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model developed by the USAISR. Dressings with      5.  Mueller GR, Pineda TJ, Xie HX, et al. A novel sponge-
                strong efficacy in the screening studies currently   based wound stasis dressing to treat lethal noncompressible
                being  conducted  by  USAISR  should  undergo  full   hemorrhage. J Trauma Acute Care Surg. 2012;73:S134–
                efficacy and safety studies in both a normal and co-  S139.
                agulopathic animal models.                         6.  Rall JM, Cox JM, Songer AG, et al. Comparison of novel
              4.  Hemostatic dressings should be evaluated for ef-  hemostatic gauzes to QuikClot Combat Gauze in a stan-
                                                                    dardized  swine  model  of  uncontrolled  hemorrhage.  J
                ficacy beyond the 3-hour duration used in current   Trauma Acute Care Surg. 2013;75(2 Suppl 2):S150–S156.
                animal studies out to 12 to 72 hours based in new     7.  Kunio N, Riha GM, Watson KM, et al. Chitosan based
                worldwide operational contingencies in austere en-  hemostatic dressing is associated with decreased blood
                vironments resulting in prolonged pre-hospital care   loss in a swine uncontrolled hemorrhage model.  Am J
                and delayed medical evacuation.                     Surg. 2013;205:505–510.
                                                                   8.  Satterly S, Nelson D, Zwintscher N, et al. Hemostasis in a
              Disclaimers                                           noncompressible hemorrhage model: An end-user evalu-
                                                                    ation of hemostatic agents in a proximal arterial injury. J
              The opinions or assertions contained herein are the pri-  Surg Educ. 2013;70:206–211.
              vate views of the authors and are not to be construed as     9.  Kheirabadi BS, Mace JE, Terrazas IB, et al. Clot inducing
              official or as reflecting the views of the Department of   minerals versus plasma protein dressing for topical treat-
              the Navy, the Department of the Army, or the Depart-  ment of external bleeding in the presence of coagulopa-
              ment of Defense. The recommendation contained herein   thy. J Trauma. 2010;69:1062–1073.
              is the current position of the Department of Defense   10.  Floyd CT, Rothwell SW, Risdahl J, et al. Salmon throm-
              Joint Trauma System CoTCCC. This recommendation       bin-fibrinogen dressing allows greater survival and pre-
                                                                    serves distal blood flow compared to standard kaolin
              is intended to be a guideline only and is not a substitute   gauze in coagulopathic swine with a standardized lethal
              for clinical judgment.                                femoral artery injury. J Spec Oper Med. 2012;12:16–26.
                                                                 11.  King DR. Thirty consecutive uses of a hemostatic bandage
              Disclosures                                           at a US Army Combat Support Hospital and Forward
                                                                    Surgical Team in Operation Iraqi Freedom.  J Trauma.
              The authors have no financial disclosures or anything   2011;71:1775–1778.
              else to disclose.                                  12.  Causey MW, McVay DP, Miller S, et al. The efficacy of
                                                                    Combat Gauze in extreme physiologic conditions. J Surg
              Release                                               Res. 2012;177:301–305.
                                                                 13.  Sena MJ, Douglas G, Gerlach T, et al. A pilot study of
              This document was reviewed by the Director of the     the use of kaolin-impregnated gauze (Combat Gauze) for
              Joint Trauma System, the Public Affairs Office, and the   packing high-grade hepatic injuries in a hypothermic co-
              Operational Security Office of the US Army Institute of   agulopathic swine model. J Surg Res. 2013;183:704–709.
              Surgical Research and approved for unlimited public re-  14.  Kheirabadi BS. Evaluation of topical hemostatic agents
              lease as of 22 April 2014.                            for combat wound treatment.  US Army  Med Dept J.
                                                                    2011;2:25–37.
                                                                 15.  Granville-Chapman J, Jacobs N, Midwinter MJ. Pre-
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              Chitosan-Based Hemostatic Gauze Dressings                                                       55
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