Page 349 - ATP-P 11th Ed

• May cause imbalance.
• May deactivate catecholamine.
• Large solute load may lead to fluid overload.
TMEP use: Crush Injury Protocol

®
Sudafed – See Pseudoephedrine
®
Tadalafil (Cialis )
Class: PDE5 inhibitor
Action: Vasodilator with potential blood pressure-lowering effects
Dose: 10mg
Contraindications: Nitrates – Concomitant use of nitrates in any form. Tadalifil potentiates
the hypotensive effects of nitrates.
Pregnancy Category B
Side-effects:
• Cardiovascular – angina pectoris, chest pain, hypotension, myocardial infarction, pos-
tural hypotension, tachycardia SECTION 3
• Digestive – dry mouth, dysphagia, esophagitis, gastritis
• Ophthalmologic – blurred vision, conjunctivitis (including conjunctival hyperemia), eye pain
Warnings:
• Alpha blockers: coadministration may potentiate the blood pressure lowering effects of
alpha blockers.
• Antihypertensive: coadministration may potentiate the blood pressure lowering effects
of alpha blockers.
• Antacids: simultaneous administration of antacids reduces the absorption of Cialis.
• Ritonavir and HIV protease inhibitors: Increased tadalafil absorption.
• Rifampin: reduced tadalafil absorption 46%. The reduced exposure of tadalafil with the
coadministration of rifampin can be anticipated to decrease the efficacy of tadalafil for
once daily use; the magnitude of decreased efficacy is unknown.
TMEP use: Altitude Illness Protocol
Tenofovir (Viread )
®
GROUNDING medication for personnel on flight status
Indications: Treatment of HIV infection
Dose: 1 pill daily
Contraindications: Known allergy to medication
Pregnancy Category B
Side-effects:
• Immune system disorders
° Allergic reaction
ATP-P Handbook 11th Edition 339