Page 53 - Journal of Special Operations Medicine - Summer 2016
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the appliance and the instrument.  Rohrer and Bulard   weight of a typical autoclave. Their disadvantage is that
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              were able to overcome this problem by insulating their   they must be properly mixed in the correct concentra-
              metal instruments with a radar absorbent material. Al-  tion, and most have a limited storage and use time.
              though radar absorbent material is likely to be difficult
              to obtain, a cursory search of the Internet showed that   The two most common forms of chemical disinfection
              microwave absorbable material could be obtained in   are 2% glutaraldehyde and 6% hydrogen peroxide.
              bulk 9-inch sheets for around US$180. In light of this   Either agent can achieve high level disinfection after
              evidence, commercial microwave ovens present a novel   30 minutes of immersion in a chemical bath with the
              and field expedient alternative to traditional sterilization   proper concentrations as mentioned earlier.
              methods; however, this has not been approved by the
              US Food and Drug Administration, and further study   1. Glutaraldehyde  is commercially available in a 2%
              is needed to establish a protocol for metal instruments.  aqueous solution, but it comes in a kit that requires the
                                                                 addition of a buffer in powder or liquid form to become
                                                                 activated. Immersion for 30 minutes is enough to pro-
              Disinfection
                                                                 vide high-level disinfection, but it can also provide ster-
              Recall that by definition, there are two types of disinfec-  ilization if left for a total soak time of 10 hours. Ideally
              tants: high level and low level. High-level disinfection   after immersion instruments should be rinsed with ster-
              kills all microorganisms except spores; low-level disin-  ile water to remove any excess solution.
              fection can kill most bacteria, some viruses, and some
              fungi, but also has no effect on spores.           Glutaraldehyde is a lucrative option since it can provide
                                                                 both high-level disinfection and sterilization, but it does
              High-Level Disinfection by Boiling                 have some significant drawbacks. First, once activated,
              Sterilization is the preferred method for any cutting,   the solution should not be kept for more than 2 weeks.
              piercing, or invasive instrument. But if sterilization is not   Second, it tends to be expensive. And third, the solution
              available or not practical, then high-level disinfection by   gives off a toxic vapor that prevents it from being used
              boiling is a reasonable alternative.  This is achieved by   in enclosed spaces, and skin contact should be avoided.
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              placing instruments in boiling water for a minimum of
              20 minutes, and it is an effective and reliable method   2. Hydrogen peroxide  exerts its disinfectant potential
              for inactivating microbes, including HIV and hepatitis B   though its oxidizing ability. This agent is often readily
              virus. At 1 atmosphere (1 ATM) of pressure (sea level),   available over-the-counter; however, a 6% concentra-
              water boils a constant temperature of 100°C (212°F).   tion is required for disinfection. In the United States,
              However, as you increase in altitude, you thereby de-  hydrogen peroxide can be found in just about any drug
              crease the atmospheric pressure, and water will boil at   store, but the concentration is rarely found above 3%.
              a lower temperature. We could not find any data that   The common form stocked in the standard MES set is
              suggest that this does or does not affect the reliability of   3% as well. To ensure the 6% recommended solution,
              boiling disinfection. Given the current high-altitude op-  it can be purchased in a concentrated 30% form, and
              erations in Afghanistan, the affects of altitude on boiling   mixed with a combination of 1 part hydrogen peroxide
              point depression should be taken into consideration if   to 4 parts boiled water. Once again, the recommended
              choosing to rely on boiling disinfection.          soak time is 30 minutes. Due to its strong oxidizing abil-
                                                                 ity, it should not be used on copper, aluminum, zinc, or
              High-Level Chemical Disinfection                   brass.
              If sterilization is not available and boiling disinfection
              is  not available,  then  high-level  chemical  disinfection   In addition to the WHO’s recommendations of Glutar-
              can be considered for instruments as a method of last   aldehyde and Hydrogen peroxide, the United Nations
              resort. It should be noted, however, that it is not recom-  High Commissioner for Refugees also recommends the
              mended  for hollow needles  or syringes.  This  method   use to the following alternative agents :
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              should only be used if the concentration of the chemi-
              cal bath can be ensured, and all instruments must be   3. Chloramine: Usually found in powder or tablet form,
              thoroughly cleaned of gross organic material prior to   chloramine can be used for water purification, as a sur-
              emersion in the chemical bath. A thorough cleaning is   face wound antiseptic, and as a disinfectant for surgical
              required to ensure adequate chemical penetration, and   instruments and medical surfaces. It can also be found
              instruments should be towel dried of excess water be-  commercially in the form of aquarium cleaner or wa-
              fore emersion to prevent unintentional dilution of the   ter purification tablets. It is typically found in 250mg,
              chemical bath. Chemical disinfection has a weight ad-  500mg, or 1g tablets. As other dis infectants, it must
              vantage over steam sterilization, in that 1L of liquid dis-  first be made into a solution, preferably  with  boiled
              infectant weights approximately 2.2lb, versus the 43lb   water, and only in the recommended concentrations.



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