Page 21 - Journal of Special Operations Medicine - Winter 2015
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care are identified. Any voting member of the CoTCCC   projects that each member believed to be most impor-
              may propose a change to the current TCCC guide-    tant. Members were asked to consider the following in
              lines. The order in which changes are presented to the   selecting their Top 10 projects:
              CoTCCC is determined by the chairman, in consultation
              with the director of the JTS. The proposed change and   •  Will the project help to identify the causes of prevent-
              the evidence that supports it are compiled into a draft   able death on the battlefield?
              position paper. The paper is then discussed by the voting   •  Will the project help reduce preventable deaths on the
              members of the CoTCCC and by additional SMEs and     battlefield?
              liaisons from the Service medical departments, Combat   •  Will the project help reduce long-term disability?
              Command Surgeons’ staffs, other government agencies,   •  Is the intervention in the project feasible for prehospi-
              and allied nations that collectively compose the TCCC   tal care providers?
              Working Group. This review of proposed changes is ac-  •  What other methods to accomplish the desired effect
              complished either at meetings or via teleconference. Once   for the casualty are currently available?
              the proposed change has been reviewed and items of con-  •  How long would the project take to complete?
              tention have been discussed and addressed, the change is   •  How much will the project cost?
              reworded to reflect the consensus views and opinions pre-  •  How much will the new equipment or medication
              sented during the review process, and the position paper   cost to field?
              is revised and distributed. An electronic vote is then con-  •  What is the likelihood of successful completion of the
              ducted among the 42 voting members of the CoTCCC.    project?

              Once the proposed change is approved by the CoTCCC   The following list contains the Top 10 priorities for bat-
              and, subsequently, by the director of the JTS, the change   tlefield trauma care RDT&E as established by the votes
              paper is finalized and submitted to the US Army Institute   of the CoTCCC.
              of Surgical Research (USAISR) for publication approval.
              After approval, the TCCC change papers are published   1. Explore all options to make a US Food and Drug
              in the Journal of Special Operations Medicine. Interim   Administration (FDA)-approved dried plasma product
              change notices are sent out to a TCCC distribution group   available for all US Military Combat medical providers.
              and posted on several websites that post TCCC mate-  This product should be able to be transfused to casual-
              rial as soon as the paper is approved by USAISR and the   ties of any blood type, should be able to withstand the
              training slides needed to train the change have been de-  temperatures encountered in military prehospital set-
              veloped. The Prehospital Trauma Life Support textbook   tings, should have a long shelf life, and should not be
              is updated every 3–4 years and new changes are also re-  packaged in breakable containers.
              flected in each updated version of the PHTLS textbook.
              The TCCC change papers for 2013 through 2015 are in-  Freeze-dried plasma (FDP) was identified at the Janu-
              cluded in the references for this article. 12,18–25  ary 8–9, 2011, USAISR Medical Research and Materiel
                                                                 Command Fluid Resuscitation Conference as the most
              Each of the TCCC change papers has a section in which   promising near-term fluid for damage-control resuscita-
              additional research, development, test, and evaluation   tion in circumstances when Special Operations Forces
              (RDT&E) items of interest that emerged during the dis-  (SOF) medics or other Combat medical personnel must
              cussions of the proposed change are noted. These re-  provide casualty care in remote locations where evacua-
              search items are believed by the authors of that paper to   tion may be delayed for several hours or days. FDP was
              be of potential benefit to future CoTCCC decisions in   recommended as a top research priority by the SMEs at
              that aspect of prehospital trauma care. These potential   this conference. 30
              research items were compiled and placed into a consoli-
              dated list of potential RDT&E topics. Also included in   As a resuscitation fluid, plasma restores fibrinogen and
              this list are research priorities identified by the CoTCCC   other hemostatic factors, as well as volume, in contrast
              and endorsed by the DHB in previous years, 26,27  and   to crystalloids and colloids, which restore volume with-
              RDT&E issues noted in the two Joint Training System   out any hemostatic factors and, thus, contribute an iat-
              (JTS)/US Central Command assessments of prehospital   rogenic component to trauma-associated coagulopathy.
              trauma care in Afghanistan. 28,29                  Early administration of plasma to casualties in hem-
                                                                 orrhagic shock is an essential part of the JTS damage
                                                                 control resuscitation (DCR) strategy.  DCR is also now
                                                                                                31
              Current CoTCCC RDT&E Recommendations
                                                                 widely used in the US civilian sector. 32–35
              In April 2015, voting members of the CoTCCC were
              provided  with  the  compiled  list  of  116  proposed   Plasma was preferred over crystalloids and colloids in
              RDT&E projects and asked to identify the 10 research   the recent TCCC review of resuscitation fluids.  FDP
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