Page 139 - Journal of Special Operations Medicine - Spring 2015
P. 139

Figure 2  Sand fly life cycle.                     Before initiating treatment, it is prudent to consult with
                                                                 the leishmaniasis experts at the CDC or with an infec­
                                                                 tious disease physician experienced in the care of pa­
                                                                 tients with this disease.


                                                                 Importance in a Deployed Setting
                                                                 Several hundred military patients with cutaneous leish­
                                                                 maniasis were treated at US military treatment facilities
                                                                 early in the conflicts in Afghanistan and Iraq, when US
                                                                 Servicemembers were bedding down in areas where the
                                                                 sand flies were in great numbers. The insect vector is
                                                                 challenging, as it is actually too small to be controlled
                                                                 by standard bed netting. Personal protection by using
                                                                 permethrin­treated bed nets and uniforms, as well as
                                                                 judicious use of  N,N­diethyl­meta­toluamide (DEET)­
              Source: http://www.cdc.gov/dpdx/leishmaniasis/.    containing insect repellent on exposed skin, is key to
                                                                 prevention. Personnel should also locate areas where the
              Diagnosis                                          sand flies live and breed and spray them with insecti­
              The US Centers  for Disease Control  and Prevention   cides to control their population.
              (CDC) provides reference diagnostic services for leish­
              maniasis. For cutaneous leishmaniasis, the diagnosis is   Disclaimer
              made by finding the parasite or its DNA in skin tissue.
              Methods of collection and submission of tissue for diag­  The views expressed in this publication are those of the
              nosis can be found at the following website: http://www.  author and do not reflect the official policy or position
              cdc.gov/parasites/leishmaniasis/health_professionals/  of the Department of the Army, Department of Defense,
              index.html#dx, or by contacting the CDC directly at   or the US Government.
              +1 404­718­4175. A new rapid assay, the CL Detect
                                                            ™
              Rapid Test (InBios International, Inc), was recently ap­  Disclosure
              proved by the US Food and Drug Administration. More
              information on this test, developed in part by Army re­  The author has nothing to disclose.
              searchers, can be found at  inbios.com.
                                                                 Bibliography
              Treatment                                          US Centers for Disease Control and Prevention. Infectious diseases
                                                                    related to travel. In: CDC Health Information for Interna­
              Treatment of cutaneous leishmaniasis infections is com­  tional Travel. http://wwwnc.cdc.gov/travel/yellowbook/2014/
              plicated in that more than 20 different types of the para­  chapter­3­infectious­diseases­related­to­travel/leishmaniasis
              site exist worldwide, and different types cause different   ­cutaneous.
              manifestations of the disease, which respond differently   US Centers for Disease Control and Prevention. Parasites: leish­
              to the treatments available. Drug treatments used in the   maniasis. http://www.cdc.gov/parasites/leishmaniasis/.
              recent past include Pentostam  (sodium stibogluconate;
                                       ®
              GlaxoSmithKline plc; hcp.gsk.co.uk/products/pentostam
                             ®
              .html), AmBisome  (liposomal amphotericin B;  Astellas   COL Burnett is currently the Area­Support Group­Kuwait
              Pharma  US,  Inc;  www.ambisome.com),  and  the  oral   Command Surgeon and is board­certified in pediatrics and pe­
              agent miltefosine. Local therapies of cryotherapy with   diatric infectious diseases. He has served overseas in  Korea,
              liquid nitrogen, and thermotherapy, with the use of a   Germany, Kosovo, Iraq, Afghanistan, Kuwait and as the
              localized current of radiofrequency heat, have been tried   JSOTF­P Surgeon in the Philippines. He is a graduate of the
              with some success. No vaccination is available for pre­  University of Wisconsin­Madison and the Medical College of
              vention of leishmaniasis infections.               Wisconsin.













              Cutaneous Leishmaniasis                                                                        129
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