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Deployment of the Surgical                   Evaluation of Hemostatic Capacities
                Life-Saving Module (SLM) in 2017                    among Commando Candidates


                 Lessons Learned in Setting Up and                Would their Blood Suit a Hemorrhagic
                 Training Operational Surgical Units               War-Injured Patient in Case of Blood
                                                                        Donation on the Battlefield?

                          Brice Malgras, MD, PhD
                                                                         Yann D, MD ; Sébastien C, MD ;
                                                                                                       2
                                                                                     1
              Introduction                                           Rachel Foricher, MD ; Carine Hejl, MD ;
                                                                                         3
                                                                                                           4
                                                                                                              6
                                                                                       5
              The military operations carried out by the French armed forces   Stéphane Travers, MD ; Vincent Foissaud, MD ;
              occasionally require the use of the Surgical Lifesaving Module   Christophe Martinaud, MD, PhD 7
              (SLM) to ensure the surgical support of its soldiers. Because of
              its extreme mobility and capacity of fast deployment, SLM is
              particularly useful in small-scale military operations, such as   Background
              Special Forces missions. In 2017, the French SLM was for the   In case of a warm fresh whole-blood transfusion on the bat-
              first time used to ensure surgical support of allied forces that   tlefield, the blood donation usually occurs just after a com-
              were lacking forward surgical capabilities.        bat phase and often after several days on the field. To explore
                                                                 the hemostatic capacity of such blood, we analyzed the blood
              Methods                                            of volunteers attending the commando course of the French
                                                                 Navy, considering this course as an experimental model, plac-
              The SLM is a mobile, heliborne, airborne, surgical structure   ing them into the same physiological conditions as those faced
              with parachuting capability onto land or sea, and therefore   by deployed fighters.
              essentially focused on lifesaving procedures, also known as
              “damage control” surgery. Because of the need for mobility
              and rapid implementation, the SLM is limited to a maximum   Methods
              of five interventions or, in terms of injuries, to one or two seri-  Venous blood was collected at the beginning of the course,
              ously injured patients.                            mimicking the volunteers’ baseline status, and a second time
                                                                 6 weeks later, from the remaining candidates, during the actual
              Results                                            commando training, mimicking the stress conditions. For each
                                                                 candidate, we observed the differences between the two blood
              Over a period of 2 months, five medical teams were succes-  samples.
              sively deployed with the SLM. A total of 157 casualties were
              treated. The most common injuries were caused by shrapnel
              (56%), followed by firearms (36%), and blunt trauma (2.5%).   Results
              Injuries included the limbs (56%), thorax (18%), abdomen   Of the 112 men who attended the first day of the course, only
              (13%), head (11%), and neck (2%). The average Injury Se-  17 remained 6 weeks later. In the second blood samples, we
              verity Score (ISS) was 8.5 (range: 1 to 25), with 26 patients   noted significantly increased leucocyte and platelet counts
              presenting with an ISS≥15. The average New Injury Severity   and significantly decreased hematocrit and hemoglobin levels.
              Score (NISS) was 10.8 (range: 1 to 75), with 34 casualties hav-  Thrombin generation assays showed significantly lower nor-
              ing an NISS≥15. The surgical procedures were broken down as   malized peak heights (-31%), lower normalized endogenous
              follows: 126 dressings, 16 laparotomies, seven thoracotomies,   thrombin potential values (-29%), and lower velocity index
              12 isolated thoracic drains (without thoracotomy), one cervi-  (-35%). Normalized lag time and time to peak did not differ.
              cotomy, 12 amputations, seven limb splints, two limb fascioto-  Viscoelastometric testing revealed a significant increase in clot
              mies, two external fixators, and one femoral fracture traction.  firmness as assessed by maximum amplitude and amplitude at
                                                                 6 minutes. The clot speed was significantly increased.
              Conclusion
              The numerous SLM deployments in larger operations high-  Conclusion
              lighted its ability to adapt in terms of both equipment and   This work brings to light new data on coagulation during pro-
              personnel.  Continuous management  of equipment  logistics,   longed and considerable physical exercise. No obvious delete-
              robust personnel training, and appropriate organization of the   rious modification of hemostatic properties was observed. The
              evacuation procedures were the key elements for optimizing   decrease of the endogenous thrombin potentials may reflect a
              combat casualty care. As a consequence, the SLM appears to   better ability to control the thrombin generation once started.
              be an operational surgical unit of choice during deployments.  Altogether, these results suggest that this blood could well suit
                                                                 a hemorrhagic war-injured patient.
              Dr Brice Malgras is affiliated with the Bégin Military Teaching Hospi-
              tal, Saint-Mandé, France.                          1 Dr Yann D is affiliated with the Paris Fire Brigade, Emergency Med-
                                                                               2
                                                                 ical Service, France.  Dr Sébastien C is affiliated with the French Mil-
                                                                 itary Medical Service, 7ème  Antenne Médicale Spécialisée, France.
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