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Along with education and resourcing, technological advance-  Disclosure
          ments will also shape the future of WB resuscitation. The Nor-  Products  mentioned  in this  manuscript  were  purchased  by
          wegian THOR program is developing methods of far forward   1SFG(A). The authors have no financial conflicts to disclose.
          blood delivery via unmanned aerial systems, and US developers
          are researching methods to modify blood to make any blood   Author Contributions
          type a universal donor (R. Knight, email communication, 12   TJ created initial blood kits. VM implemented kits through-
          March 2019; S. Patrick, email communication, 11 March   out  1SFG(A) and  presented  to  1SFC(A)  during  innovations
          2019).  Additionally, ruggedizing and miniaturizing of blood   briefing. AS wrote the first draft, and all authors read and
               11
          coolers, or the development of an additive to extend shelf life   approved the final manuscript.
          will likely promote WB practice due to ease of transport.
                                                             References
          Taken together, the next stages of expanded WB use must be:  1.  Cap AP, Beckett A, et al. Joint Trauma System Clinical Prac-
                                                               tice  Guideline: Whole  Blood Transfusion.  May 2018. https://
          1.  Making prehospital WB delivery to casualties on mission   jts.amedd.army.mil/assets/docs/cpgs/JTS_Clinical_Practice
            a standard expectation at the lowest unit levels. The in-  _Guidelines_(CPGs)/Whole_Blood_Transfusion_15_May_2018
                                                               _ID21.pdf
            frastructure to carry and deliver WB at the point of injury   2.  Fisher AD, Miles EA, Cap AP, et al. Tactical  damage control
            exists—medics and providers must now follow through on   resuscitation.  Mil  Med.  2015;180(8):869–875.  doi:10.7205
            executing the practice.                            /MILMED-D-14-00721. PubMed PMID: 26226529.
          2.  As the practice expands, developments in technology and   3.  Strandenes G, Berséus O, Cap AP, et al. Low titer group O whole
            techniques of delivery will further shape and optimize far   blood in emergency situations. Shock. 2014;41(suppl 1):70–75.
            forward blood delivery.                          4.  Warner N, Zheng J, Nix G, et al. Military prehospital use of low
                                                               titer group O whole blood. J Spec Oper Med. 2018;18(1):15–18.
                                                             5.  Clayton D, Perkins J, et al. Fresh frozen plasma. US Army Med
          As SOF strive to establish TTPs and streamline prehospital   Dep J. 2009;January–March:64–67.  www.cs.amedd.army.mil
          WB delivery, we must constantly reassess and refine our pro-  /references_publications.aspx
          cedures, incorporate the latest evidence and technology, and   6.  Spinella PC, Perkins JG, Grathwohl JG, et al. Warm fresh whole
          adapt to an evolving battlefield.                    blood is independently associated with improved survival for pa-
                                                               tients with combat-related traumatic injuries. J Trauma. 2009;66:
                                                               S69–S76.
                                                             7.  Perkins JG, Cap AP, Spinella PC, et al. Comparison of platelet
                                                               transfusion as fresh whole blood versus apheresis platelets for
                                                               massively transfused combat trauma patients (CME). Transfusion.
                                                               2011;51(2):242–252.
                                                             8.  Yazer MH, Cap AP, Spinella PC. Raising the standards on whole
                                                               blood. J Trauma Acute Care Surg. 2017’December 28.
                                                             9.  Fisher AD, Washburn G, et al. Joint Trauma System Clinical Prac-
                                                               tice Guideline: Damage Control Resuscitation in Prolonged Field
                                                               Care. October 2018. https://jts.amedd.army.mil/assets/docs/cpgs
                                                               /Prehospital_En_Route_CPGs/Damage_Control_Resuscitation
                                                               _PFC_01_Oct_2018_ID73.pdf
                                                             10.  Krainin B, Nelson P. MFR: Standard Operating Procedure for
                                                                Special Operations Task Force – Afghanistan (SOTF-A) Special
                                                                Operations  Low  O  Titer  (SOLO)  Blood  Program.  4  December
                                                                2018.
                                                             11.  Norwegian Naval Special Operations Commando (MUK). Blood
                                                                Far Forward: A Research, Education and Training Program to
                                                                Make Whole-Blood Safe and Available on the Battlefield. Octo-
                                                                ber 2012. https://rdcr.org/research/blood-far-forward/






























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