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Step Duration Effects on Blood Loss in
                            Simulated Designs of Tourniquet Use Procedure




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                       John F. Kragh Jr, MD *; James K. Aden 3rd, PhD ; Michael A. Dubick, PhD 3







          ABSTRACT

          Background: We sought new knowledge by further developing   remain somewhat unclear, partly because most data on emer-
          a model of using calculations in the simulation of a first-aid   gency use are limited  and of low certainty. 9
                                                                             6–8
          task. The purpose of this study was to develop the model to
          investigate the performance of tourniquet use in its component   Tourniquet use comprises component steps ordered routinely
          steps. Methods: We aimed to design an experiment on a desk-  by design. Step performance in simulation and clinical care
          top computer by mathematically manipulating simulated data   can be assessed using metrics. A common metric is the dura-
          in tourniquet use. A time factor of tourniquet use was ranged   tion between injury and bleeding control. A long time risks
          widely through time challenges in five degrees from ideal to   shock and death. An understanding of when a step is per-
          worst performances. Redesigning the task was assessed by   formed unsatisfactorily can inform where future developments
          time costs and blood losses. Results: The step of tourniquet   might improve care.
          application took 17% of the trial time and securing the tour-
          niquet after bleeding control took the longest amount of the   In 2018, we made calculations to inform our understanding
          trial time, 31%. A minority of the time (48% [17% + 31%]   of tourniquet use by including the step of donning medical
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          to apply tourniquet plus secure it) was spent after the tour-  gloves.  Extra blood volume lost in simulation while donning
          niquet touched the patient, whereas most of the time (52%)   gloves was, on average, 239mL. Before steady bleeding was
          was spent before the tourniquet touched the patient. The step   stopped, a relationship among the steps became clear: step
          of tourniquet application lost 14% of the total blood lost,   times  and  blood  loss  were  causally  linked.  However,  after
          whereas no blood was lost during securing the tourniquet,   bleeding control, times and losses were unassociated. Donning
          because that was the moment of bleeding control despite se-  gloves controlled the risk of infection, but uncontrolled bleed-
          curing the tourniquet taking much time (31%). Most (86%)   ing was prolonged by the donning time. In the task’s design,
          of blood lost occurred before the tourniquet touched the pa-  the risk of infection was prevented but inadvertently at a cost
          tient. But blood losses differed 10-fold, with a maximum of   of blood loss. The design produced a profile of risks that re-
          2,434mL, which, when added to a pretask indication blood   vealed itself: donning gloves harmed the patient by delaying
          loss of 177mL, summed to 2,611mL. Before redesigning the   control of bleeding, yet infection control benefited both the
          task, costs of donning gloves and calling 9-1-1 included un-  caregiver and the patient. A tradeoff of risks and benefits was
          controlled bleeding, but gloving mitigated risk of spreading   seen between the steps and the persons.
          pathogens among people. By step and person, redesigns of the
          task altered the risk-benefit profile. Conclusions: The model   Given that unexpected tradeoff, we sought new knowledge
          was useful because it simulated where most of the bleeding   of other possible tradeoffs by broadening our way of using
          occurred before the tourniquet touched the patient. Model-  calculations in simulation. The purpose of this study was to
          ing simulated redesigns of the task, which showed changes in   develop the previous mathematical model to investigate the
          the task’s risk-benefit profile by step and among persons. The   performance of tourniquet use in its component steps. The fo-
          model generated hypotheses for future research, including the   cus was on duration effects on bleeding.
          capability to screen candidate ideas among task designs.
                                                             Methods
          Keywords: tourniquet; first aid, bleeding control and preven-
          tion; emergency; task deconstruction, simulation, modeling  This study was conducted in December 2019 within the lim-
                                                             its of protocol guidelines at the US Army Institute of Surgical
                                                             Research. The design was an experiment of simulated data on
                                                             a desktop computer of tourniquet use by mathematical ma-
          Introduction
                                                             nipulations. The study was designed to model a time factor
                                                    1,2
          Anyone may have to give first aid in care for an injury.  First-  of tourniquet use through a wide spectrum of simulated per-
          aid experts recommend tourniquets to help control bleeding   formances. The spectrum was made large to simulate many
                         3–5
          from limb wounds.  However, tourniquet indications and use   emergency caregiving episodes with different degrees of time
          *Correspondence to 3698 Chambers Pass, Joint Base San Antonio Fort Sam Houston, TX; or john.f.kragh.civ@mail.mil
          1 Dr Kragh is a researcher of bleeding control at the Institute of Surgical Research (ISR), Fort Sam Houston, TX, and an associate professor in
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          the Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD.  Dr Aden is a statistician at the Brooke Army
          Medical Center, Fort Sam Houston, TX.  Dr Dubick is a researcher and chairperson of the Department of Hemorrhage Control and Resuscitation
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          at the ISR.
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