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the requirements of continued education and training, and   research should evaluate the differences in performing autol-
          necessitates the requirement for effective administrative over-  ogous EFWBT versus simulated arm/IV trainers to determine
          sight to prevent undesirable patient outcomes.     whether autologous blood transfusions replicate real-world
                                                             applications.  This is paramount in ensuring the validity of
          Through international collaboration, the U.S. Military and   this research in assessing participants’ performance of DCR
          UHPs can enhance EFWBT awareness and training, reduc-  for hemodynamically unstable patients in simulated combat
          ing mortality rates for patients in austere operating environ-  conditions and the assessment of whether IV trainers create
               24
          ments.  Implementing a Ukrainian EFWBT program on a   disparities in confidence or competence in EFWBT training.
          larger scale requires careful planning, coordination, and adher-
          ence to regulatory guidelines to improve emergency medical   Conclusion
          response, enhance patient survivability, and reduce mortality
          rates in conflict zones. By clearly outlining objectives, the pro-  Our results demonstrated that the application of a Ukrainian
          gram can set a clear direction for the implementation efforts of   EFWBT training program can significantly increase UHPs’
          medical professionals, military leaders, logistical experts, and   confidence in conducting EFWBTs. Further larger-scale re-
          regulatory representatives to ensure effective oversight and co-  search is required to determine the impact of this training on
          ordination. This multidisciplinary approach ensures that the   concurrent performance outcomes. EFWBT has the potential
          EFWBT program benefits from the expertise and perspectives   to be a critical lifesaving capability in near-peer threat environ-
          of various stakeholders by enabling a comprehensive and inte-  ments and resource-restricted settings. However, its successful
          grated implementation strategy.                    implementation requires ongoing research, collaboration, and
                                                             training to optimize its impact on patient outcomes.
          Furthermore, collaboration between U.S. Military healthcare
          professionals and experts in transfusion medicine can improve   Acknowledgments
          developmental strategies and EFWBT guidelines, with the aim   The authors would like to thank CAPT Sherri Rudinsky, MD
          of ensuring safety, quality control, and compliance with regu-  (Chair – Department of Military and Emergency Medicine
          latory guidelines. EFWBT guidelines should define standard-  at the Uniformed Services University) and Col Cynthia Shen,
          ized protocols to ensure consistent and safe practices, periodic   DO (Operation Gunpowder Course Director – Department of
          proficiency training requirements, and clear administrative   Military and Emergency Medicine at the Uniformed Services
          guidance in WBB protocols. Effective collaboration and a mul-  University) for their unwavering support, expert advice, and
          tifaceted approach toward improving patient outcomes will   mentorship.
          not only save lives but continue to refine and develop transfu-
          sion practices on the battlefield.                 Author Contributions
                                                             ZLB wrote the manuscript; developed the curriculum, train-
          Limitations                                        ing, and evaluation of EFWBT trainees; and developed the
          Limitations in resource acquisition, language barriers between   data for Figure 7. JPC contributed to the Limitations section
          instructors and participants, and participant prior medical train-  and Discussion section of the manuscript; developed the cur-
          ing may have adversely impacted training outcomes. The testing   riculum, training, and evaluation of EFWBT trainees; and de-
          conditions for the EFWBT course involved the use of a simulated   veloped the data for Figure 1. KJM contributed to the Training
          arm/IV trainer, which could degrade the efficacy of training in   Development section; developed the curriculum, training, and
          real-world  applications.  Autologous  blood transfusions and   evaluation of EFWBT trainees; and developed the data for
          assessment of skill proficiency should be incorporated in high-   Appendices A and B. JTS contributed to the Training Partici-
          fidelity simulated TCCC patient scenarios to provide a more   pants section of the manuscript. DWM developed the data for
          accurate assessment of the capabilities of medical providers in   Figures 5 and 6 and contributed to the Results section of the
          treating real-world casualties. Another limitation of our study   manuscript. RC agreed to evaluate all aspects of the work en-
          was the language barrier between instructors and Ukrainian   suring that questions related to the accuracy or integrity of any
          participants. Since the EFWBT program was taught in English,   part of the work were appropriately investigated and resolved.
          which was the Ukrainian participants’ second language, the du-
          ration of didactics and hands-on EFWBT training was expanded   Disclosures
          to allow for adequate translation of certain topics. Presentations,   The authors have nothing to disclose.
          training materials, and assessments translated into the partici-
          pants’ native language may bridge the language barrier between   Funding
          instructors and participants. Furthermore, when comparing the   No funding was received for this work.
          UHPs to third-year medical students, the program may have had
          more of an impact on the UHPs based on the limited exposure   Disclaimer
          to prior experiences in transfusion medicine.      The views expressed are solely those of the authors and do not
                                                             reflect the official policy or position of the Uniformed Services
          Future Research                                    University, the U.S. Army, the U.S. Navy, or the Department
          A longitudinal cohort study of Ukrainian participants should   of Defense.
          be conducted to assess the long-term effects and administrative
          oversight of Ukrainian EFWBT programs and the develop-  References
          ment of concurrent Ukrainian EFWBT programs. Moreover,   1.  Haque U, Naeem A, Wang S, et al. The human toll and humanitar-
          research evaluating enduring Ukrainian EFWBT program   ian crisis of the Russia-Ukraine war: the first 162 days. BMJ Glob
                                                               Health. 2022;7(9):e009550. DOI:10.1136/bmjgh-2022-009550.
          capabilities should be assessed to determine whether UHPs   2.  United Nations High Commissioner for Human Rights. Conflict-
          trained in a Ukrainian-specific EFWBT program are able to re-  related Civilian Casualties in Ukraine. Office of the UN High Com-
          tain long-term confidence and competence in EFWBT. Future   missioner for Human Rights; 2022.  https://ukraine.un.org/sites/

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