Page 37 - JSOM Fall 2023
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TABLE 4  Sternal IO
                    Study             Design       Patients  Success Rate      Providers         Complications
              Harcke et al., 2011 27  Postmortem examination   98  78/98 (79.6%)  —        High placement, at level of
                                series                                                     the clavicle
              Hodgetts et al., 2017 13  Case series  2           —               —         •  Retained sternal needle tips
              Schauer et al., 2019 10  Retrospective descriptive   5  —   •  Medical officer         —
                                review                                    •  Medic
                                                                          •  First-responder
              Vassallo et al., 2014 8  Prospective descriptive   24  19/24 (79.2%)  —      •  Breakage on removal
                                review
              # of studies              4            4           2                1                  3
              IO = intraosseous

              TABLE 5  Humeral IO
              Study                   Design       Patients  Success Rate      Providers         Complications
              Schauer et al., 2019 10  Retrospective descriptive   5  —   •  Medical Officer         —
                                review                                    •  Medic
                                                                          •  First-responder
              Vassallo et al., 2014 8  Prospective descriptive   66  55/66 (83.3%)  —      •  Intra-articular insertion
                                review                                                     •  Breakage on removal
              # of studies              2            2           1                1                  1
              IO = intraosseous

              TABLE 6  Central Lines
              Study                   Design       Patients  Success Rate      Providers         Complications
              DuBose et al., 2017 4  Retrospective descriptive   15  —    Surgical resuscitation     —
                                review                                    team:
                                                                          •  Surgeon
                                                                          •  ER physician
                                                                          •  RN anesthetist
                                                                          •  PA
              Tobin et al., 2015 11  Retrospective descriptive   3  —            —                   —
                                review
              # of studies              2            2           0                1                  0
              ER = emergency room, RN = registered nurse, PA = physician assistant


              FIGURE 1  Prisma Diagram.                          nurses, physician assistants, medics, paramedics, respiratory
                                                                 therapists,  and tactical  combat  casualty  care  providers. The
                                                                 rationale for combat IV access was for TXA administration,
                                             10 duplicates removed
                                                                 analgesia, antibiotics, antiemetics, crystalloid, blood products,
                                                                 and sedation.

                                             1229 studies irrelevant  Tibial Intraosseous
                                                                 Six papers reported on prehospital tibial IO access on a total
                                                                 of 177 patients with 198 attempts. Five of the six papers in-
                                         76 studies excluded
                                                                 cluded the success rate.
                                         31 Vascular access not reported
                                           9 Not a prehospital study
                                          8 Not combat environment  Harcke et al. published a descriptive autopsy case review of
                                          7 Paediatric population
                                                                                                              6
                                          6 Type of vascular access not reported  52 traumatic battlefield deaths who received a tibial IO.  A
                                          5 Wrong patient population
                                           4 Wrong study design  total of 61 tibial IOs were inserted. They utilized post-mortem
                                          2 Duplicate study      CT imaging to identify whether placement was successful. All
                                          2 Not for fluid administration
                                           2 Training environment  right tibial IO insertions were successful (24/24), and 92% of
                                                                 left insertions were successful (34/37). The three unsuccessful
                                                                 insertions describe the needle tip in the soft tissue with the
              including vascular access. The method of access was not spec-  needle not perpendicular to the cortex.
              ified. They reported that two patients (13%) received vascular
              access in the prehospital environment and both were success-  Nadler et al. performed a retrospective review of prehospital
              ful. The level of training of the prehospital provider was not   combat patients who received a tibial IO placed by the Israeli
                                                                                        7
              described.                                         Defense Force Medical Corps.  A total of 36 attempts on 30
                                                                 patients were described. Sixteen of the first attempts at tib-
              Eight papers reported on the type of provider that obtained   ial IO were successful (53%).  A second attempt was made
              prehospital  IV  access.  These  included  physicians,  registered   in five cases with successful access achieved in two. A third

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