settings. There were reported applications
              would it be feasible to deploy, implement, and feed evidence   of ECMO in severe trauma patients with resistant cardio-
              back into the medical lessons learned system?      pulmonary failure and coexisting bleeding shock.  ECMO
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                                                                 therapy has proved to be a valuable option when conven-
              The Joint Theater Trauma System (JTTS) and Joint Theater   tional therapies for polytrauma/multitrauma patients with
              Trauma  Register  (JTTR)  were  developed  and  implemented   refractory cardiopulmonary failure and refractory shock
              by US military forces, using US civilian trauma system mod-  are insufficient.  Experiences in the application of ECMO
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              els with the intent of improving outcomes after battlefield in-  in burn patients with inhalation injuries have also been well
              jury.  The data from JTTR help to improve tactical algorithms   described. 25
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              and guidelines for higher combat casualty survival, based on
              evidence-based practice. Any new device, drug, or process sug-  There are many companies that produce heart–lung support
              gested for improving combat casualty survival should include   systems with various components (ECMO/ECLS) of all shapes
              the use of this register for benchmarking between old stan-  and sizes; as technology advances, these systems become smaller,
              dard procedures and new innovative ones, especially through   easier to use, and more versatile for the prehospital and austere
              the NATO Military Medical Center for Medical Excellence   environment. A perfect solution for our purpose is represented
              (MilMED COE) lessons learned process and information   by the CARDIOHELP System (Maquet Gettinge Group; https://
              sharing. The only way that a new intervention such as ECMO   www.maquet.com/int/products/cardiohelp-system/). This device
              could be discussed is through providing an evidence base via   can be easily carried by one person; it is small and lightweight
              these networks.                                    (310mm × 250mm × 430mm and about 10kg). It is rugged and
                                                                 comes with a battery and a wide range of power supply. The
              Life-saving interventions (LSIs) within the TCCC framework   system can operate with two fully charged lithium ion batteries
              are defined as advanced airway, needle or tube thoracostomy,   for at least 90 minutes. The necessary system components are
              tourniquet, and hypotensive resuscitation with Hetastarch or   a medical gas supply and cannulas. The CARDIOHELP sys-
              another agent.  An early and reasonable application of this   tem is designed for extracorporeal respiratory support and for
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              intervention should prevent potentially survivable causes of   simultaneous cardiovascular and respiratory support for up to
              death as based on warfighting morbidity data presented to the   30 days.
              Committee of Tactical Combat Casualty Care (CoTCCC). A
              combat lifesaver’s mission is to stabilize the casualty for the   Ambulatory ECMO on the Battlefield
              evacuation to the next appropriate level of care.  The com-  When ECMO/ECLS is applied out of the hospital, it can be
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              bat lifesaver is a bridge between the self-aid/buddy aid (first   called ambulatory ECMO/ECLS. We assume a positive effect
              aid) training given to all Soldiers during basic training and the   of ambulatory ECMO/ECLS on the survival of combatants
              medical training given to the combat medic.  Combat med-  wounded in combat. We in particular expect that ECMO/
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              ics are often first responders who triage, treat, and evacuate   ECLS can help in the following situations:
              the wounded from the frontlines of battle, many times with
              limited resources and in violent and austere environments.    •  Battlefield trauma, major hemorrhage/catastrophic bleed-
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              Combat medics face unconscionable challenges and obstacles   ing, and heart failure
              in providing care in the PFC phase; would ECMO be able to   •  Chemical attacks, lung injuries, and respiratory failure
              help save lives? Could FRC, still in preliminary workshop
              phases, be a place for ECMO? And where would the clinical   Guidelines
              governance remit of the CoSCCC and/or the CoERCCC ad-  Guidelines and clinical practice pathways should prevent time
              dress the concept of ECMO in the prehospital space?  delays and describe the process in detail to best serve the pa-
                                                                 tient. The draft of guidelines for the ECMO/ECLS use in cases
              Perfusionists are specialists who operate extracorporeal tech-  of severely wounded warfighters on the battlefield could be
              nology (ECMO/ECLS, CPB). There are societies, boards, and   listed as follows (Figure 2):

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