Page 64 - ATP-P 11th Ed

Table 11 TCCC Antibiotics TCCC Antibiotics
SECTION 1 Moxifloxacin (Avelox ) Administer 400mg PO daily for 10 days
®
Administer 1g daily IV/IO/IM for 10 days
®
Ertapenem (Invanz )
IV/IO to PO transition When transitioning from Ertapenem to Moxifloxacin, begin
Moxifloxacin immediately after the final dose of Ertapenem for
antibiotic overlap
Table 12 Alternative Antibiotics
(used if supplies of TCCC antibiotics are limited, or as directed by medical control)
Alternate Antibiotics
Good Better Best
Soft Tissue Injury Cefalexin PO or Cefazolin IM/IV/IO Moxifloxacin PO or
Bactrim DS PO Ertapenem IV/IO
Topical: Bacitracin Topical: Mupriocin
Suspected MRSA Topical: Mupirocin Ertapenem IV/IO Moxifloxacin PO or
Ertapenem IV/IO +
Vancomycin
Open Fx (I/II) Beta-lactam Allergy: Cefazolin IV/IO Ertapenem IV/IO or
Clindamycin IV/IO Moxifloxacin PO
Open Fx (III) no Beta-lactam Allergy: Ceftriaxone IV/IO Ertapenem IV/IO or
contamination Clindamycin IV/IO + Moxifloxacin PO
Levofloxacin IV/IO
Open Fx (III) soil or Beta-lactam Allergy: Ceftriaxone IV/IO + Ertapenem IV/IO or
fecal contamination Levofloxacin IV/IO + Metronidazole IV/IO Moxifloxacin PO
Metronidazole IV/IO
Penetrating Head Ceftriaxone IV/IO + Ertapenem IV/IO or
Injury Metronidazole IV/IO Moxifloxacin PO
Penetrating Chest Ertapenem IV/IO or
Injury Moxifloxacin PO
Penetrating Abdominal Ceftriaxone IV/IO + Ertapenem IV/IO or
Injury Metronidazole IV/IO Moxifloxacin PO
Burns (only when sepsis Ertapenem IV/IO or
is suspected) Moxifloxacin PO
Eye Injuries Erythromycin Ciprofloxacin drops (or if Moxifloxacin PO or
ointment/drops penicillin allergy) Ertapenem IV/IO
Dental Injuries Pen-VK or Clindamycin PO (or IV/ Moxifloxacin PO or
Augmentin PO IO) or if penicillin allergy Ertapenem IV/IO

54 SECTION 1 TACTICAL TRAUMA PROTOCOLS (TTPs) ATP-P Handbook 11th Edition 55