Page 168 - 2022 Ranger Medic Handbook
P. 168

ERYTHROMYCIN OPHTHALMIC OINTMENT
         Class: Macrolide antibiotic
         Dose: One-half inch ribbon of ointment q3–4hr or 2–6 × daily.
         Indications: For superficial ocular infections of the cornea and conjunctiva
         Contraindications: Hypersensitivity, astemizole, cisapride, pimozide, terfenadine therapy, pregnancy category may use
         during pregnancy and while breastfeeding
         Adverse/Side-effects: Minor ocular irritations and redness
         Interactions: Terfenadine, atorvastatin, lovastatin, pravastatin, simvastatin, carbamazepine, digoxin, diltiazem, midaz-
         o lam, oral contraceptives, ototoxic drugs, penicillins, warfarin
         Mission Impact: Blurred vision

         ESZOPICLONE (LUNESTA) – CONTROLLED SUBSTANCE IV
    SECTION 4  Class: Sedative-hypnotic
         Action: May potentiate effects of inhibitory neurotransmitter γ-aminobutyric acid (GABA) by binding close to or with
         benzodiazepine receptors
         Dose: 2mg up to 3mg immediately at bedtime. Maintenance dose 3mg
         Indications: Insomnia
         Contraindications: Hypersensitivity, pregnancy category consider alternative during pregnancy and avoid use while
         breastfeeding
         Adverse/Side-effects: Agitation, anxiety, confusion, depression, dizziness, hallucinations, HA, nervousness, neural-
         gia, unusual dreams, chest pain, peripheral edema, dry mouth, gynecomastia, diarrhea, indigestion, hepatitis, nausea,
         vomiting, decreased libido, dysmenorrhea, UTI, asthma, respiratory tract infection, pruritus, rash, or heat stroke
         Interactions: Clarithromycin, ketoconazole, itraconazole, rifampin, and alcohol
         Mission Impact: Grogginess. Puts patient at higher risk for heat injury. GROUNDING medication for per-
         sonnel on flight status

         FENTANYL – CONTROLLED SUBSTANCE II
         Class: CNS agent – potent narcotic (opiate) agonist
         Action: Action similar to that of morphine with more rapid and less prolonged analgesia and sedation, but less emetic
         effect
         Dose: 800mcg/dose (max 1600mcg/day); lozenge on a stick to be placed in mouth between cheek and lower gum and
         sucked, not chewed (have opioid antagonist [naloxone] immediately available!) IV: For severe pain 50–100mcg IV/IO/IM
         (consider doubling IV/IO dose for IM) q1–2hr prn
         Onset/Peak/Duration: TD: Onset 15 minutes; peak 20–40 minutes; duration 2–3 hours. IV/IO: Onset immediate; peak
         30–60 minutes; duration 2–4 hours
         Indications: For moderate to severe pain management
         Contraindications: MAOIs; myasthenia gravis; pregnancy category consider alternative during pregnancy and may
         use while breastfeeding (caution advised in patients trying to conceive)
         Adverse/Side-effects: Sedation, euphoria, dizziness, diaphoresis, delirium, convulsions, bradycardia, hypotension,
         circulatory depression, cardiac arrest; miosis, blurred vision; nausea, vomiting, constipation, ileus; muscle and tho-
         racic muscle rigidity; urinary retention, rash; laryngospasm, bronchoconstriction, respiratory depression or arrest
         Interactions: Alcohol and other CNS depressants potentiate effects; MAOIs may precipitate hypertensive crisis
         Mission Impact: GROUNDING medication for personnel on flight status

        154      SECTION 4   RANGER MEDIC PHARMACOLOGY & FORMULARY
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