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reported side effect is argyria, an aesthetic defect, which   Pseudomonas aeruginosa, and Enterobacter  sp. (the
          is characterized by gray to gray-black staining of the skin   “ESKAPE bugs”). 15,16  Silverlon demonstrates a bacteri-
          and mucous membranes produced by silver deposition.   cidal power against all of these multidrug-resistant bac-
                                                             teria. To date, no bacteria that resist silver ions have
          In general, silver ions have multiple activities. Their   been documented, and there are no clinical studies that
          important biological properties and actions on burn   confirm any type of resistance for the most dangerous
          wounds can be summarized by the high bactericidal and   bacteria. 17,18
          fungicidal activity of the ions, stimulation of epidermal
          regeneration, local zinc and hydrogen sulfide reduction,   For all wounded patients in war zones, the risk of an
          anti-itching activity, and reduction of metalloproteinase   overt infection with these multidrug-resistant bugs is
          activities. All of these are important causes of delaying   very high. Moreover, Soldiers who have been burned by
          healing time in wounds.                            any type of explosion are at greater risk of infection.
                                                                                                            19
                                                             It is necessity to act fast to clean and dress the burned
          Silverlon  Burn Dressings are elastic bandage made with   area. Silver-nylon burn wrap dressing is both resistant
                  ®
          nylon and plated with pure metallic silver. The product   and elastic, essential properties for a dressing to be eas-
          was approved by the U.S. Food and Drug Administra-  ily used in either the operating room or on the battle-
          tion in 2003 for the following uses: first- and second-  field. 20,21  Furthermore, its ease of use and its versatility
          degree burns, donor and graft sites, surgical wound and/  allow the use of this dressing by fellow Soldiers. This
          or incision, dehiscent surgical wound, pressure ulcers,   has a double action in a very short time: the bactericidal
          diabetic foot lesions, and venous ulcers (the use in the   effects of silver ions and protection and isolation of the
                                            9
          two cases for third-degree burns was off label). Silver-  wound from the external environment. The practicality
          nylon burn wrap dressing has a wide bactericidal spec-  of having a silver-nylon dressing roll facilitates the treat-
          trum and can be left on the wound for up to 7 days.    ment and dressing of a large, wounded surface quickly,
                                                         10
          It builds a barrier against attack from new bacteria,   fulfilling the medical and tactical needs.  This use-
                                                                                                  22
          it is slightly absorbent, and it allows a path for exces-  ful dressing is widely disseminated by the U.S. Armed
          sive wound exudates. It does not adhere or stick to the   Forces and would be practical as part of the medical
          wound, so it can be kept in direct contact with wound   armamentarium of other European military forces en-
          bed. In its roll and elastic configuration, it allows the   gaged in various international missions under the North
          user  to  address  even  difficult  anatomic  sites  or  entire   Atlantic Treaty Organization flag.
          limbs. It is imperative to moisten the dressing before po-
          sitioning it onto the wound so the silver ions can rapidly
          start and maintain their action. The amount of pure me-  Conclusion
          tallic silver held in Silverlon dressings is approximately    The ease of use of the Silverlon Burn Dressing and the
          5799µg/cm , which is the most concentrated dressing   Silverlon Burn Glove, as well as their effectiveness in
                    2
          available compared with other silver-based dressings or   eliminating infection and preserving the patient’s wound
          creams. The amount of silver ions released by Silverlon   from external insults during the first emergency care,
          shows a rapid onset by killing bacteria present in the   was shown it to be essential in treating badly burned
          wound within a very short time.                    Soldiers on the battle range. It would be desirable to
                                                             have a larger dissemination and use by medical and
          Since 2003, Silverlon has been widely used by the U.S.   paramedical personnel engaged in the war zone.
          Army, especially in war theatres like Iraq and Afghani-
          stan.  It is a light, noncumbersome dressing that is easy   Disclosures/Funding
              11
          to stock and transport. It has no particular storage needs
          since it can be kept in any environmental temperature   The authors state that there are no conflicts of interest
          without compromising its properties. It has been consid-  or funding.
          ered by the U.S. Department of Defense to be the “Stan-
          dard of Care” for the use on burn victims transported   References
          from one theater to another because the dressing can re-
          main for 7 days.  This avoids time-consuming dressing   1.  Lunardi F, Pozza M. ATLS versus TCCC: the Italian expe-
                        12
          changes for the medical staff and decreases pain and risk   rience on the battlefield [abstract]. Eur J Trauma Emerg
                                                               Surg. 2013;39(Suppl 1):S1–S162.
          of infection for the patient. 13,14  During the past decade,   2.  Chung KK, Wolf SE, Cancio LC, et al. Resuscitation of se-
          there has been a widespread outbreak, especially in   verely burned military casualties: fluid begets more fluid. J
          wounded military patients, of infections resistant to all   Trauma. 2009;67:231–237; discussion 237.
          known antibiotics. The multidrug-resistant bacteria of   3.  Chung KK, Blackbourne LH, Wolf SE, et al. Evolution of
          greatest concern are Enterococcum faecium, Staphylo-  burn resuscitation in Operation Iraqi Freedom. J Burn Care
          coccus aureus, Klebsiella sp., Acinetobacter baumannii,    Res. 2006;27:606–611.



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