Page 326 - ATP-P 11th Ed
P. 326
Mannitol (Osmotrol )
®
GROUNDING medication for personnel on flight status
Description: Osmotic diuretic
Action: Increases osmolarity of the glomerular filtrate, which increases the reabsorption of
water, increasing sodium and chloride.
Indications:
• Acute Hemolytic Transfusion Reaction (AHTR)
• K9 Head injury
Dose: 1–2g/kg at the rate of 5g/hr
Contraindications:
• Anuria
• Pulmonary edema
• Dehydration
• Congestive heart failure
SECTION 3 • Hypotension
• Hypovolemia
• Hypersensitivity
Pregnancy Category C
Side-effects/precautions:
• Sodium depletion
• Transient volume overload
• Pulmonary edema
• Hypotension (excessive diuresis)
• Angina like chest pain
• Dizziness
• Headache
• Nausea and vomiting
• Chills
• Drug may crystallize at temperatures of 45° F (7.2° C) or lower.
Other notes:
• Use an inline filter.
Mefloquine (Lariam )
®
GROUNDING medication for personnel on flight status
US Army Special Operations Command (USASOC) prohibits the use of mefloquine
for all personnel.
Description: Antimalarial agent
316 SECTION 3 RECOMMENDED DRUG LIST (RDL)

