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that caffeine may increase blood flow and muscle tissue sat-  the condition on susceptibility to enemy fire was exceptionally
                                                                  2
          uration  that  may  increase  lower-body  muscle  function. 47–49    low (η = .001) and would have required many subjects (ap-
          We found no significant effect of caffeine on fire-and-move   proximately 200) to detect statistical significance. Lastly, tac-
          simulation performance (i.e., repeated sprints), corroborating   tical combat movements are conducted with multiple soldiers
          the results of others. 24,44,50–55  It is possible that providing sub-  and units. Thus, our findings may not translate when multiple
          jects with a substance that potentially had an active-ingredient   soldiers work together during direct-fire engagements. 8
                                  56
          elicited an ergogenic response.  However, this explanation is
          unlikely since nearly half of the subjects reported no perceived
          effect from the placebo supplement. Alternatively, it is possible   Conclusion
          that the familiarization session was unsuccessful in mitigating   Our investigation determined the effects of caffeinated gum on
          a learning effect.                                 marksmanship, cognition, bound duration, and susceptibility
                                                             to enemy fire during a tactical combat movement simulation.
          Stressful environments are reported to cause decrements to   The authors found that susceptibility to enemy fire increased,
          aspects of lower cognitive function and decision-making. 10–12    and that cognitive performance decreased during the tacti-
          The fire-and-move simulation deteriorated cognitive perfor-  cal combat movement simulation. However, caffeine did not
          mance, but not marksmanship. This is perhaps because it did   change marksmanship, cognition, bound duration, or suscep-
          not  provide enough stress  to deteriorate  marksmanship. 57,58    tibility to enemy fire. Significant increases in bound duration
          Stress-induced cognitive decline, such as sleep deprivation, is   indicates that susceptibility to enemy fire increased during the
                                                         22
          often mitigated  with caffeine supplementation  in soldiers.    repeated bounds, which, in turn, may decrease soldier surviv-
          Caffeine also improves complex soldier tasks such as marks-  ability. While caffeine was not effective at maintaining bound
          manship reaction  time. However, the effects  of caffeine  on   duration or changing marksmanship or cognitive performance,
          marksmanship accuracy are not well documented. 59  the authors cannot discount the possibility of improvements in
                                                             performance from caffeine after sleep deprivation.
          Our analysis revealed that neither cognitive performance,
          marksmanship reaction time,  nor  marksmanship  accuracy   Acknowledgments
          were different between placebo and caffeine conditions. Our   The authors would like to thank Shea Crum, Blake Goodman,
          results  confirm  previous  reports  documenting  no  improve-  and Jason Sartor for their efforts in assisting with data collec-
          ments in marksmanship accuracy after caffeine supplementa-  tion, as well as Rikki Stein for helping curate Figure 1.
          tion when protocols elicit a stressful environment without sleep
          deprivation. 28,60–63  Additionally, this is the first study to docu-  Funding
          ment the effects of caffeine supplementation on marksmanship   The work was supported by Kansas State University College
          reaction time during a fire-and-move simulation without sleep   of Health and Human Sciences Doctoral Dissertation Award
          deprivation. Our findings suggest that caffeine supplemen-  and the Kansas State University Arts, Humanities, and Social
          tation does not improve marksmanship reaction time. Thus,   Sciences Small Grant.
          caffeine’s ergogenicity on marksmanship parameters may only
          be revealed in sleep-deprived subjects. 29,64,65  Collectively, our   Disclosure
          findings suggest that caffeine was not an effective ergogenic aid   The authors have indicated they have no financial relation-
          during a simulated tactical combat movement in rested sub-  ships relevant to this article to disclose.
          jects. However, understanding the effects of caffeine on per-
          formance during direct-fire engagements while sleep-deprived   Author Contributions
          may have implications to soldier survivability during sustained   JAS, JAD, TCH, and K. M. Heinrich conceived the study con-
          operations and presents an avenue for future investigations.  cept. JAS and TCH obtained funding. JAS recruited partici-
                                                             pants and coordinated and collected data, JAS, JAD, CMB,
          The current investigation was strengthened by a robust study   CDB, K. M. Holte, and BKK acquired data. JAS analyzed data
          design with subjects serving as their own controls in a dou-  and wrote the first draft of the manuscript. All authors read
          ble-blind, counterbalanced, crossover design that determined   and approved the final manuscript.
          the effects of caffeinated gum. This study also utilized a com-
          bat-relevant protocol that induced both physical and cogni-  References
                                                             1.  USA Department of Defense.  Defense causality analysis system.
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          this influenced our out comes or interpretations.  Our study   4.  Hunt AP, Tofari PJ, Billing DC, et al. Tactical combat movements:
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