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that autogenous grafts were more commonly used than syn-  importance of timing and the Golden Hour in arterial repair
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              thetic alternatives in the definitive repair of vascular trauma.    remains a relevant concept in modern combat operations.
              Despite its diminished popularity compared with autogenous   As the U.S. military shifts its focus from the GWOT to the
              grafts, synthetic grafts can provide an important limb salvage   realities of LSCOs, the military healthcare system must pro-
              strategy, especially when available soft tissue and autogenous   actively address the challenges of this dynamic environment.
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              conduits are reduced by multiple injuries.   With the many   The expectation of the Golden Hour, with short evacuation
              advancements made in synthetic graft composition since the   times, consistent air superiority, and the ability to transport to
              1950s, the decision between synthetic and autogenous grafts   hardstand, level II/III military treatment facilities is unrealistic
              is becoming increasingly dependent on surgeon preference,   for the military’s future challenges. Innovative, inter-service
              based on the localization of injury and patient condition. 8,9  medical solutions are required to position U.S. Forces to face
                                                                 large-scale conflict.
              Dr. Hughes described how arterial homografts did not remain
              viable beyond providing a “collagenous  framework,” while   Preparations for LSCOs are evident in the Navy’s latest class
              “the autogenous vein graft maintains a degree of cellular vi-  of expeditionary medical ships, including the recently chris-
                    4
              ability.”  His statements were supported by the significant   tened USNS Cody (EPF-14) and the newly authorized USNS
              incidence of amputation associated with homologous artery   Bethesda (EMS-1). These new ships may enhance the integra-
              grafts—a 33.3% reported amputation rate out of 48 patients   tion of afloat medical capabilities with land-based forward
                                 4
              treated with these grafts.  The ready availability of homografts   units, including field hospitals and SOF teams, as part of Joint
                                           4
              was likely their only notable benefit.  Currently, the use of   Force Operations. Future conflicts will likely present medical
              homo grafts has mostly been abandoned due to their suscep-  teams with nonlinear patient care challenges, requiring patient
                                                      10
              tibility to aneurysm and atheromatous degradation.  Recent   transport to make frequent stops on non-traditional platforms
              attempts using treated homografts, such as cryopreserved arte-  before receiving treatment. These fast medical ships can bridge
              rial homografts to reduce contamination and improve efficacy,   the gap between medical support and the POI in an unprece-
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              have demonstrated the need for further study.  Interestingly,   dented manner. Most importantly, they have the potential to
              these treated homografts have shown some benefit in infected   alleviate logistical challenges tied to transporting and stabiliz-
              fields as a temporizing maneuver for prosthetic grafting; how-  ing multiple casualties from littoral zones of operation, while
              ever, they do not appear to be effective substitutes for syn-  also bringing life-saving equipment and medical teams closer
              thetic or autogenous grafts in and of themselves. 10,12  Among   to the fight.
              the many advances made in vascular surgery, it appears that
              Dr. Hughes’ views on various procedures from the Korean War   Growing logistical capabilities are beneficial, but they remain
              remain consistent with current opinions on vascular repair.  constrained by medics’ abilities to address casualties quickly
                                                                 and effectively. Medics must move at the speed of the warf-
              Importance of Balancing Efficacy and Urgency       ighter and be prepared for prolonged field/casualty care. This
              in Vascular Treatment Amid Operational Reality     involves more than just attending a school or course; it re-
              Ligation as a method of treatment was less successful for limb   quires active involvement in hospital critical care units to learn
              salvage than direct anastomosis or grafting techniques. The leg-  not only the necessary skills but also the equipment require-
              acy of Dr. Hughes and fellow surgeons in Korea is a significant   ments for caring for combat casualties away from hardstand
              advancement of limb salvage provided by vascular reconstruc-  hospitals. One major skill—and logistical constraint—is the
              tion rather than ligation. 4,13  In today’s combat environment,   transfusion and resuscitation of the combat-wounded. Med-
              ligation remains an effective strategy in constrained combat   ics need to ensure they are confident and capable of provid-
              settings or where soft tissue, bony, and neurologic compromise   ing resuscitation as close to the POI as possible to improve
              of the distal limb preclude reasonable attempts to salvage. The   patient outcomes. Adequate medical capability demands not
              decision to ligate is based on the projected treatment efficacy.   only possessing the necessary skills, but also the initiative to
              In combat operations, available manpower, proximity to the   apply them.
              POI,  and triage  decisions  are  often  the  deciding  factors. As
              mentioned by Dr. Hughes, “ligation of major vessels will be   Medics and their command teams need to engage with their
              indicated in the presence of mass casualties requiring other   Army-supporting field hospital (FH) units to ensure that re-
              urgent surgery. While blood vessel repair was performed quite   suscitative and surgical care remains as close as possible to
              successfully in Korea, the situation was favorable to the extent   the injured casualty. In addition to these large FHs, profi-
              that the  main line of resistance  was  fairly stable, there  was   cient,  rapidly mobile surgical  teams, such  as  those in  the
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              good air coverage and fairly rapid evacuation.”  Despite the     Army’s 528th or Air Force Special Operations Surgical Teams
              immense benefit of vascular surgery, the fog of war remains   (SOSTs), will need to be utilized to bring surgery and greater
              a deciding factor in how a patient is treated. Every military   resuscitation capability even closer to the POI. Strategically
              element involved in patient transport, from the frontline medic   positioned Navy forces can provide shore-to-ship medical
              to the supporting ship or aircraft, should remember that action   platforms during larger scale operations as well as sea-based
              during the first few minutes of a casualty response will decide   tactical insertions and extractions, allowing for more rapid
              subsequent care in the hours to follow.            decompression of ground-based surgical teams and increasing
                                                                 capability across the Force. The U.S. Military’s recent focus on
                                                                 LSCOs will provide unique opportunities to plan inter-service
              Where Do We Go From Here?
                                                                 coordination of medical readiness. Ultimately, medics—partic-
              The LWF series serves to remind the Special Operations Forces   ularly those in SOF—need to own this planning component,
              (SOF) community, and all members of our medical corps team   acting as the liaison between the medical community and their
              that history is an ever-present teacher of battlefield lessons for   command teams, to ensure the best care for their wounded
              future conflicts. Drawing on the insights of Dr. Hughes, the   soldiers.

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