Page 24 - JSOM Spring 2026
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Combat-Related Orthopedic Trauma in the Russo-Ukrainian War

                                               A Systematic Review



                           Rafael Garcia-Cañas, MD, PhD *; Ricardo Navarro-Suay, MD, PhD   2
                                                         1








          ABSTRACT
          Introduction:  The Russo-Ukrainian conflict has produced   approximately 382,000 military casualties in 2025 and more
          large numbers of military and civilian casualties, with ortho-  than 1,168,000 cumulative  casualties since  the beginning of
          pedic and musculoskeletal trauma representing a major pro-  the full-scale invasion.   Although precise Ukrainian military
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          portion of  combat  injuries.  Explosions, gunshots,  and  blast   casualty figures are not publicly disclosed for security reasons,
          mechanisms frequently generate complex wounds that demand   international security analyses note that Ukraine continues to
          specialized surgical and rehabilitative management.  This re-  experience significant losses consistent with the intensity and
          view summarizes injury types, mechanisms, severity, clinical   duration of large-scale conventional warfare.  Civilian casu-
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          responses, and gaps in current knowledge. Methods: Following   alties documented by the United Nations exceed 30,000 con-
          PRISMA guidelines, a comprehensive search of PubMed, Sco-  firmed deaths and injuries, with actual numbers likely higher
          pus, Web of Science, and MEDLINE via WoS was conducted   due to incomplete reporting from frontline and occupied areas.
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          in February 2025. Eligible studies published from 2014 to   Humanitarian assessments further indicate that more than 14
          2024 included case reports, case series, cohort studies, and ob-  million people have been displaced internally or abroad since
          servational research describing orthopedic injuries in military   2022, illustrating the extensive societal impact of the conflict
          or civilian populations affected by the conflict. Two reviewers   beyond direct battlefield casualties.  Among the recorded inju-
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          independently screened studies, performed quality assessments   ries, orthopedic and musculoskeletal trauma constitute a major
          using Joanna Briggs Institute tools and STROBE criteria, and   proportion, consistent with long-standing evidence demon-
          synthesized data qualitatively with descriptive statistics when   strating that extremity trauma represents the leading source of
          available. Results: Thirty-one studies were included, primarily   long-term disability in modern armed conflicts. 5
          case reports and retrospective analyses from Ukrainian military
          hospitals and frontline facilities. Explosive and ballistic trauma   Modern warfare is characterized by the extensive use of ex-
          produced high-energy fractures, traumatic amputations, severe   plosives, ballistic trauma, and high-energy transfer injuries,
          soft-tissue loss, and neurovascular damage. Management strat-  leading to  increasingly complex  musculoskeletal  conditions
          egies included external and internal fixation, bone grafting,   that necessitate specialized medical expertise. Amputation re-
          microsurgical reconstruction, distraction osteogenesis, and the   mains one of the most prevalent consequences of severe mine-
          progressive use of 3D-printed implants to support limb salvage.   explosive injuries, which are often marked by extensive tissue
          Rehabilitation, including pain control, physiotherapy, and pros-  destruction and crushing.  To optimize limb function follow-
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          thetic training, was essential for functional recovery. Long-term   ing such severe injuries, reconstructive and restorative surgical
          complications included neuromas, phantom pain, stump mor-  procedures are critical.  While contemporary surgical tech-
          bidity, and psychological trauma. Telemedicine enabled remote   niques prioritize limb preservation, complications such as ex-
          consultation and continuity of care under resource-limited   tensive scarring, bone spurs, and soft-tissue abnormalities pose
          conditions. Conclusions:  Combat-related orthopedic injuries   challenges to prosthetic fitting and functional rehabilitation. 7,8
          in this conflict require advanced surgical techniques, coordi-
          nated multidisciplinary support, and prolonged rehabilitation.   Military conflicts have profound implications for orthopedic
          Expanded data collection, standardized reporting, and long-  surgery, as evidenced by the significant rise in cases requir-
          term follow-up are essential to improve functional outcomes   ing limb salvage procedures, complex fracture management,
          and reintegration.                                 and prolonged rehabilitation. 5,6,9,10  The management of war-
                                                             related orthopedic injuries in Ukraine places a considerable
          Keywords: war-related injuries; Ukraine conflict; military   strain on the healthcare system, necessitating the involvement
          medicine; casualty; surgical management; combat trauma  of both military and civilian medical institutions at tertiary
                                                             and quaternary levels.  Consequently, there is a pressing need
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                                                             for innovative surgical techniques and enhanced rehabilitation
                                                             strategies to optimize patient outcomes. 11
          Introduction
          The Russo-Ukrainian conflict, ongoing since February 24,   Orthopedic departments play a crucial role in providing both
          2022, has resulted in substantial military and civilian casual-  scheduled and emergency care for patients with musculoskeletal
          ties. According to the UK Ministry of Defence, Russia sustained   trauma.  These departments function within multi disciplinary
          *Correspondence to garciacanas@icloud.com
          1 MAJ Rafael Garcia-Cañas is affiliated with the Orthopedic Unit and  LT COL Ricardo Navarro-Suay is affiliated with the Anesthesia Unit,
                                                            2
          Hospital Central de la Defensa Gómez Ulla, Madrid, Spain.
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