Page 337 - ATP-P 11th Ed

Nifedipine (Procardia )
®
GROUNDING medication for personnel on flight status
Description: An antianginal drug belonging to a class of pharmacological agents, the cal-
cium channel blockers. It works by relaxing blood vessels so blood can flow more easily.
Indications:
• HAPE prophylaxis/treatment.
• Certain types of chest pain (angina). It may help to increase exercise tolerance and
decrease the frequency of angina attacks. Use other medications (e.g., sublingual nitro-
glycerin) to relieve attacks of chest pain.
Contraindications: Known allergy to medication
Pregnancy Category C
Dose: 10mg PO, then 20mg PO q6hr
Side-effects: Primarily vasodilatory in nature (hypotension, peripheral edema)
Warning:
• Although, in most patients, the hypotensive effect of nifedipine is modest and well toler-
ated, occasional patients have had excessive and poorly tolerated hypotension. SECTION 3
TMEP use: Altitude Illness Protocol
Ofirmev – See Acetaminophen

Ondansetron (Zofran )
®
GROUNDING medication for personnel on flight status
Description: Antiemetic
Indications: Prevention of nausea and vomiting
Adult dose:
• Oral dose: 4–8mg PO tid up to 48hr
• IV/IM dose: 4mg IV over 2–5min or 4mg IM tid
Pediatric dose:
• Oral dose:
° Little information available on dosing in children ≤3 years
° 4–11 years of age: 4mg tid up to 48hr
° >12 years of age: 4–8mg PO bid up to 48hr
• IV dose:
° Little information available on dosing in children ≤2 yrs
° 2–12 years old and <40kg: single 0.1mg/kg IV dose over 2–5min
° 2–12 years and >40kg: 4mg IV over 2–5min
K9 Dose: 0.1–0.3mg/kg IV (slow push) q8–12hr OR 0.5–1.0mg/kg PO q12hr
Contraindications: Hypersensitivity to any component of product
Pregnancy Category B
ATP-P Handbook 11th Edition 327