Page 151 - 2023 SMOG Digital

KETOROLAC Lactation Yes(Caution) Trade Name: Toradol
Class / Mechanism of Action
Nonsteroidal Anti-inflammatory Drug (NSAID)
Inhibits cyclooxygenase (COX 1 & 2) enzymes, which decreases production of prostaglandin precursors.
Provides antipyretic, analgesic, and anti-inflammatory action.
Indications
Labeled Indications: Short term management of moderate to severe acute pain as an opioid alternative.
Contraindications
• Hypersensitivity to ketorolac, aspirin, other NSAIDs, or any component of the formulation.
• High risk of bleeding, recent history of GI bleeding or perforation, known history of peptic ulcer
disease.
o Not for use as pain management for battlefield trauma patient!
• Suspected cerebrovascular bleeding Dizziness, Flushing, Diaphoresis, Tremor, Weakness
• Risk of renal failure secondary to volume depletion
• Concurrent use with other NSAIDs
Adverse Reactions / Precautions
• Inhibits platelet function
• Associated with an increased risk of adverse cardiovascular thrombotic events, including MI and
stroke
• May increase risk of GI irritation, inflammation, ulceration, bleeding, and perforation.
• May cause severe bronchospasm in patients with asthma
• May cause new onset hypertension or worsening of existing hypertension.
Dose and Administration: ADULT PEDIATRIC Always Reference BROSELOW Tape
Pain management (acute; moderately severe): Pain management (acute; moderately severe):
Patients ≥50 kg Adolescents >17 years only:
IM: • Refer to adult dose
• 15-30mg q6hr (maximum daily dose: 120mg)
IV:
• 15mg q6hr (maximum daily dose: 120mg)

Adults >65 years and/or adults <50 kg
IM:
• 15-30mg q6hr (maximum daily dose: 60mg)
IV:
• 15mg q6hr (maximum daily dose: 60mg)

151