Page 116 - JSOM Fall 2018
P. 116

o Similar to adults, early transfusion therapy should be   clinical condition of all the patients requiring the attention of
               started sooner rather than later. LTOWB and FWB are   the provider making the decision. It will not always be possi­
               both acceptable to give to children with life­threatening   ble to save all team members.
               hemorrhage. There is no contraindication to the use of
               any WB product in children. The initial dose for blood   A determination that further attempts to save a life are futile
               is 10mL/kg, but in children with massive hemorrhage,   does not necessarily mean cessation of clinical care for the
               blood products can be given in higher doses as fast as   patient. All reasonable interventions to reduce pain and suf­
               needed to gain hemodynamic stability. Massive transfu­  fering, short of hastening death (e.g., not giving a lethal dose
               sion in pediatrics has been defined as more than 40mL/  of opiates) should be provided. At times, agonal respirations
               kg of blood products in 24 hours. WB is easier to titrate   and bodily movement can take place in the dying process; be
               effectively in children than component therapy.  prepared for this in the sight of comrades and be prepared
               o Children are at high risk of developing hypocalcemia,   to explain this. This is not a reason to continue resuscitative
               hypomagnesaemia, metabolic acidosis, hypoglycemia,   efforts.
               hypothermia, and hyperkalemia during transfusion.
               Therefore, frequent monitoring (every hour if possible)   If a casualty dies, all medical interventions should be left in
               and correction of acid/base status, electrolytes, and core   place if feasible. If supplies may be needed for future casual­
               temperature is indicated during the resuscitation of pe­  ties and resources are critically limited, it may be necessary to
               diatric casualties, when available.           reuse medical devices (e.g., cricothyrotomy kits, chest tubes).
                                                             After death, a casualty should not be used as a blood donor for
          End-of-Life/Expectant Management                   surviving casualties. Every attempt should be made to find al­
                                                             ternate donors for any surviving casualties. Transfusing blood
          Determining futility of care: despite best efforts, certain injuries
          are not survivable in austere environments. The tactical situ­  from a deceased  casualty may result in transfusing  acidotic
          ation, casualty clinical condition, and operational constraints   and hypocoagulable blood, thus worsening the surviving casu­
          (e.g., mass casualty incidents, logistics) may warrant the con­  alty’s hemostatic physiology and possibly causing death.
          sideration of ceasing ongoing, aggressive resuscitative efforts.
                                                             Providers facing the dilemmas around patient death and ces­
          The provider must use all their operational knowledge to de­  sation of resuscitative efforts should also be cognizant of the
          termine the utility of ongoing resuscitation. As a guide only,   effects on team members, other patients, and on themselves.
          examples of wounds with low chance of survival include:  Various strategies for coping with these challenges may be ap­
               o Cranial injuries with exposed brain matter (exception   propriate in different circumstances. A full exploration of the
               may be isolated frontal lobe injuries) or severe TBI with   topic is beyond the scope of this CPG; however, some consid­
               signs of herniation (i.e., dilated pupils, hypertension   eration of these issues should be built into individual and unit
               plus bradycardia) or Glasgow Coma Scale score 3–5  training for PFC scenarios.
               o Penetrating thoracic or abdominal injuries that:
               ■ ■ Are hypotensive or nonresponsive after two units   Appendix C. Whole Blood Draw and Storage Planning Guide.
                 blood transfusion, bilateral chest decompression (nee­  Appendix  D.  Damage  Control  Resuscitation  in  Prolonged
                 dle decompression/finger thoracostomy/tube thoracos­  Field Care Summary Table.
                 tomy), and assessment for pericardial tamponade.
               o Junctional amputations with pelvic disruption  Author Contributions
               o Out­of­hospital cardiac arrest (despite bilateral chest   All authors approved the final version of the manuscript.
               decompression),  especially  if  surgical  resuscitation  is
               more than 10 minutes away                     References
                    – Blunt trauma mechanism without organized ac­  1.  Gurney JM, Spinella PC. Blood transfusion management in the se­
                    tivity on cardiac monitor                  verely bleeding military patient. Curr Opin Anesthesiol. 2018;31:
                    – Cardiopulmonary resuscitation for longer than 5   207–214.
                    minutes                                  2.  Spinella PC, Perkins JG, Grathwohl KW, et al. Risks associated
                    – No cardiac motion observed on FAST examina­  with fresh whole blood and red blood cell transfusions in a combat
                    tion or palpated with left finger thoracostomy  support hospital. Crit Care Med. 2007;35:2576–2581.
                    – Cardiac monitoring reveals:            3.  Spinella PC, Perkins JG, Grathwohl KW, et al. Warm fresh whole
                                                               blood is independently associated with improved survival for pa­
                    f   Asystole                               tients with combat­related traumatic injuries. J Trauma. 2009;66:
                    f   No organized rhythm                    S69–S76.
                    f   Wide complex/idioventricular rhythm  4.  Nessen SC, Eastridge BJ, Cronk D, et al. Fresh whole blood use by
               o Cervical spine trauma with cardiovascular collapse  forward surgical teams in Afghanistan is associated with improved
               o Obvious massive trauma, such as total body disruption   survival compared to component therapy without platelets. Trans-
                                                               fusion. 2013;53:107S–113S.
               and decapitation                              5.  Holcomb JB, Jenkins D, Rhee P, et al. Damage control resusci­
               o Nonresponders                                 tation: directly addressing the early coagulopathy of trauma.  J
                                                               Trauma. 2007;62:307–310.
          Before cessation of resuscitation attempts by the provider, ev­  6.  Eastridge BJ, Mabry RL, Seguin P, et al. Death on the battlefield
          ery attempt should be made to contact medical direction for   (2001­2011): implications for the future of combat casualty care. J
          input. If contact with higher medical direction is not feasible,   Trauma Acute Care Surg. 2012;73:S431–437.
          then the on­scene provider must use their best judgment for   7.  Malsby RF, Quesada J, Powel-Dunford, et al. Prehospital blood
                                                               product transfusion by U.S. army MEDEVAC during combat oper­
          ongoing resuscitation  attempts.  This may  include an  assess­  ations in Afghanistan: a process improvement initiative. Mil Med.
          ment of available resources, timing of evacuation, and the   2013;178:785–791.


          114  |  JSOM   Volume 18, Edition 3 / Fall 2018
   111   112   113   114   115   116   117   118   119   120   121