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of  concern. The cardiology community knows that most   10.  Fishbein MC, Siegel RJ. How big are coronary atherosclerotic
          acute events and plaque ruptures occur because of non­  plaques that rupture? Circulation. 1996;94:2662–2666.
          calcified plaque with a lesion of 30% to 70% in luminal
          narrowing. 9,10

          This case is part of a 15­patient pilot project intended   Dr Singh is a practicing cardiologist in Jacksonville, Florida.
          to determine if vulnerable plaques in vulnerable patients   She earned her medical degree at the New York College of
                                                             Osteopathic Medicine and completed her residency in internal
          are predictive of STEMI. Further studies in asymptom­  medicine at Lenox Hill Hospital. She recently completed her
          atic  patients  with  at  least  one  risk  factor  are  needed,   fellowship in cardiology at Northside Hospital in St. Peters­
          using plaque CCTA analysis in combination with serum   burg, Florida.
          biomarker testing to identify vulnerable plaques in vul­
          nerable patients (PROTECT Registry).               Dr Kroman is currently a third­year internal medicine resi­
                                                             dent at Northside Hospital in St. Petersburg and will continue
          We hope that this case study brings light to the impor­  on with her cardiology fellowship at the same location.
          tance of new noninvasive techniques for risk assessment,
          which may lead to solving the problem of predicting   Ms Singh is a third­year medical student at Ross University
          acute coronary events in the future.               School of Medicine. She received a bachelor’s degree in biol­
                                                             ogy from SUNY Stony Brook, State University of New York.
                                                             E­mail: JulieSingh@students.rossu.edu.
          Disclaimer
                                                             Mr Tariq is a third­year medical student at Saba University.
          This study commenced after being approved by the   He received his bachelor’s degree in cellular molecular and mi­
          United States Army Institute of Surgical Research Insti­  crobial biology and his master’s degree in medical science at
          tutional Review Board.                             the University of Calgary in Canada.

                                                             Ms Amin is a second­year medical student at Meharry Medi­
          Disclosures                                        cal College in Nashville, Tennessee. She received bachelor’s
          The authors have nothing to disclose and no conflicts of   degrees in biology and psychology from the University of Flor­
          interest to report.                                ida. E­mail: shetamin@gmail.com.

                                                             Dr Morales-Pablon  is a practicing cardiologist in Tampa,
          References                                         Florida. He earned his medical degree at the University of
                                                             Saint Eustatius School of Medicine and completed his inter­
          1.  Lloyd-Jones D, Adams R, Carnethon M, et al. Heart disease   nal medicine residency at the Medical College of Georgia. He
            and stroke statistics – 2009 update: a report from the American   recently completed an advanced cardiac imaging fellowship at
            Heart  Association Statistics  Committee and  Stroke  Statistics
            Subcommittee. Circulation. 2009;119:480–486.     the University of South Florida and has joined Dr Harrison at
          2.  Hadamitzky M, et al. Optimized prognostic score for coronary   the Harrison Cardiovascular Center.
            computed tomographic angiography: results from the CONFIRM
            Registry. J Am Coll Cardiol. 2013;62:468–476.    Ms Cahill is a practicing physician assistant at Harrison Car­
          3.  Chinnaiyan KM, et al. Coronary computed tomography angiog­  diovascular Center in Tampa, Florida. She received her bach­
            raphy after stress testing. J Am Coll Cardiol. 2012;59:688–695.  elor’s in food science and human nutrition at the University of
          4.  Pontone G, Andreini D. A long­term prognostic value of CT   Florida, and her PA degree at Nova Southeastern University.
            angiography and exercise ECG in patients with suspected
            CAD. J Am Coll Cardiol Imaging. 2013;6:641–650.  Dr Harrison received his medical degree from the University
          5.  Schlett CL, et al. How to assess non­calcified plaque in CT an­  of Kentucky and completed an internship, internal medicine
            giography: delineation methods affect diagnostic accuracy of
            low attenuation plaque by CT for lipid core plaque in histology.   residency, and cardiology fellowship at the University of South
            Eur Heart J. 2013;14:1099–1105.                  Florida, where he was a special fellow of the Florida Heart
          6.  Libby P. Mechanisms of acute coronary syndromes and their   Association. He currently works in office practice in Tampa,
            implications for therapy. N Engl J Med. 2013;368:2004–2013.  Florida, while also serving as a preceptor for the University
          7.  Cross DS, et al. Coronary risk assessment among intermediate   of South Florida Morsani School of Medicine and Saba Uni­
            risk patients using a clinical and biomarker based algorithm de­  versity Medical School of the Netherlands Antilles. He is a
            veloped in validated in two population cohorts. CMRO. 2012;   member of the Special Operations Medical Association and
            28:1819–1830.                                    serves as a civilian consultant for the US Armed Forces as part
          8.  Levine GN, et al. 2011 ACCF/AHA/SCAI guideline for percuta­  of the 6th Medical Group at MacDill Air Force Base in Tampa,
            neous coronary intervention. J Am Coll Cardiol. 2011;58:e44–  Florida.
            e122. doi:10.1016/j.jacc.2011.08.007.
          9.  Giroud D, Li JM, Urban P, et al. Relation of the site of acute
            myocardial infarction to the most severe coronary arterial ste­
            nosis at prior angiography. Am J Cardiol. 1992;69:729–732.





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