Page 91 - Journal of Special Operations Medicine - Spring 2014

Table 3 HR in beats/min.
2 min 4 min 6 min 8 min
Before After after after after after
Group bleed bleed p Value Hextend p Value Hextend p Value Hextend p Value Hextend p Value
Between Between Between Between Between
IO 96 ± 11 99 ± 25 IO vs. IV 94 ± 23 IO vs. IV 85 ± 18 IO vs. IV 89 ± 9 IO vs. IV 88 ± 17 IO vs. IV
(p = .74) (p = .78) (p = .45) (p = .49) (p = .45)
Between *Between *Between *Between *Between
IV 89 ± 4 87 ± 9 IO vs. none 85 ± 9 IO vs. none 85 ± 7 IO vs. none 86 ± 7 IO vs. none 86 ± 6 IO vs. none
(p = .051) (p = .003) (p = .006) (p = .007) (p = .001)
Between *Between *Between *Between *Between
IV and IV and IV and IV and IV and
None 97 ± 12 99 ± 39 98 ± 26 99 ± 11 95 ± 17 104 ± 6
none none none none none
(p = .09) (p = .006) (p = .033) (p = .035) (p = .005)
Note: *Significant at .05.

Table 4 MAP in mmHg.
2 min 4 min 6 min 8 min
Before After after after after after
Group bleed bleed p Value Hextend p Value Hextend p Value Hextend p Value Hextend p Value
Between Between Between Between Between
IO 77 ± 15 35 ± 11 IO vs. IV 45 ± 8 IO vs. IV 53 ± 9 IO vs. IV 57 ± 9 IO vs. IV 58 ± 9 IO vs. IV
(p = .46) (p = .40) (p = .20) (p = .47) (p = .37)
Between *Between *Between *Between *Between
IV 81 ± 13 45 ± 9 IO vs. none 58 ± 7 IO vs. none 67 ± 10 IO vs. none 70 ± 10 IO vs. none 72 ± 10 IO vs. none
(p = .75) (p = .011) (p = .000) (p = .000) (p = .001)
*Between *Between *Between *Between *Between
IV and IV and IV and IV and IV and
None 81 ± 7 37 ± 16 36 ± 15 38 ± 16 40 ± 13 43 ± 11
none none none none none
(p = .029) (p = .001) (p = .000) (p = .000) (p = .000)
Note: *Significant at .05.

Hextend and Time of Administration and Hemodynamics in Swine Model 83
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