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universal distribution. The William Beaumont Army Medical fluids in a forward deployed cold weather environment. Mil Med.
Center’s Institutional Review Board approved the study as an 2020;185(11-12):e2039-e2043. doi:10.1093/milmed/usaa213
exempt protocol (25-04) in November 2024. The information, 12. Fremon Scientific. Zip Thaw 202 System: User Manual. Fremon
content, and conclusions do not necessarily represent the of- Scientific; 2022. Accessed December 18, 2024. https://fremon
scientific.com/wp-content/uploads/2022/01/US-ZIPThaw-202-
ficial position or policy of William Beaumont Army Medical User-Manual-447000-UM-01-01-Rev.-09-Jan-2022.pdf
Center, Department of the Army, Defense Health Agency, or 13. Bischoff FZ, Davey W, Read B, et al. Non-inferiority of a new ad-
the U.S. Government. vanced dry plasma thawing system compared to leading standard
method: preservation of coagulation and anticoagulation proteins
Disclosures necessary for use in the clinic. J Clin Oncol. 2019;37(15_suppl):
The authors are military Servicemembers and employees of e14675–e14675. doi:10.1200/jco.2019.37.15_suppl.e14675
the U.S. Government. This work was prepared as part of their 14. Weichi Lab. Barkey Plasmatherm Instructions for Use. Weichi
Lab; 2022. Accessed December 18, 2024. https://www.weichilab.
official duties. Title 17, U.S.C., Section 105 provides that copy- com/upload/files/202410301714315494.pdf
right protection under this title is not available for any work 15. Kuta P, Melling N, Zimmermann R, Achenbach S, Eckstein R,
of the U.S. Government. Title 17, U.S.C., Section 101 defines Strobel J. Clotting factor activity in fresh frozen plasma after thaw-
a U.S. Government work as a work prepared by a military ing with a new radio wave thawing device. Transfusion. 2019;59
Servicemember or employee of the U.S. Government as part (5):1857–1861. doi:10.1111/trf.15246
of that person’s official duties. The authors have indicated 16. Beck KH, Schüftan C, Schubert D, Kretschmer V. Thawing of fresh
frozen plasma and virus-inactivated plasma – suitability of micro-
they have no financial relationships relevant to this article to wave oven. Infusionsther Transfusionsmed. 2002;29(6):313–317.
disclose. doi:10.1159/000068265
17. McCullagh J, Booth C, Lancut J, Platton S, Richards P, Green L.
Funding Every minute counts: a comparison of thawing times and haemo-
No funding was received for this work. static quality of plasma thawed at 37°C and 45°C using four dif-
ferent methods. Transfus Med. 2024;34(4):304–310. doi:10.1111/
tme.13061
References 18. Pinki SS, Mohan G, Rafi AM, Innah SJ, Thomas T. Rapid dry
1. Khawar H, Patel P, Stevens JB, Guzman N. Fresh Frozen Plasma plasma thawing system: an alternative to conventional thawing
(FFP). In: StatPearls. StatPearls Publishing; 2025. https://www. baths. Asian J Transfus Sci. 2017;11(2):147–150. doi:10.4103/
ncbi.nlm.nih.gov/books/NBK513347/ 0973-6247.214356
2. Fisher AD, Washburn G, Powell D, et al. “Clinical Practice Guide- 19. Chapman MP, Moore EE, Chin TL, et al. Combat: initial experi-
lines for Damage Control Resuscitation (DCR) in Prolonged ence with a randomized clinical trial of plasma-based resuscitation
Field Care (PFC).” Joint Trauma System. Published November 19, in the field for traumatic hemorrhagic shock. Shock. 2015;44(Sup-
2018. Accessed November 21, 2023. https://jts.health.mil/assets/ plement 1):63–70. doi:10.1097/shk.0000000000000376
docs/cpgs/Damage_Control_Resuscitation_PFC_01_Oct_2018_ 20. Food and Drug Administration (FDA). Microwave ovens. FDA.
ID73.pdf gov. Published October 12, 2023. Accessed December 18, 2024.
3. Helmer Scientific Incorporated. Plasma Thawing System Opera- https://www.fda.gov/radiation-emitting-products/resources-
tion Manual OuickThaw Models DH2 DH4 DH8. Helmer Sci- you-radiation-emitting-products/microwave-ovens
entific Incorporated; 2021. Accessed December 19, 2024. https:// 21. Tropitronics Incorporated. Microwave Plasma Defroster. Plas-
www.helmerinc.com/sites/default/files/2021-10/Plasma-Thawer- mathaw.com. Accessed December 19, 2024. http://plasmathaw.com/
Operation-Manual-360094-1.pdf benefitsspecs.html
4. Northern M, Baker J, Filak K, et al. “Clinical Practice Guideline 22. Sherman LA, Dorner IM. A new rapid method for thawing fresh
(JTS CPG) Austere Resuscitative and Surgical Care (ARSC).” frozen plasma. Transfusion. 1974;14(6):595–597. doi:10.1111/j.
Joint Trauma System. Published October 30, 2019. Accessed De- 1537-2995.1974.tb04585.x
cember 19, 2024. https://jts.health.mil/assets/docs/cpgs/Austere_ 23. Boström F, Ekemar L, Olsson D, Egberg N, Lundahl J. Rapid
Resuscitative_Surgical_Care_30_Oct_2019_ID76.pdf thawing of fresh-frozen plasma with radio wave-based thawing
®
5. Helmer Scientific Incorporated. Plasma Thawing: OuickThaw technology and effects on coagulation factors during prolonged
DH2 DH4 DH8 Brochure. Helmer Scientific Incorporated; 2015. storage at 4°C. Vox Sang. 2009;97(1):34–38. doi:10.1111/j.1423-
Accessed December 15, 2024. https://www.helmerinc.com/sites/ 0410.2009.01175.x
default/files/2024-10/380014-1%20Plasma%20Thawing%20 24. Churchill WH, Schmidt B, Lindsey J, Greenberg M, Boudrow S,
Brochure%20Oct2024.pdf Brugnara C. Thawing fresh frozen plasma in a microwave oven: a
6. Meledeo MA, Peltier GC, McIntosh CS, Corley JB, Bynum JA, comparison with thawing in a 37 degrees C waterbath. Am J Clin
Cap AP. Field-expedient thawing of fresh-frozen plasma. Transfu- Pathol. 1992;97(2):227–232. doi:10.1093/ajcp/97.2.227
sion. 2020;60 Suppl 3:S87-S95. doi:10.1111/trf.15652 25. Hirsch J, Bach R, Menzebach A, Welters ID, Dietrich GV, Hempel-
7. Hamilton Beach. Slow Cooker Use and Care Guide. Hamilton mann G. Temperature course and distribution during plasma
Beach; 2021. Accessed December 20, 2024. https://useandcares. heating with a microwave device. Anaesthesia. 2003;58(5):444–
hamiltonbeach.com/files/840290405.pdf 447. doi:10.1046/j.1365-2044.2003.03086.x
8. Hamilton Beach. Electric Kettle Use and Care Guide. Hamilton 26. Luff RD, Kessler CM, Bell WR. Microwave technology for the
Beach; 2020. Accessed December 20, 2024. https://useandcares. rapid thawing of frozen blood components. Am J Clin Pathol. 1985;
hamiltonbeach.com/files/840205103.pdf 83(1):59–64. doi:10.1093/ajcp/83.1.59
9. T-magitic. Travel Foldable Electric Kettle, Collapsible Food Grade 27. Rock G, Tackaberry E, Dunn J, Kashyap S. Rapid controlled
Silicone (600mL). Amazon; 2024. Accessed December 16, 2024. thawing of fresh-frozen plasma in a modified microwave oven.
https://www.amazon.com/Foldable-Electric-Collapsible- Transfusion. 1984;24(1):60–65. doi:10.1046/j.1537-2995.1984.
Silicone-Voltage%EF%BC%88600ml/dp/B07YRT7WJ9 24184122564.x
10. Anova Culinary. Anova Precision Cooker Pro. Anova Culi- 28. Sohngen D, Kretschmer V, Franke K, Pelzer H, Walker W. Thaw-
®
nary; 2023. Accessed December 15, 2024. https://anovaculinary. ing of fresh-frozen plasma with a new micro wave oven. Trans-
com/products/anova-precision-cooker-pro?srsltid=AfmBOopr fusion. 1988;28(6):576–580. doi:10.1046/j.1537-2995.1988.
W7mI97UF-_DofuVSoEfBNRr_Sso9Y-MFnFmsIidg7T4QQe87 28689059035.x
11. Vinceslio EM, Fayos Z, Bernadette A, Van Gent JM. Expedi-
tionary immersion circulating heating device: a promising tech- PMID: 40953408; DOI: 10.55460/MBFX-FHHR
nique for treating frostbit injuries and warming intravenous

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