Page 94 - JSOM Winter 2017
P. 94
.gov/kbi/docs/media%20releases/U-47700%20Media%20 40. Pascoe PJ. Opioid analgesics. Vet Clin N Am Small Anim
Release.pdf. Accessed 3 November 2017. Pract. 2000;30:757–772.
22. O’Donnell JK, Halpin J, Mattson CL, et al. Deaths involving 41. Dohoo SE, Tasker RA. Pharmacokinetics of oral morphine
fentanyl, fentanyl analogs, and U-47700—10 States, July– sulfate in dogs: a comparison of sustained release and con-
December 2016. MMWR Morb Mortal Wkly Rep. 2017;66 ventional formulations. Can J Vet Res. 1997;61(4):251–255.
(43):1197–1202. 42. Prosser JM, Jones BE, Nelson L. Complications of oral expo-
23. Pathan H, Williams J. Basic opioid pharmacology: an update. sure to fentanyl transdermal delivery system patches. J Med
Br J Pain. 2012;6(1):11–16. Toxicol. 2010;6(4):443–447.
24. Freye E, Levy JV. Opioids in Medicine: A Comprehensive 43. Streisand JB, Zhang J, Niu S, et al. Buccal absorption of fen-
Review on the Mode of Action and the Use of Analgesics in tanyl is pH-dependent in dogs. Anesthesiology. 1995;82(3):
Different Clinical Pain States. Dordrecht, the Netherlands: 759–764.
Springer; 2008. 44. Garrett ER, Gürkan T. Pharmacokinetics of morphine and
25. Offermanns S. Encyclopedia of Molecular Pharmacology. its surrogates, IV: Pharmacokinetics of heroin and its derived
2nd ed. New York, NY: Springer-Verlag Berlin Heidelber; metabolites in dogs. J Pharm Sci. 1980;69(10):1116–1134.
2008. 45. Blankstein A, Connor T. K-9 dogs overdose on fentanyl, drug
26. Opioid (narcotic). opioid (narcotic)—Memidex dictionary/the- that killed Prince. NBCNews.com. https://www.nbcnews.
saurus. http://www.memidex.com/opioid-narcotic#etymology. com/news/us-news/k-9-dogs-overdose-fentanyl-drug-killed
Accessed 3 November 2017. -prince-n687611. 28 November 2016. Accessed 6 November
27. Hemmings HC. Egan TD. Pharmacology and Physiology for 2017.
Anesthesia: Foundations and Clinical Application. Philadel- 46. Llera RM, Volmer PA. Toxicologic hazards for police dogs in-
phia, PA: Elsevier Saunders; 2013. volved in drug detection. J Am Vet Med Assoc. 2006;228(7):
28. Kukanich B, Clark TP. The history and pharmacology of fen- 1028–1032.
tanyl: relevance to a novel, long-acting transdermal fentanyl 47. Pace NL, Parrish RG, Lieberman MM, et al. Pharmacokinet-
solution newly approved for use in dogs. J Vet Pharmacol ics of naloxone and naltrexone in the dog. J Pharmacol Exp
Ther. 2012;35(suppl 2):3–19. Ther. 1979;208(2):254–256.
29. Volmer PA. Recreational drugs. In: Peterson ME, Talcott PA, 48. Wermeling DP. A response to the opioid overdose epidemic:
eds. Small Animal Toxicology. 3rd ed. St. Louis, MO: Elsevier naloxone nasal spray. Drug Deliv Transl Res. 2013;3(1):63–74.
Saunders; 2013:323–326. 49. Plumb DC. Veterinary Drug Handbook. 8th ed. Stockholm,
30. Freise KJ, Newbound GC, Tudan C, et al. Naloxone rever- WI: PharmaVet Inc.; 2015.
sal of an overdose of a novel, long-acting transdermal fen- 50. Centers for Disease Control and Prevention. Notes from
tanyl solution in laboratory Beagles. J Vet Pharmacol Ther. the Field: Acetyl fentanyl overdose fatalities—Rhode Island,
2012;35(suppl 2):45–51. March–May 2013. https://www.cdc.gov/mmwr/preview/mm
31. Hofmeister EH, Herrington JL, Mazzaferro EM. Opioid dys- wrhtml/mm6234a5.htm. 30 August 2013. Accessed 7 No-
phoria in three dogs. J Vet Emerg Crit Care. 2006;16:44–49. vember 2017.
32. KuKanich B, Papich M. Opioid analgesic drugs. In: Riviere J, 51. McEvoy M. Naloxone: Drug Whys – A comprehensive exam-
Papich M, eds. Veterinary Pharmacology and Therapeutics. ination of naloxone uses, pharmacology, pharmacokinetics,
9th ed. Ames, IA: Wiley-Blackwell; 2009:301–336. administration routes and dosing. 2015. https://www.ems1
33. US Drug Enforcement Administration. Fentanyl—a brief- .com/opioids/articles/18922048-Naloxone-Drug-Whys/. Ac-
ing guide for first responders. https://www.dea.gov/druginfo cessed 30 October 2017.
/fentanyl.shtml. Accessed October 20, 2017. 52. Smith K, Hopp M, Mundin G, et al. Low absolute bioavail-
34. The Interagency Board. Recommendations on selection and use ability of oral naloxone in healthy subjects. Int J Clin Phar-
of personal protective equipment and decontamination prod- macol Ther. 2012;50(5):360–367.
ucts for first responders against exposure hazards to synthetic 53. Merlin MA, Saybolt M, Kapitanyan R, et al. Intranasal nal-
opioids, including fentanyl and fentanyl analogues. https:// oxone delivery is an alternative to intravenous naloxone for
www.interagencyboard.org/. Accessed 20 October 2017. opioid overdoses. Am J Emerg Med. 2010;28(3):296–303.
35. Dumonceaux GA, Beasley VR. Emergency treatments for po- 54. Krieter P, Chiang N, Gyaw S, et al. Pharmacokinetic proper-
lice dogs used for illicit drug detection. J Am Vet Med Assoc. ties and human use characteristics of an FDA-approved intra-
1990;197(2):185–187. nasal naloxone product for the treatment of opioid overdose.
36. Micieli F, Santangelo B, Napoleone G, et al. Intranasal fen- J Clin Pharmacol. 2016;56(10):1243–1253.
tanyl for acute severe pain episodes control in a dog. Vet An- 55. Robinson A, Wermeling DP. Intranasal naloxone adminis-
aesth Analg. 2017. doi:10.1016/j.vaa.2017.06.003 tration for treatment of opioid overdose. Am J Health Syst
37. Micieli F, Santangelo B, Reynaud F, et al. Sedative and car- Pharm. 2014;71(24):2129–2135.
diovascular effects of intranasal or intramuscular dexmedeto- 56. Dowling J, Isbister GK, Kirkpatrick CM, et al. Population
midine in healthy dogs. Vet Anaesth Analg. 2017. doi:http:// pharmacokinetics of intravenous, intramuscular, and intrana-
dx.doi.org/10.1016/j.vaa.2016.08.009 sal naloxone in human volunteers. Ther Drug Monit. 2008;
38. Liu Y, Sun J, Zhang X, et al. Pharmacokinetic and absolute 30(4):490–496.
bioavailability study of naloxone hydrochloride nasal sprays.
Chin J New Drugs. 2010;19(8):718–728.
39. Al-Bagdadi F. The integument. In: Evans HE, de Lahunta A,
eds. Miller’s Anatomy of the Dog. 4th ed. St. Louis, MO: El-
sevier Saunders; 2013.
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