Page 52 - JSOM Summer 2024
P. 52

18.  Zhu  W, Ding  Y, Kong  W, Li  T, Chen H.  Docosahexaenoic   36.  Zhuang P, Wang W, Wang J, Zhang Y, Jiao J. Polyunsaturated fatty
             acid (DHA) provides neuroprotection in traumatic brain in-  acids intake, omega-6/omega-3 ratio and mortality: findings from
             jury models via activating Nrf2-ARE signaling.  Inflammation.   two independent nationwide cohorts. Clin Nutr. 2019;38(2):848–
             2018;41(4):1182–1193. doi:10.1007/s10753-018-0765-z  855. doi:10.1016/j.clnu.2018.02.019
          19.  Begum G, Yan HQ, Li L, Singh A, Dixon CE, Sun D. Docosa-  37.  Howell DR, Kirkwood MW, Laker S, Wilson JC. Collision and
             hexaenoic acid reduces ER stress and abnormal protein accu-  contact sport participation and quality of life among adolescent
             mulation and improves neuronal function following traumatic   athletes.  J Athl Train.  2020;55(11):1174–1180. doi:10.4085/
             brain injury. J Neurosci. 2014;34(10):3743–3755. doi:10.1523/  1062-6050-0536.19
             JNEUROSCI.2872-13.2014                          38.  Meyers L, Gamst G, Guarino A. Applied multivariate research.
          20.  Huang WL, King VR, Curran OE, et al. A combination of intra-  2nd ed. SAGE; 2017.
             venous and dietary docosahexaenoic acid significantly improves   39.  IBM. IBM Support: Clustering binary data with K-Means (should
             outcome after spinal cord injury. Brain. 2007;130(Pt 11):3004–  be avoided). Updated 16 April 2020. Accessed December 17, 2022.
             3019. doi:10.1093/brain/awm223                     https://www.ibm.com/support/pages/clustering-binary-data-
          21.  Liu ZH, Chen NY, Tu PH, et al. DHA Attenuates cerebral edema   k-means-should-be-avoided
             following traumatic brain injury via the reduction in blood-  40.  Naureen Z, Dhuli K, Medori MC, et al. Dietary supplements in
             brain barrier permeability. Int J Mol Sci. 2020;21(17):6291. doi:   neurological diseases and brain aging. J Prev Med Hyg. 2022;63
             10.3390/ijms21176291                               (2 Suppl 3):E174–E188. doi:10.15167/2421-4248/jpmh2022.63.
          22.  Pu H, Jiang X, Wei Z, et al. Repetitive and prolonged omega-3   2S3.2759
             fatty acid treatment after traumatic brain injury enhances long-  41.  Wood AHR, Chappell HF, Zulyniak MA.  Dietary and supple-
             term tissue restoration and cognitive recovery.  Cell Transplant.   mental long-chain omega-3 fatty acids as moderators of cognitive
             2017;26(4):555–569. doi:10.3727/096368916X693842   impairment and Alzheimer’s disease. Eur J Nutr. 2022;61(2):589–
          23.  Zhu W, Chi N, Zou P, Chen H, Tang G, Zhao W. Effect of docosa-  604. doi:10.1007/s00394-021-02655-4
             hexaenoic acid on traumatic brain injury in rats. Exp Ther Med.   42.  Patrick RP.  Role of phosphatidylcholine-DHA in preventing
             2017;14(5):4411–4416. doi:10.3892/etm.2017.5054    APOE4-associated Alzheimer’s  disease.  FASEB J.  2019;33(2):
          24.  Lust CAC, Mountjoy M, Robinson LE, Oliver JM, Ma DWL.   1554–1564. doi:10.1096/fj.201801412R
             Sports-related concussions and subconcussive impacts in athletes:   43.  Hanson JA, Lin Y-H, Dretsch MN, Strandjord SE, Haub MD,
             incidence, diagnosis, and the emerging role of EPA and DHA.   Hibbeln JR.  Whole food, functional  food, and supplement
             Appl Physiol Nutr Metab.  2020;45(8):886–892. doi:10.1139/  sources of omega-3 fatty acids and omega-3 HUFA scores among
             apnm-2019-0555                                     U.S. soldiers. J Functional Foods. 2016;23:167–176.
          25.  Higdon J, Drake VJ, Angelo G, Delage B, Jump DB. Essential fatty   44.  Sergeant S, Hugenschmidt CE, Rudock ME, et al. Differences in
             acids. Oregon State University. Reviewed June  2019.  Accessed   arachidonic acid levels and fatty acid desaturase (FADS) gene
             May, 6, 2023.  https://lpi.oregonstate.edu/mic/other-nutrients/  variants in African Americans and European Americans with di-
             essential-fatty-acids                              abetes or the metabolic syndrome. Br J Nutr. 2012;107(4):547–
          26.  Armstrong A, Anzalone AJ,  Pethick W,  et  al. An evaluation of   555. doi:10.1017/S0007114511003230
             omega-3 status and intake in Canadian elite rugby 7s players.   45.  Tanaka T, Shen J, Abecasis GR, et al. Genome-wide association
             Nutrients. 2021;13(11):3777. doi:10.3390/nu13113777  study of plasma polyunsaturated fatty acids in the InCHIANTI
          27.  Heileson JL, Elliott A, Buzzard JA, et al. A cross-sectional analysis   Study.  PLoS Genet.  2009;5(1):e1000338. doi:10.1371/journal.
             of whole blood long-chain omega-3 polyunsaturated fatty acids   pgen.1000338
             and its relationship with dietary intake, body composition, and   46.  Guo XF, Tong WF, Ruan Y, Sinclair AJ, Li D. Different metabolism
             measures of strength and power in collegiate athletes. J Am Nutr   of EPA, DPA and DHA in humans: a double-blind cross-over study.
             Assoc. 2023;42(1):94–100. doi:10.1080/07315724.2021.1995910  Prostaglandins Leukot Essent Fatty Acids. 2020;158:102033.
          28.  Heileson JL, McGowen JM, Moris JM, et al.  Body composi-  47.  Higdon J.  Micronutrient information center: essential fatty ac-
             tion, eicosapentaenoic acid, and vitamin D are associated with   ids. Linus Pauling Institute. Reviewed June 2019. Accessed De-
             Army Combat fitness test performance.  J Int Soc Sports Nutr.   cember 17, 2022. https://lpi.oregonstate.edu/mic/other-nutrients/
             2022;19(1):349–365. doi:10.1080/15502783.2022.2094717  essential-fatty-acids#essential-fatty-acid-deficiency
          29.  Peoples GE, Larsen P, Bowes HM, et al. The influence of a basic   48.  Guemez-Gamboa  A, Nguyen LN,  Yang H, et al. Inactivating
             military training diet on whole blood fatty acid profile and the   mutations in MFSD2A, required for omega-3 fatty acid trans-
             omega-3 index of Australian Army recruits. Appl Physiol Nutr   port in brain, cause a lethal microcephaly syndrome. Nat Genet.
             Metab. 2022;47(2):151–158. doi:10.1139/apnm-2021-0459  2015;47(7):809–813. doi:10.1038/ng.3311
          30.  Stark KD,  Van Elswyk ME, Higgins MR,  Weatherford CA,   49.  Kim S, Fenech MF, Kim PJ.  Nutritionally recommended  food
               Salem N, Jr. Global survey of the omega-3 fatty acids, docosa-  for semi- to strict vegetarian diets based on large-scale nutri-
             hexaenoic acid and eicosapentaenoic acid in the blood stream of   ent  composition  data.  Sci  Rep.  2018;8(1):4344.  doi:10.1038/
             healthy adults. Prog Lipid Res. 2016;63:132–152. doi:10.1016/j.  s41598-018-22691-1
             plipres.2016.05.001                             50.  Hanscom M, Loane DJ, Shea-Donohue T. Brain-gut axis dysfunc-
          31.  Barrett EC, McBurney MI, Ciappio ED. ω-3 fatty acid supplemen-  tion in the pathogenesis of traumatic brain injury. J Clin Invest.
             tation as a potential therapeutic aid for the recovery from mild   2021;131(12):e143777. doi:10.1172/JCI143777
             traumatic brain injury/concussion.  Adv Nutr.  2014;5(3):268–  51.  Celorrio M, Friess SH. Gut-brain axis in traumatic brain injury:
             277. doi:10.3945/an.113.005280                     impact on neuroinflammation.  Neural Regen Res.  2022;17(5):
          32.  Barringer N, Conkright W. Omega-3 fatty acid ingestion as a TBI   1007–1008. doi:10.4103/1673-5374.324839
             prophylactic. J Spec Oper Med. 2012;12(3):5–7. doi:10.55460/  52.  Ferrara M, Bertozzi G, Zanza C, et al.  Traumatic brain injury
             E1W8-7PLC                                          and gut brain axis: the disruption of an alliance. Rev Recent Clin
          33.  Harris WS, Del Gobbo L, Tintle NL. The omega-3 index and rela-  Trials. 2022;17(4):268–279. doi:10.2174/157488711766622062
             tive risk for coronary heart disease mortality: estimation from 10   2143423
             cohort studies. Atherosclerosis. 2017;262:51–54. doi:10.1016/j.  53.  Sundman MH, Chen NK, Subbian V, Chou YH. The bidirectional
             atherosclerosis.2017.05.007                        gut-brain-microbiota axis as a potential nexus between traumatic
          34.  Walker RE, Jackson KH, Tintle NL, et al. Predicting the effects   brain injury, inflammation, and disease.  Brain Behav Immun.
             of supplemental EPA and DHA on the omega-3 index. Am J Clin   2017;66:31–44. doi:10.1016/j.bbi.2017.05.009
             Nutr. 2019;110(4):1034–1040. doi:10.1093/ajcn/nqz161
          35.  Rittenhouse M, Sambuughin N, Deuster P. Optimization of   PMID: 38830308; DOI: 10.55460/V9MD-53OJ
             omega-3 index levels in athletes at the US Naval Academy: per-
             sonalized omega-3 fatty acid dosage and molecular genetic ap-
             proaches. Nutrients. 2022;14(14):2966. doi:10.3390/nu14142966



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